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2015
- Ross MJ, Bradford SS, Cowan JA.; “Catalytic metallodrugs based on the LaR2C peptide target HCV SLIV IRES RNA,” Dalton Trans. 2015 Dec 28; 44(48):20972-82. doi: 10.1039/c5dt02837j. Epub 2015 Nov 19, PMID: 26583601. Download PDF
- Li J, Pearson SA, Fenk KD, Cowan JA.; “Glutathione-coordinated [2Fe-2S] cluster is stabilized by intramolecular salt bridges,” J Biol Inorg Chem. 2015 Dec; 20(8):1221-7. doi: 10.1007/s00775-015-1301-3. Epub 2015 Oct 14, PMID: 26468125. Download PDF
- Li J, Cowan JA.; “Glutathione-coordinated [2Fe-2S] cluster: a viable physiological substrate for mitochondrial ABCB7 transport,” Chem Commun (Camb). 2015 Feb 11; 51(12):2253-5. doi: 10.1039/c4cc09175b, PMID: 25556595. Download PDF
- Yu Z, Han M, Cowan JA.; “Toward the design of a catalytic metallodrug: selective cleavage of G-quadruplex telomeric DNA by an anticancer copper-acridine-ATCUN complex,” Angew Chem Int Ed Engl. 2015 Feb 2;54(6):1901-5. doi: 10.1002/anie.201410434. Epub 2014 Dec 11, PMID: 25504651. Download PDF
2014
- Fidai I, Hocharoen L, Bradford S, Wachnowsky C, Cowan JA.; “Inactivation of sortase A mediated by metal ATCUN complexes,” J Biol Inorg Chem. 2014 Dec; 19(8):1327-39. doi: 10.1007/s00775-014-1190-x. Epub 2014 Sep 9, PMID: 25217034. Download PDF
- Bradford SS, Ross MJ, Fidai I, Cowan JA.; “Insight into the recognition, binding, and reactivity of catalytic metallodrugs targeting stem loop IIb of hepatitis C IRES RNA,” ChemMedChem. 2014 Jun;9(6):1275-85. doi: 10.1002/cmdc.201400070. Epub 2014 Apr 22, PMID: 24756921. Download PDF
- Amick J, Schlanger SE, Wachnowsky C, Moseng MA, Emerson CC, Dare M, Luo WI, Ithychanda SS, Nix JC, Cowan JA, Page RC, Misra S.; “Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone,” Protein Sci. 2014 Jun; 23(6):833-42. doi: 10.1002/pro.2466. Epub 2014 Apr 17, PMID: 24687350. Download PDF
- Qi W, Li J, Cowan JA.; “A structural model for glutathione-complexed iron-sulfur cluster as a substrate for ABCB7-type transporters,” Chem Commun (Camb). 2014 Apr 14; 50(29):3795-8. doi: 10.1039/c3cc48239a, PMID: 24584132. Download PDF
2013
- Hocharoen L, Joyner JC, Cowan JA.; “N- versus C-domain selectivity of catalytic inactivation of human angiotensin converting enzyme by lisinopril-coupled transition metal chelates,” J Med Chem. 2013 Dec 27; 56(24):9826-36. doi: 10.1021/jm4009345. Epub 2013 Dec 5, PMID: 24228790. Download PDF
- Joyner JC, Cowan JA., “Target-directed catalytic metallodrugs,” Braz J Med Biol Res. 2013 Jun; 46(6):465-85. doi: 10.1590/1414-431X20133086. Epub 2013 Jul 2. Review, PMID: 23828584. Download PDF
- Li J, Ding S, Cowan JA.; “Thermodynamic and structural analysis of human NFU conformational chemistry,” Biochemistry. 2013 Jul 23; 52(29):4904-13. doi: 10.1021/bi400320s. Epub 2013 Jul 15, PMID: 23796308. Download PDF
- Qi W, Li J, Chain CY, Pasquevich GA, Pasquevich AF, Cowan JA.; “Glutathione-complexed iron-sulfur clusters. Reaction intermediates and evidence for a template effect promoting assembly and stability,” Chem Commun (Camb). 2013 Jul 18; 49(56):6313-5. doi: 10.1039/c3cc43620a, PMID: 23739324. Download PDF
- Joyner JC, Keuper KD, Cowan JA.; “Kinetics and Mechanisms of Oxidative Cleavage of HIV RRE RNA by Rev-Coupled Transition Metal Chelates,” Chem Sci. 2013 Apr 1; 4(4):1707-1718, PMID: 23626900. Download PDF
- Joyner JC, Hodnick WF, Cowan AS, Tamuly D, Boyd R, Cowan JA.; “Antimicrobial metallopeptides with broad nuclease and ribonuclease activity,” Chem Commun (Camb). 2013 Mar 14; 49(21):2118-20. doi: 10.1039/c3cc38977d. Epub 2013 Feb 5, PMID: 23380915. Download PDF
- Qi W, Li J, Cowan JA.; “Human ferredoxin-2 displays a unique conformational change,” Dalton Trans. 2013 Mar 7;42(9):3088-91. doi: 10.1039/c2dt32018e. Epub 2012 Dec 3, PMID: 23208207. Download PDF
- Joyner JC, Keuper KD, Cowan JA.; “Analysis of RNA cleavage by MALDI-TOF mass spectrometry,” Nucleic Acids Res. 2013 Jan 7; 41(1):e2. doi: 10.1093/nar/gks811. Epub 2012 Aug 31, PMID: 22941655. Download PDF