{"id":784,"date":"2018-04-18T16:37:18","date_gmt":"2018-04-18T20:37:18","guid":{"rendered":"https:\/\/research.cbc.osu.edu\/gopalan.5\/?page_id=784"},"modified":"2023-07-28T16:39:11","modified_gmt":"2023-07-28T20:39:11","slug":"current-members","status":"publish","type":"page","link":"https:\/\/research.cbc.osu.edu\/gopalan.5\/current-members\/","title":{"rendered":"Current Members"},"content":{"rendered":"<h1 style=\"text-align: center;\"><strong>Current Members<\/strong><\/h1>\n<hr>\n\r\n<ul id=\"amoteam-sc-team-975777406\" class=\"amoteam-sc-team amoteam-tiles amoteam-tile-style-2 amoteam-round-style \">\r\n\t<li class=\"amoteam-tiles__item \">\r\n\r\n\t\t<a class=\"amoteam-popup-link\" href=\"javascript:void(0)\" data-mfp-src=\"#amoteam-panel-975777406-792\">\r\n\t\r\n\t\t<div class=\"amoteam-member\">\r\n\t\t\t\t\t\t\t<div class=\"amoteam-member-hover-icon amoteam-member-custom-hover-icon\">\r\n\r\n\t\t\t\t\t\t\t\t\t<img data-recalc-dims=\"1\" height=\"640\" width=\"640\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/04\/OSU_logo.png?resize=640%2C640&#038;ssl=1\">\r\n\t\t\t \t\t\t\t\t<\/div>\r\n\t\t\t\r\n\t\t\t<div class=\"amoteam-member-info amoteam-member-info--al-right \">\r\n\t\t\t\t<div class=\"amoteam-member-name amoteam-member-info__item \">Venkat Gopalan<\/div>\r\n\t\t\t\t\t\t\t\t<div class=\"amoteam-member-subtitle amoteam-member-info__item\">Principal Investigator<\/div>\r\n\t\t\t\t\t\t\t<\/div><!-- .member-info -->\r\n\r\n\t\t\t<div class=\"amoteam-member-img-wrap\">\r\n\t\t\t\t<img decoding=\"async\" class=\"amoteam-member-img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/05\/VG_team2_3.png?resize=360%2C360&ssl=1\" alt=\"Venkat Gopalan\">\r\n\t\t\t<\/div>\r\n\t\t<\/div><!-- .member -->\r\n\r\n\t\t\t<\/a>\r\n\t\t<\/li><!-- .tiles__item -->\r\n\r\n\r\n\t<li class=\"amoteam-tiles__item \">\r\n\r\n\t\t<a class=\"amoteam-popup-link\" href=\"javascript:void(0)\" data-mfp-src=\"#amoteam-panel-975777406-808\">\r\n\t\r\n\t\t<div class=\"amoteam-member\">\r\n\t\t\t\t\t\t\t<div class=\"amoteam-member-hover-icon amoteam-member-custom-hover-icon\">\r\n\r\n\t\t\t\t\t\t\t\t\t<img data-recalc-dims=\"1\" height=\"640\" width=\"640\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/04\/OSU_logo.png?resize=640%2C640&#038;ssl=1\">\r\n\t\t\t \t\t\t\t\t<\/div>\r\n\t\t\t\r\n\t\t\t<div class=\"amoteam-member-info amoteam-member-info--al-right \">\r\n\t\t\t\t<div class=\"amoteam-member-name amoteam-member-info__item \">Lien B. Lai<\/div>\r\n\t\t\t\t\t\t\t\t<div class=\"amoteam-member-subtitle amoteam-member-info__item\">Senior Research Scientist<\/div>\r\n\t\t\t\t\t\t\t<\/div><!-- .member-info -->\r\n\r\n\t\t\t<div class=\"amoteam-member-img-wrap\">\r\n\t\t\t\t<img decoding=\"async\" class=\"amoteam-member-img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/05\/LL_team2_2.png?resize=360%2C360&ssl=1\" alt=\"Lien B. Lai\">\r\n\t\t\t<\/div>\r\n\t\t<\/div><!-- .member -->\r\n\r\n\t\t\t<\/a>\r\n\t\t<\/li><!-- .tiles__item -->\r\n\r\n\r\n\t<li class=\"amoteam-tiles__item \">\r\n\r\n\t\t<a class=\"amoteam-popup-link\" href=\"javascript:void(0)\" data-mfp-src=\"#amoteam-panel-975777406-1004\">\r\n\t\r\n\t\t<div class=\"amoteam-member\">\r\n\t\t\t\t\t\t\t<div class=\"amoteam-member-hover-icon amoteam-member-custom-hover-icon\">\r\n\r\n\t\t\t\t\t\t\t\t\t<img data-recalc-dims=\"1\" height=\"640\" width=\"640\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/04\/OSU_logo.png?resize=640%2C640&#038;ssl=1\">\r\n\t\t\t \t\t\t\t\t<\/div>\r\n\t\t\t\r\n\t\t\t<div class=\"amoteam-member-info amoteam-member-info--al-right \">\r\n\t\t\t\t<div class=\"amoteam-member-name amoteam-member-info__item \">Walter J. Zahurancik<\/div>\r\n\t\t\t\t\t\t\t\t<div class=\"amoteam-member-subtitle amoteam-member-info__item\">Reseach Senior Associate<\/div>\r\n\t\t\t\t\t\t\t<\/div><!-- .member-info -->\r\n\r\n\t\t\t<div class=\"amoteam-member-img-wrap\">\r\n\t\t\t\t<img decoding=\"async\" class=\"amoteam-member-img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/08\/WZ_team2_2.png?resize=360%2C360&ssl=1\" alt=\"Walter J. Zahurancik\">\r\n\t\t\t<\/div>\r\n\t\t<\/div><!-- .member -->\r\n\r\n\t\t\t<\/a>\r\n\t\t<\/li><!-- .tiles__item -->\r\n\r\n\r\n\t<li class=\"amoteam-tiles__item  amoteam-js-round-fix\">\r\n\r\n\t\t<a class=\"amoteam-popup-link\" href=\"javascript:void(0)\" data-mfp-src=\"#amoteam-panel-975777406-1573\">\r\n\t\r\n\t\t<div class=\"amoteam-member\">\r\n\t\t\t\t\t\t\t<div class=\"amoteam-member-hover-icon amoteam-member-custom-hover-icon\">\r\n\r\n\t\t\t\t\t\t\t\t\t<img data-recalc-dims=\"1\" height=\"640\" width=\"640\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/04\/OSU_logo.png?resize=640%2C640&#038;ssl=1\">\r\n\t\t\t \t\t\t\t\t<\/div>\r\n\t\t\t\r\n\t\t\t<div class=\"amoteam-member-info amoteam-member-info--al-right \">\r\n\t\t\t\t<div class=\"amoteam-member-name amoteam-member-info__item \">Moulisubhro Datta<\/div>\r\n\t\t\t\t\t\t\t\t<div class=\"amoteam-member-subtitle amoteam-member-info__item\">Graduate Student<\/div>\r\n\t\t\t\t\t\t\t<\/div><!-- .member-info -->\r\n\r\n\t\t\t<div class=\"amoteam-member-img-wrap\">\r\n\t\t\t\t<img decoding=\"async\" class=\"amoteam-member-img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2019\/05\/datta.79-e1672849267694.jpg?resize=300%2C321&ssl=1\" alt=\"Moulisubhro Datta\">\r\n\t\t\t<\/div>\r\n\t\t<\/div><!-- .member -->\r\n\r\n\t\t\t<\/a>\r\n\t\t<\/li><!-- .tiles__item -->\r\n\r\n\r\n\t<li class=\"amoteam-tiles__item \">\r\n\r\n\t\t<a class=\"amoteam-popup-link\" href=\"javascript:void(0)\" data-mfp-src=\"#amoteam-panel-975777406-2084\">\r\n\t\r\n\t\t<div class=\"amoteam-member\">\r\n\t\t\t\t\t\t\t<div class=\"amoteam-member-hover-icon amoteam-member-custom-hover-icon\">\r\n\r\n\t\t\t\t\t\t\t\t\t<img data-recalc-dims=\"1\" height=\"640\" width=\"640\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/04\/OSU_logo.png?resize=640%2C640&#038;ssl=1\">\r\n\t\t\t \t\t\t\t\t<\/div>\r\n\t\t\t\r\n\t\t\t<div class=\"amoteam-member-info amoteam-member-info--al-right \">\r\n\t\t\t\t<div class=\"amoteam-member-name amoteam-member-info__item \">Rachel Hemmerlin<\/div>\r\n\t\t\t\t\t\t\t\t<div class=\"amoteam-member-subtitle amoteam-member-info__item\">Graduate Student<\/div>\r\n\t\t\t\t\t\t\t<\/div><!-- .member-info -->\r\n\r\n\t\t\t<div class=\"amoteam-member-img-wrap\">\r\n\t\t\t\t<img decoding=\"async\" class=\"amoteam-member-img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2023\/01\/Rachel-scaled-e1677520154707.jpg?resize=640%2C640&ssl=1\" alt=\"Rachel Hemmerlin\">\r\n\t\t\t<\/div>\r\n\t\t<\/div><!-- .member -->\r\n\r\n\t\t\t<\/a>\r\n\t\t<\/li><!-- .tiles__item -->\r\n\r\n\r\n\t<li class=\"amoteam-tiles__item  amoteam-js-round-fix\">\r\n\r\n\t\t<a class=\"amoteam-popup-link\" href=\"javascript:void(0)\" data-mfp-src=\"#amoteam-panel-975777406-2348\">\r\n\t\r\n\t\t<div class=\"amoteam-member\">\r\n\t\t\t\t\t\t\t<div class=\"amoteam-member-hover-icon amoteam-member-custom-hover-icon\">\r\n\r\n\t\t\t\t\t\t\t\t\t<img data-recalc-dims=\"1\" height=\"640\" width=\"640\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/04\/OSU_logo.png?resize=640%2C640&#038;ssl=1\">\r\n\t\t\t \t\t\t\t\t<\/div>\r\n\t\t\t\r\n\t\t\t<div class=\"amoteam-member-info amoteam-member-info--al-right \">\r\n\t\t\t\t<div class=\"amoteam-member-name amoteam-member-info__item \">Kumar Vaibhav<\/div>\r\n\t\t\t\t\t\t\t\t<div class=\"amoteam-member-subtitle amoteam-member-info__item\">Graduate Student<\/div>\r\n\t\t\t\t\t\t\t<\/div><!-- .member-info -->\r\n\r\n\t\t\t<div class=\"amoteam-member-img-wrap\">\r\n\t\t\t\t<img decoding=\"async\" class=\"amoteam-member-img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2025\/08\/Screenshot-2025-08-12-155436-e1768927168408.png?resize=340%2C370&ssl=1\" alt=\"Kumar Vaibhav\">\r\n\t\t\t<\/div>\r\n\t\t<\/div><!-- .member -->\r\n\r\n\t\t\t<\/a>\r\n\t\t<\/li><!-- .tiles__item -->\r\n\r\n<\/ul><!-- .sc-team -->\r\n<script>amoTeamVars.teamSC.push({\"type\":\"team\",\"scID\":\"#amoteam-sc-team-975777406\",\"itemWidth\":250,\"itemMargin\":20,\"align\":\"center\",\"fullWidth\":\"yes\",\"panel\":\"right\"})<\/script><div class=\"amoteam-panels\">\r\n<div id=\"amoteam-panel-975777406-792\" class=\"amoteam-panel mfp-hide amoteam-panel-align-right amoteam-panel-pf-image \"\r\n     data-align=\"right\" data-format=\"image\">\r\n\r\n\t<div class=\"amoteam-panel__header\">\r\n\r\n\t\t\r\n\r\n\t\t<button type=\"button\" class=\"amoteam-btn amoteam-btn-rc-square amoteam-btn-panel-close\" data-dismiss=\"modal\" aria-label=\"Close Panel\"><i aria-hidden=\"true\" class=\"amoteam-icon-close\"><\/i><\/button>\r\n\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__img-wrap\">\r\n\t\t\t\t\t\t\t<img data-recalc-dims=\"1\" height=\"640\" width=\"640\" decoding=\"async\" class=\"amoteam-panel__img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/05\/VG_team2_profile.png?resize=640%2C640&#038;ssl=1\" data-img-preloaded=\"1\" alt=\"Venkat Gopalan\">\r\n\t\t\t\t\t<\/div><!-- .panel__img-wrap -->\r\n\r\n\t\t\r\n\t\t<div class=\"amoteam-panel__heading\">\r\n\t\t\t<h3 class=\"amoteam-panel__title amoteam-panel__heading-item\">Venkat Gopalan<\/h3>\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__subtitle amoteam-panel__heading-item\">Principal Investigator<\/div>\r\n\t\t\t\t\t<\/div>\r\n\r\n\t<\/div><!-- .panel__header -->\r\n\r\n\t<div class=\"amoteam-panel__content\">\r\n\t\t\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Email<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;<a href=\"mailto:gopalan.5@osu.edu\">gopalan.5@osu.edu<\/a><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Education and Training<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr>\n<p><strong>Visiting Scientist \u2013 Medical Research Council (MRC) Laboratory of Molecular Biology (Cambridge, UK)<\/strong><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;Advisor: Sir Aaron Klug<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Conducted crystallographic studies of bacterial RNase P<\/p>\n<hr>\n<p><strong>Postdoctoral Research Associate \u2013 Yale University (New Haven, CT)<\/strong><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;Advisor: Dr. Sidney Altman<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Mapped RNA-protein interactions in <em>Escherichia coli<\/em> RNase P<\/p>\n<hr>\n<p><strong>Ph.D. \u2013 University of New Mexico (Albuquerque, NM)<\/strong><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;Program: Biochemistry<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Advisor: Dr. Robert H. Glew<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Dissertation: Mechanism of action of mammalian cytosolic <em>\u00df<\/em>-glucosidase: implications for biotransformation of toxic plant glucosides<\/p>\n<hr>\n<p><strong>B.S. \u2013 University of Madras (Madras, India)<\/strong><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;Major: Chemistry<\/p>\n<hr>\n<p><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Publications<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;Publications since starting his own independent research group at OSU are listed <a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/publications\/\">here<\/a>.<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Publications from his time as a graduate student and postdoctoral researcher are listed <a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/vg_profile\/\">here<\/a>.<\/p>\n\t<\/div><!-- .panel__content -->\r\n\r\n<\/div><!-- .panel -->\r\n<div id=\"amoteam-panel-975777406-808\" class=\"amoteam-panel mfp-hide amoteam-panel-align-right amoteam-panel-pf-image \"\r\n     data-align=\"right\" data-format=\"image\">\r\n\r\n\t<div class=\"amoteam-panel__header\">\r\n\r\n\t\t\r\n\r\n\t\t<button type=\"button\" class=\"amoteam-btn amoteam-btn-rc-square amoteam-btn-panel-close\" data-dismiss=\"modal\" aria-label=\"Close Panel\"><i aria-hidden=\"true\" class=\"amoteam-icon-close\"><\/i><\/button>\r\n\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__img-wrap\">\r\n\t\t\t\t\t\t\t<img data-recalc-dims=\"1\" height=\"640\" width=\"640\" decoding=\"async\" class=\"amoteam-panel__img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/05\/LL_team2_profile.png?resize=640%2C640&#038;ssl=1\" data-img-preloaded=\"1\" alt=\"Lien B. Lai\">\r\n\t\t\t\t\t<\/div><!-- .panel__img-wrap -->\r\n\r\n\t\t\r\n\t\t<div class=\"amoteam-panel__heading\">\r\n\t\t\t<h3 class=\"amoteam-panel__title amoteam-panel__heading-item\">Lien B. Lai<\/h3>\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__subtitle amoteam-panel__heading-item\">Senior Research Scientist<\/div>\r\n\t\t\t\t\t<\/div>\r\n\r\n\t<\/div><!-- .panel__header -->\r\n\r\n\t<div class=\"amoteam-panel__content\">\r\n\t\t\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Email<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;<a href=\"mailto:lai.104@osu.edu\">lai.104@osu.edu<\/a><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Current Projects<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;Supervisor: Dr. Mark P. Foster<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Determine how a mutation in a central nervous system (CNS)-specific tRNA-Arg, which has been linked to neurodegeneration in mice, impacts tRNA biogenesis [collaboration with Dr. Susan L. Ackerman (UCSD)]<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Utilize sequence analyses, hydroxyl radical-mediated footprinting experiments, and native mass spectrometry to identify novel structural elements in halophilic archaeal RNase P RNAs [collaboration with Drs. Charles J. Daniels and Vicki H. Wysocki (OSU)]<br \/>\n<\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Education and Training<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr>\n<p><strong>Postdoctoral Researcher \u2013 The Ohio State University (Columbus, OH)<\/strong><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;Department: Biochemistry<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Advisor: Dr. Venkat Gopalan<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Purified and characterized plant RNase P<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Assessed the efficacy of external guide sequences (EGS) and M1GS for targeted RNA degradation in plants<\/p>\n<hr>\n<p><strong>Postdoctoral Researcher \u2013 The Ohio State University (Columbus, OH)<\/strong><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;Department: Plant Biology<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Advisor: Dr. Fred D. Sack<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Identified and characterized the <em>Arabidopsis thaliana<\/em> FOUR LIPS gene that restricts the number of divisions by the guard mother cell to one, thereby preventing the appearance of &#8220;four lips&#8221;, which arise from two (or more) cell divisions<\/p>\n<hr>\n<p><strong>Ph.D. \u2013 Yale University (New Haven, CT)<\/strong><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;Program: Molecular, Cellular, and Developmental Biology (MCDB)<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Advisor: Dr. Timothy M. Nelson<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Dissertation: Regulation of cell-specific expression of C4 photosynthetic genes in <em>Flaveria<\/em>: a comparative study<\/p>\n<hr>\n<p><strong>B.S. \u2013 University of New Mexico (Albuquerque, NM)<\/strong><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;Major: Biochemistry<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Advisor: Dr. Robert H. Glew<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Thesis: Continuous spectrophotometric assays for <em>\u00df<\/em>-glucosidases acting on the plant glucosides L-picein and prunasin<\/p>\n<hr>\n<p><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Publications<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr>\n<p>\u2022&nbsp;&nbsp;&nbsp;<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Daniels_RNA_2019.pdf\">Daniels CJ*, Lai LB, Chen T-H, and Gopalan V. (2019) Both kinds of RNase P in all domains of life: Surprises galore. <em>RNA<\/em>, <strong>25<\/strong>: 286-291.<\/a><br \/>\n\u2022&nbsp;&nbsp;&nbsp;<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Lai_NAR_2017.pdf\">Lai LB*, Tanimoto A^, Lai SM^, Chen W-Y, Marathe IA, Westhof E, Wysocki VH, and Gopalan V*. (2017) A novel double kink-turn module in euryarchaeal RNase P RNAs. <em>Nucleic Acids Res.<\/em>, <strong>45<\/strong>: 7432-7440.<\/a> [<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Lai_NAR_2017_SI.pdf\">SI<\/a>] <strong><em>^joint second authors<\/em><\/strong><br \/>\n\u2022&nbsp;&nbsp;&nbsp;Lei Q, Lee E, Keerthisinghe S, Lai L, Li M, Lucas JR, Wen X, Ren X*, and Sack FD. (2015) The <em>FOUR LIPS<\/em> and <em>MYB88<\/em> transcription factor genes are widely expressed in <em>Arabidopsis thaliana<\/em> during development. <em>Am. J. Bot.<\/em>, <strong>102<\/strong>: 1521-1528.<br \/>\n\u2022&nbsp;&nbsp;&nbsp;<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Manivannan_PLoSGenet_2015.pdf\">Manivannan SN, Lai LB, Gopalan V*, and Simcox A*. (2015) Transcriptional control of an essential ribozyme in <em>Drosophila<\/em> reveals an ancient evolutionary divide in animals. <em>PLoS Genet.<\/em>, <strong>11<\/strong>: e1004893.<\/a> [SI <a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Manivannan_PLoSGenet_2015_SIpt1.zip\">1<\/a>, <a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Manivannan_PLoSGenet_2015_SIpt2.zip\">2<\/a>]<br \/>\n\u2022&nbsp;&nbsp;&nbsp;<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Lai_NAR_2014.pdf\">Lai SM, Lai LB, Foster MP*, and Gopalan V*. (2014) The L7Ae protein binds to two kink-turns in the <em>Pyrococcus furiosus<\/em> RNase P RNA. <em>Nucleic Acids Res.<\/em>, <strong>42<\/strong>: 13328-13338.<\/a> [<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Lai_NAR_2014_SI.zip\">SI<\/a>]<br \/>\n\u2022&nbsp;&nbsp;&nbsp;<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Ma_AngewChemIntEdEngl_2014.pdf\">Ma X\u00b0, Lai LB\u00b0, Lai SM\u00b0, Tanimoto A, Foster MP, Wysocki VH*, and Gopalan V*. (2014) Uncovering the stoichiometry of <em>Pyrococcus furiosus<\/em> RNase P, a multi-subunit catalytic ribonucleoprotein complex, by surface-induced dissociation and ion mobility mass spectrometry. <em>Angew. Chem. Int. Ed. Engl.<\/em>, <strong>53<\/strong>: 11483-11487.<\/a> [<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Ma_AngewChemIntEdEngl_2014_SI.pdf\">SI<\/a>] <strong><em>\u00b0joint first authors<\/em><\/strong><br \/>\n\u2022&nbsp;&nbsp;&nbsp;<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/Biofuels\/GovindaRajulu_MycolProgress_2014.pdf\">Govinda Rajulu MB\u00b0, Lai LB\u00b0, Murali TS, Gopalan V*, and Suryanarayanan TS*. (2014) Several fungi from fire-prone forests of southern India can utilize furaldehydes. <em>Mycol. Prog.<\/em>, <strong>13<\/strong>: 1049-1056.<\/a> <strong><em>\u00b0joint first authors<\/em><\/strong><br \/>\n\u2022&nbsp;&nbsp;&nbsp;<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/Biofuels\/Han_ApplEnvironMicrobiol_2013.pdf\">Han B\u00b0, Ujor V\u00b0, Lai LB, Gopalan V, and Ezeji TC*. (2013) Use of proteomic analysis to elucidate the role of calcium in acetone-butanol-ethanol fermentation by <em>Clostridium beijerinckii<\/em> NCIMB 8052. <em>Appl. Environ. Microbiol.<\/em>, <strong>79<\/strong>: 282-293.<\/a> [<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/Biofuels\/Han_ApplEnvironMicrobiol_2013_SI.pdf\">SI<\/a>] <strong><em>\u00b0joint first authors<\/em><\/strong><br \/>\n\u2022&nbsp;&nbsp;&nbsp;<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Chen_NAR_2012.pdf\">Chen W-Y, Singh D, Lai LB, Stiffler MA, Lai HD, Foster MP, and Gopalan V*. (2012) Fidelity of tRNA 5\u2032-maturation: a possible basis for the functional dependence of archaeal and eukaryal RNase P on multiple protein cofactors. <em>Nucleic Acids Res.<\/em>, <strong>40<\/strong>: 4666-4680.<\/a> [<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Chen_NAR_2012_SI.zip\">SI<\/a>]<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Lai LB, Bernal-Bayard P, Mohannath G, Lai SM, Gopalan V*, and Vioque A*. (2011) A functional RNase P protein subunit of bacterial origin in some eukaryotes. <em>Mol. Genet. Genomics<\/em>, <strong>286<\/strong>: 359-369.<br \/>\n\u2022&nbsp;&nbsp;&nbsp;<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Lai_PNAS_2010.pdf\">Lai LB\u00b0, Chan PP\u00b0, Cozen AE, Bernick DL, Brown JW, Gopalan V*, and Lowe TM*. (2010) Discovery of a minimal form of RNase P in <em>Pyrobaculum<\/em>. <em>Proc. Natl. Acad. Sci. USA<\/em>, <strong>107<\/strong>: 22493-22498.<\/a> [<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Lai_PNAS_2010_SI.pdf\">SI<\/a>] <strong><em>(Highlighted on the cover and in a commentary)<\/em><\/strong> <strong><em>\u00b0joint first authors<\/em><\/strong><br \/>\n\u2022&nbsp;&nbsp;&nbsp;<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Cho_PNAS_2010.pdf\">Cho I-M, Lai LB, Susanti D, Mukhopadhyay B, and Gopalan V*. (2010) Ribosomal protein L7Ae is a subunit of archaeal RNase P. <em>Proc. Natl. Acad. Sci. USA<\/em>, <strong>107<\/strong>: 14573-14578.<\/a> [<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Cho_PNAS_2010_SI.pdf\">SI<\/a>]<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Lai LB, Cho I-M, Chen W-Y, and Gopalan V*. (2010) Archaeal RNase P: a mosaic of its bacterial and eukaryal relatives. In F Liu and S Altman (Eds.), <em>Ribonuclease P<\/em> (Protein Reviews, vol. 10; pp. 153-172). New York, NY: Springer Science + Business Media, LLC.<br \/>\n\u2022&nbsp;&nbsp;&nbsp;McClain WH*, Lai LB, and Gopalan V. (2010) Trials, travails, and triumphs: an account of RNA catalysis in RNase P. <em>J. Mol. Biol.<\/em>, <strong>397<\/strong>: 627-646.<br \/>\n\u2022&nbsp;&nbsp;&nbsp;<a href=\"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/Publications\/RNaseP\/Lai_FEBSLetters_2010.pdf\">Lai LB, Vioque A, Kirsebom LA*, and Gopalan V*. (2010) Unexpected diversity of RNase P, an ancient tRNA processing enzyme: challenges and prospects. <em>FEBS Lett.<\/em>, <strong>584<\/strong>: 287-296.<\/a> <strong><em>(Invited article for a special issue)<\/em><\/strong><br \/>\n\u2022&nbsp;&nbsp;&nbsp;Gopichandran V, Lai LB, and Gopalan V*. (2006) Protein-energy malnutrition. In RH Glew and MD Rosenthal (Eds.), <em>Clinical Studies in Medical Biochemistry<\/em>, (3rd edition; pp. 255-265). New York, NY: Oxford University Press.<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Lai LB, Gopichandran V, and Gopalan V*. (2006) Tangier disease: a disorder in the reverse cholesterol transport pathway. In RH Glew and MD Rosenthal (Eds.), <em>Clinical Studies in Medical Biochemistry<\/em>, (3rd edition; pp. 159-166). New York, NY: Oxford University Press.<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Lai LB, Nadeau JA, Lucas J, Lee E-K, Nakagawa T, Zhao L, Geisler M, and Sack FD*. (2005) The <em>Arabidopsis<\/em> R2R3 MYB proteins FOUR LIPS and MYB88 restrict divisions late in the stomatal cell lineage. <em>Plant Cell<\/em>, <strong>17<\/strong>: 2754-2767.<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Pulukkunat DK, Stephen Raj ML, Pattanayak D, Lai LB, and Gopalan V*. (2003) Exploring the potential of plant RNase P as a functional genomics tool. In E. Grotewold (Ed.), <em>Plant Functional Genomics<\/em> (Methods in Molecular Biology, vol. 236; pp. 295-309). Totowa, NJ: Humana Press, Inc.<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Tsai H-Y\u00b0, Lai LB\u00b0, and Gopalan V*. (2002) A modified pBluescript-based vector for facile cloning and transcription of RNAs. <em>Anal. Biochem.<\/em>, <strong>303<\/strong>: 214-217. <strong><em>\u00b0joint first authors<\/em><\/strong><br \/>\n\u2022&nbsp;&nbsp;&nbsp;Lai LB, Tausta SL, and Nelson TM*. (2002) Differential regulation of transcripts encoding cytosolic NADP-malic enzyme in C<sub>3<\/sub> and C<sub>4<\/sub> <em>Flaveria<\/em> species. <em>Plant Physiol.<\/em>, <strong>128<\/strong>: 140-149.<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Lai LB, Wang L, and Nelson TM*. (2002) Distinct but conserved functions for two chloroplastic NADP-malic enzyme isoforms in C<sub>3<\/sub> and C<sub>4<\/sub> <em>Flaveria<\/em> species. <em>Plant Physiol.<\/em>, <strong>128<\/strong>: 125-139.<br \/>\n\u2022&nbsp;&nbsp;&nbsp;McGonigle B, Lai LB, and Nelson T. (1996) Sequences of seven cDNAs (Accession Nos. U29933 to U29939) encoding the rubisco small subunit from <em>Flaveria pringlei<\/em>. <em>Plant Physiol.<\/em>, <strong>111<\/strong>: 1354 (Plant Gene Register PGR96-057).<br \/>\n\u2022&nbsp;&nbsp;&nbsp;Lai LB, Gopalan V, and Glew RH*. (1992) Continuous spectrophotometric assays for <em>\u00df<\/em>-glucosidases acting on the plant glucosides L-picein and prunasin. <em>Anal. Biochem.<\/em>, <strong>200<\/strong>: 365-369.<br \/>\n<\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\t<\/div><!-- .panel__content -->\r\n\r\n<\/div><!-- .panel -->\r\n<div id=\"amoteam-panel-975777406-1004\" class=\"amoteam-panel mfp-hide amoteam-panel-align-right amoteam-panel-pf-image \"\r\n     data-align=\"right\" data-format=\"image\">\r\n\r\n\t<div class=\"amoteam-panel__header\">\r\n\r\n\t\t\r\n\r\n\t\t<button type=\"button\" class=\"amoteam-btn amoteam-btn-rc-square amoteam-btn-panel-close\" data-dismiss=\"modal\" aria-label=\"Close Panel\"><i aria-hidden=\"true\" class=\"amoteam-icon-close\"><\/i><\/button>\r\n\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__img-wrap\">\r\n\t\t\t\t\t\t\t<img data-recalc-dims=\"1\" height=\"640\" width=\"640\" decoding=\"async\" class=\"amoteam-panel__img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2018\/08\/WZ_team2_profile.png?resize=640%2C640&#038;ssl=1\" data-img-preloaded=\"1\" alt=\"Walter J. Zahurancik\">\r\n\t\t\t\t\t<\/div><!-- .panel__img-wrap -->\r\n\r\n\t\t\r\n\t\t<div class=\"amoteam-panel__heading\">\r\n\t\t\t<h3 class=\"amoteam-panel__title amoteam-panel__heading-item\">Walter J. Zahurancik<\/h3>\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__subtitle amoteam-panel__heading-item\">Reseach Senior Associate<\/div>\r\n\t\t\t\t\t<\/div>\r\n\r\n\t<\/div><!-- .panel__header -->\r\n\r\n\t<div class=\"amoteam-panel__content\">\r\n\t\t\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Email<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a0<a href=\"mailto:zahurancik.2@osu.edu\">zahurancik.2@osu.edu<\/a><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Current Projects<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a0Investigate the functional contributions of protein subunits to substrate recognition by archaeal RNase P RNA using single-molecule fluorescence-based techniques [collaboration with Dr. Michael G. Poirier (OSU)]<br \/>\n<\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Education and Training<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p><strong>Postdoctoral Researcher \u2013 The Ohio State University (Columbus, OH)<\/strong><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a02019-2020 OSU Center for RNA Biology (CRB) Researcher<br \/>\n\u2022\u00a0\u00a0\u00a02020-2022 Pelotonia Postdoctoral Research Fellow<\/p>\n<hr \/>\n<p><strong>Ph.D. \u2013 The Ohio State University (Columbus, OH)<\/strong><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a0Program: Ohio State Biochemistry Program<br \/>\n\u2022\u00a0\u00a0\u00a0Advisor: Dr. Zucai Suo<br \/>\n\u2022\u00a0\u00a0\u00a0Dissertation: Kinetic characterization of human DNA polymerase \u0395<\/p>\n<hr \/>\n<p><strong>B.S. \u2013 The Ohio State University (Columbus, OH)<\/strong><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a0Major: Biochemistry<br \/>\n\u2022\u00a0\u00a0\u00a0Advisor: Dr. Zucai Suo<br \/>\n\u2022\u00a0\u00a0\u00a0Thesis: Characterization of replicative and error-prone DNA polymerases<\/p>\n<hr \/>\n<p><strong>Undergraduate Research Assistant \u2013 The Ohio State University (Columbus, OH)<\/strong><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a0Department: Biochemistry<br \/>\n\u2022\u00a0\u00a0\u00a0Advisor: Dr. Zhengrong Wu<br \/>\n\u2022\u00a0\u00a0\u00a0Cloned, overexpressed, and purified mutants of a nucleotide hydrolase (RCL) for biochemical studies aimed at defining its mechanism of action<\/p>\n<hr \/>\n<p><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Publications<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a0Kimsey IJ\u00b0, Szymanski ES\u00b0, Zahurancik WJ, Shakya A, Xue Y, Chu CC, Sathyamoorthy B, Suo Z*, and Al-Hashimi HM*. (2018) Dynamic basis for dG\u2022dT misincorporation via tautomerization and ionization. <em>Nature<\/em>, <strong>554<\/strong>: 195-201. <strong><em>\u00b0joint first authors<\/em><\/strong><br \/>\n\u2022\u00a0\u00a0\u00a0Campbell BB\u00b0, Light N\u00b0, Fabrizio D, Zatzman M, Fuligni F, de Borja R, Davidson S, Edwards M, Elvin JA, Hodel KP, Zahurancik WJ, Suo Z, Lipman T, Wimmer K, Kratz CP, Bowers DC, Laetsch TW, Dunn GP, Johanns TM, Grimmer MR, Smirnov IV, Larouche V, Samuel D, Bronsema A, Osborn M, Stearns D, Raman P, Cole KA, Storm PB, Yalon M, Opocher E, Mason G, Thomas GA, Sabel M, George B, Ziegler DS, Lindhort S, Issai VM, Constantini S, Toledano H, Elhasid R, Farah R, Dvir R, Dirks P, Huang A, Galati MA, Chung J, Ramaswamy V, Irwin MS, Aronson M, Durno C, Taylor MD, Rechavi G, Maris JM, Bouffet E, Hawkins C, Costello JF, Meyn MS, Pursell ZF, Malkin D, Tabori U*, and Shlien A*. (2017) Comprehensive analysis of hypermutation in human cancer. <em>Cell<\/em>, <strong>171<\/strong>: 1042-1056.e10. <strong><em>\u00b0joint first authors<\/em><\/strong><br \/>\n\u2022\u00a0\u00a0\u00a0Wu J, Wang P, Li L, Williams NL, Ji D, Zahurancik WJ, You C, Wang J, Suo Z, and Wang Y. (2017) Replication studies of carboxymethylated DNA lesions in human cells. <em>Nucleic Acids Res.<\/em>, <strong>45<\/strong>: 7276-7284.<br \/>\n\u2022\u00a0\u00a0\u00a0Vyas R, Reed AJ, Raper AT, Zahurancik WJ, Wallenmeyer PC, and Suo Z*. (2017) Structural basis for the D-stereoselectivity of human DNA polymerase \u00df. <em>Nucleic Acids Res.<\/em>, <strong>45<\/strong>: 6228-6237.<br \/>\n\u2022\u00a0\u00a0\u00a0Tokarsky EJ, Gadkari VV, Zahurancik WJ, Malik CK, Basu AK, and Suo Z*. (2016) Pre-steady-state kinetic investigation of bypass of a bulky guanine lesion by human Y-family DNA polymerases. <em>DNA Repair (Amst.)<\/em>, <strong>46<\/strong>: 20-28.<br \/>\n\u2022\u00a0\u00a0\u00a0Dunn MR, Larsen AC, Zahurancik WJ, Fahmi NE, Meyers M, Suo Z, and Chaput JC*. (2015) DNA polymerase-mediated synthesis of unbiased threose nucleic acid (TNA) polymers requires 7-deazaguanine to suppress G:G mispairing during TNA transcription. <em>J. Am. Chem. Soc.<\/em>, <strong>137<\/strong>: 4014-4017.<br \/>\n\u2022\u00a0\u00a0\u00a0Zahurancik WJ, Baranovskiy AG, Tahirov TH, and Suo Z*. (2015) Comparison of the kinetic parameters of the truncated catalytic subunit and holoenzyme of human DNA polymerase \u0395. <em>DNA Repair (Amst.)<\/em>, <strong>29<\/strong>: 16-22.<br \/>\n\u2022\u00a0\u00a0\u00a0Zahurancik WJ, Klein SJ, and Suo Z*. (2014) Significant contribution of the 3&#8217;\u21925&#8242; exonuclease activity to the high fidelity of nucleotide incorporation catalyzed by human DNA polymerase \u0395. <em>Nucleic Acids Res.<\/em>, <strong>42<\/strong>: 13853-13860.<br \/>\n\u2022\u00a0\u00a0\u00a0Vyas R\u00b0, Zahurancik WJ\u00b0, and Suo Z*. (2014) Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase \u039b. <em>Proc. Natl. Acad. Sci. USA<\/em>, <strong>111<\/strong>: E3033-3042. <strong><em>\u00b0joint first authors<\/em><\/strong><br \/>\n\u2022\u00a0\u00a0\u00a0Zahurancik WJ, Klein SJ, and Suo Z*. (2013) Kinetic mechanism of DNA polymerization catalyzed by human DNA polymerase \u0395. <em>Biochemistry<\/em>, <strong>52<\/strong>: 7041-7049.<br \/>\n\u2022\u00a0\u00a0\u00a0G\u00f6ksenin AY, Zahurancik WJ, LeCompte KG, Taggart DJ, Suo Z, and Pursell ZF*. (2012) Human DNA polymerase \u0395 is able to efficiently extend from multiple consecutive ribonucleotides. <em>J. Biol. Chem.<\/em>, <strong>287<\/strong>: 42675-42684.<br \/>\n\u2022\u00a0\u00a0\u00a0Doddapaneni K, Zahurancik W, Haushalter A, Yuan C, Jackman J, and Wu Z. (2011) RCL hydrolyzes 2&#8242;-deoxyribonucleoside 5&#8242;-monophosphate via formation of a reaction intermediate. <em>Biochemistry<\/em>, <strong>50<\/strong>: 4712-4719.<\/p>\n\t<\/div><!-- .panel__content -->\r\n\r\n<\/div><!-- .panel -->\r\n<div id=\"amoteam-panel-975777406-1573\" class=\"amoteam-panel mfp-hide amoteam-panel-align-right amoteam-panel-pf-image \"\r\n     data-align=\"right\" data-format=\"image\">\r\n\r\n\t<div class=\"amoteam-panel__header\">\r\n\r\n\t\t\r\n\r\n\t\t<button type=\"button\" class=\"amoteam-btn amoteam-btn-rc-square amoteam-btn-panel-close\" data-dismiss=\"modal\" aria-label=\"Close Panel\"><i aria-hidden=\"true\" class=\"amoteam-icon-close\"><\/i><\/button>\r\n\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__img-wrap\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"amoteam-panel__img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2019\/05\/datta.79-e1672849267694.jpg?resize=300%2C321&amp;ssl=1\" data-img-preloaded=\"1\" alt=\"Moulisubhro Datta\">\r\n\t\t\t\t\t<\/div><!-- .panel__img-wrap -->\r\n\r\n\t\t\r\n\t\t<div class=\"amoteam-panel__heading\">\r\n\t\t\t<h3 class=\"amoteam-panel__title amoteam-panel__heading-item\">Moulisubhro Datta<\/h3>\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__subtitle amoteam-panel__heading-item\">Graduate Student<\/div>\r\n\t\t\t\t\t<\/div>\r\n\r\n\t<\/div><!-- .panel__header -->\r\n\r\n\t<div class=\"amoteam-panel__content\">\r\n\t\t\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Email<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0<a href=\"mailto:datta.79@osu.edu\"> datta.79@osu.edu<\/a><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Current Projects<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p>\u2022\u00a0 \u00a0Optimizing chemoenzymatic synthesis of tRNAs and exploring the role of point mutations on tRNAs in onset of disease<br \/>\n<\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Education and Training<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p><strong>Graduate Student \u2013 The Ohio State University (Columbus, OH)<\/strong><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a0Program: Molecular, Cellular, and Developmental Biology (MCDB) Program<\/p>\n<hr \/>\n<p><strong>M.S. &#8211; Indian Institute of Technology (Mumbai, India)<\/strong><\/p>\n<hr \/>\n<p>\u2022\u00a0 Program: Biotechnology<br \/>\n\u2022\u00a0 Advisor: Dr. Anirban Banerjee<\/p>\n<hr \/>\n<p><strong>B.S. \u2013 St. Xavier\u2019s College (Kolkata, India)<br \/>\n<\/strong><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a0Major: Microbiology<\/p>\n<hr \/>\n<p><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\t<\/div><!-- .panel__content -->\r\n\r\n<\/div><!-- .panel -->\r\n<div id=\"amoteam-panel-975777406-2084\" class=\"amoteam-panel mfp-hide amoteam-panel-align-right amoteam-panel-pf-image \"\r\n     data-align=\"right\" data-format=\"image\">\r\n\r\n\t<div class=\"amoteam-panel__header\">\r\n\r\n\t\t\r\n\r\n\t\t<button type=\"button\" class=\"amoteam-btn amoteam-btn-rc-square amoteam-btn-panel-close\" data-dismiss=\"modal\" aria-label=\"Close Panel\"><i aria-hidden=\"true\" class=\"amoteam-icon-close\"><\/i><\/button>\r\n\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__img-wrap\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"amoteam-panel__img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2023\/01\/Rachel-scaled-e1677520154707.jpg?resize=640%2C640&amp;ssl=1\" data-img-preloaded=\"1\" alt=\"Rachel Hemmerlin\">\r\n\t\t\t\t\t<\/div><!-- .panel__img-wrap -->\r\n\r\n\t\t\r\n\t\t<div class=\"amoteam-panel__heading\">\r\n\t\t\t<h3 class=\"amoteam-panel__title amoteam-panel__heading-item\">Rachel Hemmerlin<\/h3>\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__subtitle amoteam-panel__heading-item\">Graduate Student<\/div>\r\n\t\t\t\t\t<\/div>\r\n\r\n\t<\/div><!-- .panel__header -->\r\n\r\n\t<div class=\"amoteam-panel__content\">\r\n\t\t\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Email<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0<a href=\"mailto:hemmerlin.1@osu.edu\"> hemmerlin.1@osu.edu<\/a><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Current Projects<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Education and Training<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p><strong>Graduate Student \u2013 The Ohio State University (Columbus, OH)<\/strong><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a0Program: Chemistry and Biochemistry Graduate Program (Biological Division)<\/p>\n<hr \/>\n<p><strong>B.S. \u2013 Slippery Rock University (Slippery Rock, PA)<br \/>\n<\/strong><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a0Major: Chemistry (Concentration in Biochemistry)<br \/>\n\u2022\u00a0\u00a0\u00a0Advisor: Dr. Ashley M. Loe<\/p>\n<hr \/>\n<p><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\t<\/div><!-- .panel__content -->\r\n\r\n<\/div><!-- .panel -->\r\n<div id=\"amoteam-panel-975777406-2348\" class=\"amoteam-panel mfp-hide amoteam-panel-align-right amoteam-panel-pf-image \"\r\n     data-align=\"right\" data-format=\"image\">\r\n\r\n\t<div class=\"amoteam-panel__header\">\r\n\r\n\t\t\r\n\r\n\t\t<button type=\"button\" class=\"amoteam-btn amoteam-btn-rc-square amoteam-btn-panel-close\" data-dismiss=\"modal\" aria-label=\"Close Panel\"><i aria-hidden=\"true\" class=\"amoteam-icon-close\"><\/i><\/button>\r\n\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__img-wrap\">\r\n\t\t\t\t\t\t\t<img decoding=\"async\" class=\"amoteam-panel__img\" src=\"https:\/\/i0.wp.com\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2025\/08\/Screenshot-2025-08-12-155436-e1768927168408.png?resize=340%2C370&amp;ssl=1\" data-img-preloaded=\"1\" alt=\"Kumar Vaibhav\">\r\n\t\t\t\t\t<\/div><!-- .panel__img-wrap -->\r\n\r\n\t\t\r\n\t\t<div class=\"amoteam-panel__heading\">\r\n\t\t\t<h3 class=\"amoteam-panel__title amoteam-panel__heading-item\">Kumar Vaibhav<\/h3>\r\n\t\t\t\t\t\t<div class=\"amoteam-panel__subtitle amoteam-panel__heading-item\">Graduate Student<\/div>\r\n\t\t\t\t\t<\/div>\r\n\r\n\t<\/div><!-- .panel__header -->\r\n\r\n\t<div class=\"amoteam-panel__content\">\r\n\t\t\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Email<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0<a href=\"mailto:vaibhav.3@buckeyemail.osu.edu\">vaibhav.3@buckeyemail.osu.edu<\/a><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Current Projects<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\r\n<div class=\"amoteam-panel-sc amoteam-sc-text-block  amoteam-panel-sc-only-title\">\r\n\r\n\t<div class=\"amoteam-panel-sc__header amoteam-sc-text-block__header\">\r\n\t\t<h5 class=\"amoteam-panel-sc_title amoteam-sc-text-block_title\">Education and Training<\/h5>\r\n\r\n\t\t\r\n\t<\/div><!-- .sc-text-block__header -->\r\n\r\n\t<div class=\"amoteam-panel-sc__content amoteam-sc-text-block__content\"><\/p>\n<hr \/>\n<p><strong>Graduate Student \u2013 The Ohio State University (Columbus, OH)<\/strong><\/p>\n<hr \/>\n<p>\u2022\u00a0\u00a0\u00a0Program: Biophysics Graduate Program (Biological Division)<\/p>\n<hr \/>\n<p><strong>M.S. \u2013 University of Patna<br \/>\n<\/strong><\/p>\n<p><strong>B.S. &#8211; IISER Thiruvananthapuram<\/strong><\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n<p><\/div>\r\n\r\n<\/div><!-- .sc-text-block -->\n\t<\/div><!-- .panel__content -->\r\n\r\n<\/div><!-- .panel --><\/div><!-- .panels -->\n<h2 style=\"text-align: center;\">&nbsp;<\/h2>\n<hr>\n<h2 style=\"text-align: center;\"><strong>Undergraduate Students<br \/>\n<\/strong><\/h2>\n<hr>\n<div class=\"tmm tmm_undergraduate-students\"><div class=\"tmm_2_columns tmm_wrap tmm_plugin_f\"><span class=\"tmm_two_containers_tablet\"><\/span><div class=\"tmm_container\"><div class=\"tmm_member\" style=\"border-top:#333333 solid 5px;\"><div class=\"tmm_photo tmm_pic_undergraduate-students_0\" style=\"background: url(https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2025\/01\/IMG_6895-scaled-e1736450991540.jpg); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Alexander<\/span> <span class=\"tmm_lname\">Baumgardner<\/span><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><div class=\"tmm_member\" style=\"border-top:#333333 solid 5px;\"><div class=\"tmm_photo tmm_pic_undergraduate-students_1\" style=\"background: url(https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2025\/01\/IMG_6897-scaled.jpg); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Ben<\/span> <span class=\"tmm_lname\">Owens<\/span><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><span class=\"tmm_two_containers_tablet\"><\/span><\/div><span class=\"tmm_columns_containers_desktop\"><\/span><div class=\"tmm_container\"><div class=\"tmm_member\" style=\"border-top:#333333 solid 5px;\"><div class=\"tmm_photo tmm_pic_undergraduate-students_2\" style=\"background: url(https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2025\/01\/IMG_6899-scaled.jpg); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Erica<\/span> <span class=\"tmm_lname\">Popa<\/span><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><div class=\"tmm_member\" style=\"border-top:#333333 solid 5px;\"><div class=\"tmm_photo tmm_pic_undergraduate-students_3\" style=\"background: url(https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-content\/uploads\/2025\/09\/Toby-scaled.jpeg); margin-left: auto; margin-right:auto; background-size:cover !important;\"><\/div><div class=\"tmm_textblock\"><div class=\"tmm_names\"><span class=\"tmm_fname\">Toby<\/span> <span class=\"tmm_lname\">Bomser<\/span><\/div><div class=\"tmm_scblock\"><\/div><\/div><\/div><div style=\"clear:both;\"><\/div><\/div><\/div><\/div>\n<h5 style=\"text-align: center;\"><strong>Webmasters:<\/strong> &nbsp;<a href=\"mailto:datta.79@osu.edu\">Moulisubhro Datta<\/a>, <a href=\"mailto:zahurancik.2@osu.edu\">Walter Zahurancik<\/a><br \/>\n<strong>Web Design:<\/strong> <a href=\"mailto:lai.231@osu.edu\">Stella Lai<\/a><\/h5>\n","protected":false},"excerpt":{"rendered":"<p>Current Members &nbsp; Undergraduate Students Webmasters: &nbsp;Moulisubhro Datta, Walter Zahurancik Web Design: Stella Lai<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"class_list":["post-784","page","type-page","status-publish","hentry","post-preview"],"jetpack_shortlink":"https:\/\/wp.me\/P8Lmk8-cE","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/pages\/784","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/comments?post=784"}],"version-history":[{"count":35,"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/pages\/784\/revisions"}],"predecessor-version":[{"id":2274,"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/pages\/784\/revisions\/2274"}],"wp:attachment":[{"href":"https:\/\/research.cbc.osu.edu\/gopalan.5\/wp-json\/wp\/v2\/media?parent=784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}