{"id":265,"date":"2017-06-01T18:14:52","date_gmt":"2017-06-01T22:14:52","guid":{"rendered":"https:\/\/research.cbc.osu.edu\/gopalan.5\/?page_id=265"},"modified":"2022-08-04T21:09:07","modified_gmt":"2022-08-05T01:09:07","slug":"vg_profile","status":"publish","type":"page","link":"https:\/\/research.cbc.osu.edu\/gopalan.5\/vg_profile\/","title":{"rendered":"Profile"},"content":{"rendered":"

Dr. Venkat Gopalan<\/strong><\/h1>\n
\n

<\/center><\/p>\n

Professor of Chemistry and Biochemistry
\nDepartment of Chemistry and Biochemistry
\nCenter for RNA Biology
\nThe Ohio State University
\n484 West 12th Avenue
\n774 Biological Sciences Building
\nColumbus, OH 43210<\/center><\/p>\n

Phone: (614) 292-1332
\nFax: (614) 292-6773
\nEmail: gopalan.5@osu.edu<\/a><\/center><\/p>\n\n\n\n\n\n\n\n
\n

Education and Training<\/strong><\/h3>\n<\/td>\n<\/tr>\n

1995<\/td>\nVisiting Scientist<\/strong>
\nMRC Laboratory of Molecular Biology, Cambridge, UK
\nMentor: Sir Aaron Klug<\/em><\/td>\n<\/tr>\n
1992 – 1997<\/td>\nPostdoctoral Research Associate<\/strong>
\nYale University, New Haven, CT
\nMentor: Dr. Sidney Altman<\/em><\/td>\n<\/tr>\n
1991<\/td>\nPh.D. in Biochemistry<\/strong>
\nUniversity of New Mexico, Albuquerque,\u00a0NM
\nAdvisor: Dr. Robert H. Glew<\/em><\/td>\n<\/tr>\n
1986<\/td>\nB.S. in Chemistry<\/strong>
\nUniversity of Madras, Madras, India<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n\n
\n

Professional Positions<\/strong><\/h3>\n<\/td>\n<\/tr>\n

2010 to date<\/td>\nProfessor<\/strong>
\nDepartment of Chemistry and Biochemistry (renamed after a merger in July 2012)
\nThe Ohio State University, Columbus, OH<\/td>\n<\/tr>\n
2003 – 2010<\/td>\nAssociate Professor<\/strong>
\nDepartment of Biochemistry
\nThe Ohio State University, Columbus, OH<\/td>\n<\/tr>\n
1998 – 2003<\/td>\nAssistant Professor<\/strong>
\nDepartment of Biochemistry
\nThe Ohio State University, Columbus, OH<\/td>\n<\/tr>\n
1995<\/td>\nVisiting Scientist<\/strong>
\nMRC Laboratory of Molecular Biology, Cambridge, UK
\nMentor: Sir Aaron Klug, Professor and Director<\/em><\/td>\n<\/tr>\n
1992 – 1997<\/td>\nPostdoctoral Research Associate<\/strong>
\nDepartment of Biology
\nYale University, New Haven, CT
\nMentor: Sidney Altman, Sterling Professor of Biology and Chemistry<\/em><\/td>\n<\/tr>\n
1990 – 1991<\/td>\nGraduate Student Researcher<\/strong>
\nDepartment of Biochemistry
\nUniversity of New Mexico, Albuquerque, NM
\nAdvisor: Robert H. Glew, Professor and Chairperson<\/em><\/td>\n<\/tr>\n
1986 – 1990<\/td>\nGraduate Student Researcher<\/strong>
\nDepartment of Microbiology, Biochemistry, and Molecular Biology
\nUniversity of Pittsburgh School of Medicine, Pittsburgh, PA
\nAdvisor: Robert H. Glew, Professor<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

Honors and Awards<\/strong><\/h3>\n<\/td>\n<\/tr>\n

2020<\/td>\nOSU College of Arts and Sciences Student Council Outstanding Teaching Award<\/td>\n<\/tr>\n
2018<\/td>\nOSU College of Arts and Sciences Diversity Enhancement Faculty Award (with Drs. Susan Cole, Department of Molecular Genetics; Jane Jackman, Department of Chemistry and Biochemistry; and Amanda Simcox, Department of Molecular Genetics)<\/td>\n<\/tr>\n
2017 – 2022<\/td>\nMelvin S. Newman Professor of Chemistry and Biochemistry<\/td>\n<\/tr>\n
2010<\/td>\nThe Ohio State University Alumni Distinguished Teaching Award<\/td>\n<\/tr>\n
2010<\/td>\nBringing the World into the Classroom: American Council of Education Award to Recognize Innovative Use of Technology to Promote Internationalization<\/em> (Finalist)<\/td>\n<\/tr>\n
2009<\/td>\nThe Ohio State University Rosalene Sedgwick Faculty Service Award<\/td>\n<\/tr>\n
2008<\/td>\nThe Ohio State University Harlan Hatcher Award for Academic Excellence<\/td>\n<\/tr>\n
2007<\/td>\nThe Ohio State University Department of Biochemistry Award for Excellence<\/td>\n<\/tr>\n
2005<\/td>\nThe Ohio State University College of Biological Sciences Dean’s Award for Classroom Teaching<\/td>\n<\/tr>\n
2004<\/td>\nThe Ohio State University Colleges of Arts and Sciences Student Council Outstanding Teacher Award (Finalist)<\/td>\n<\/tr>\n
2003<\/td>\nThe Ohio State University College of Biological Sciences Dean’s Award for Undergraduate Research Mentoring<\/td>\n<\/tr>\n
2003 – 2008<\/td>\nNational Science Foundation CAREER Award<\/td>\n<\/tr>\n
1995 – 1996<\/td>\nAnna Fuller Cancer Research Fund Postdoctoral Fellowship<\/td>\n<\/tr>\n
1993 – 1995<\/td>\nDonaghue Medical Research Foundation Postdoctoral Fellowship<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

Publications\u00a0<\/strong>(prior to independent position at OSU)<\/em><\/h3>\n<\/td>\n<\/tr>\n

*Corresponding author(s)<\/td>\n<\/td>\n<\/tr>\n
Gopalan V<\/u><\/strong>, Golbik R, Schreiber G, Fersht AR, and Altman S*. (1997) Fluorescence properties of a tryptophan residue in an aromatic core of the protein subunit of ribonuclease P from\u00a0Escherichia coli.<\/em>\u00a0J. Mol. Biol.<\/em>,\u00a0267<\/strong>: 765-769.<\/td>\n<\/td>\n<\/tr>\n
Gopalan V<\/u><\/strong>, Baxevanis AD, Landsman D, and Altman S*. (1997) Analysis of the functional role of conserved residues in the protein subunit of ribonuclease P from\u00a0Escherichia coli<\/em>.\u00a0J. Mol. Biol.<\/em>,\u00a0267<\/strong>: 818-829.<\/td>\n<\/td>\n<\/tr>\n
Gopalan V<\/u><\/strong>, Talbot SJ, and Altman S*. (1994) RNA-protein interactions in RNase P. In K. Nagai and I. Mattaj (Eds.),\u00a0RNA-Protein Interactions \u2013 Frontiers in Molecular Biology<\/em> (pp. 103-126). Oxford, UK: Oxford University Press.<\/td>\n<\/td>\n<\/tr>\n
Glew RH*,\u00a0Gopalan V<\/u><\/strong>, Forsyth GW, and Vander Jagt DJ. (1993) The mammalian cytosolic broad-specificity \u00df<\/em>-glucosidase. In\u00a0A. Esen (Ed.), \u00df<\/em>-glucosidases: Biochemistry and Molecular Biology\u00a0(pp. 83-112). Washington, D.C.: American Chemical Society.<\/td>\n<\/td>\n<\/tr>\n
Gopalan V<\/u><\/strong>, Pastuszyn A, Galey WR Jr, and Glew RH*. (1992) Exolytic hydrolysis of toxic plant glucosides by guinea pig liver cytosolic \u00df<\/em>-glucosidase.\u00a0J. Biol. Chem.<\/em>,\u00a0267<\/strong>: 14027-14032.<\/a><\/td>\n<\/td>\n<\/tr>\n
Gopalan V<\/u><\/strong>, Vander Jagt DJ, Libell DP, and Glew RH*. (1992) Transglucosylation as a probe of the mechanism of action of mammalian cytosolic \u00df<\/em>-glucosidase.\u00a0J. Biol. Chem.<\/em>,\u00a0267<\/strong>: 9629-9638.<\/a><\/td>\n<\/td>\n<\/tr>\n
Lai LB,\u00a0Gopalan V<\/u><\/strong>, and Glew RH*. (1992) Continuous spectrophotometric assays for \u00df<\/em>-glucosidases acting on the plant glucosides L-picein and prunasin.\u00a0Anal. Biochem.<\/em>,\u00a0200<\/strong>: 365-369.<\/td>\n<\/td>\n<\/tr>\n
Glew, RH*,\u00a0Gopalan V<\/u><\/strong>, Hubbell CA, Devraj RV, Lawson RA, Diven WF, and Mannock DA. (1991) 2,3-Di-O<\/em>-tetradecyl-1-O<\/em>-(\u00df<\/em>-D-glucopyranosyl)-sn<\/em>-glycerol is a substrate for human glucocerebrosidase. Biochem. J.<\/em>,\u00a0274<\/strong>: 557-563.<\/a><\/td>\n<\/td>\n<\/tr>\n
Glew RH*,\u00a0Gopalan V<\/u><\/strong>, Hubbell CA, Beutler E, Geil JD, and Lee RE. (1991) A case of nonneurologic Gaucher’s disease that biochemically resembles the neurologic types.\u00a0J. Neuropathol. Exp. Neurol.<\/em>,\u00a050<\/strong>: 108-117.<\/td>\n<\/td>\n<\/tr>\n
Butcher BA,\u00a0Gopalan V<\/u><\/strong>, Lee RE, Richards TC, Waggoner AS, and Glew RH*. (1989) Use of 4-heptylumbelliferyl-\u00df<\/em>-D-glucoside to identify Gaucher’s disease heterozygotes.\u00a0Clin. Chim. Acta<\/em>,\u00a0184<\/strong>: 235-242.<\/td>\n<\/td>\n<\/tr>\n
Gopalan V<\/u><\/strong>, Glew RH*, Libell DP, and DePetro JJ. (1989) The dual effects of alcohols on the kinetic properties of guinea pig liver cytosolic \u00df<\/em>-glucosidase.\u00a0J. Biol. Chem.<\/em>,\u00a0264<\/strong>: 15418-15422.<\/a><\/td>\n<\/td>\n<\/tr>\n
Gopalan V<\/u><\/strong>, Daniels LB, Glew RH*, and Claeyssens M. (1989) Kinetic analysis of the interaction of alkyl glycosides with two human \u00df<\/em>-glucosidases.\u00a0Biochem. J.<\/em>,\u00a0262<\/strong>: 541-548.<\/a><\/td>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Dr. Venkat Gopalan Professor of Chemistry and Biochemistry Department of Chemistry and Biochemistry Center for RNA Biology The Ohio State University 484 West 12th Avenue 774 Biological Sciences Building Columbus, OH 43210 Phone: (614) 292-1332 Fax: (614) 292-6773 Email: gopalan.5@osu.edu Education and Training 1995 Visiting Scientist MRC Laboratory of Molecular Biology, Cambridge, UK Mentor: Sir […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"class_list":["post-265","page","type-page","status-publish","hentry","post-preview"],"jetpack_shortlink":"https:\/\/wp.me\/P8Lmk8-4h","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/pages\/265","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/comments?post=265"}],"version-history":[{"count":89,"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/pages\/265\/revisions"}],"predecessor-version":[{"id":2073,"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/pages\/265\/revisions\/2073"}],"wp:attachment":[{"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/media?parent=265"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}