{"id":61,"date":"2014-08-03T21:23:06","date_gmt":"2014-08-04T01:23:06","guid":{"rendered":"https:\/\/research.cbc.osu.edu\/nagib.1\/?page_id=61"},"modified":"2026-03-26T12:41:30","modified_gmt":"2026-03-26T16:41:30","slug":"publications","status":"publish","type":"page","link":"https:\/\/research.cbc.osu.edu\/nagib.1\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\t\t
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PubMed<\/a> \u2022 Google Scholar<\/a><\/p>
\u00a0<\/td>Key Publications<\/strong> (Graphic Summary):<\/td><\/tr>
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\"\"<\/td> Skeletal editing by iron-catalyzed carbene insertion of trichloromethanes <\/a>
<\/strong>Bethany M. DeMuynck,\u2020 Ethan E. Hyland,\u2020 Hojin Kim,\u2020 Victoria L. Menches,\u2020 Anna M. M. Vernier, Zhang Wang, David E. Olson,* Mark D. Levin,*
and David A. Nagib*
Chem,<\/em> 2026<\/strong>, 389<\/em>, 183\u2013189 (open access link<\/a>)<\/td><\/tr>
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\"\"<\/td> Deuterated Cyclopropanation of Alkenes by Iron Catalysis <\/a>
<\/strong>Ilias Khan Rana, Khue N. M. Nguyen, Duong T. Ngo, and David A. Nagib
Org. Lett.,<\/em> 2026<\/strong>, 28<\/em>, 1750\u20131754 (open access link<\/a>)<\/td><\/tr>
\"\"<\/td>Iron-Mediated Methyl Esterification with Dibromomethane<\/a>
<\/strong> Emma K. Ralph, Bethany M. DeMuynck, and David A. Nagib
Synthesis,<\/em> 2026<\/strong>, DOI: 10.1055\/a-2746-2256<\/td><\/tr>
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Special Issue: 2025 Women in Chemistry Award to Dr. Dani Schultz<\/div><\/td><\/tr>
\"\"<\/td> Harnessing carbene polarity: Unified catalytic access to donor, neutral, and acceptor carbenes <\/a><\/strong>
Khue N. M. Nguyen,\u2020 Xueling Mo,\u2020\u00a0Bethany M. DeMuynck,\u2020\u00a0Mohamed Elsayed, Jacob J. A. Garwood, Duong T. Ngo, Ilias Khan Rana, and David A Nagib
Science,<\/em> 2025<\/strong>, 389<\/em>, 183\u2013189 (open access link<\/a>)<\/td><\/tr>
\"Chem\"<\/td> Chiral pyrrolidines via an enantioselective Hofmann-L\u00f6ffler-Freytag reaction <\/a><\/strong>
Pavitra Laohapaisan,\u2020 Ipshita Roy,\u2020 and David A. Nagib
Chem Catalysis,<\/em> 2024<\/strong>, 4<\/em>, 101149\u2013101158 (open access<\/a>)<\/td><\/tr>
\"\"<\/td> Radical Polarity<\/a><\/strong>
Jacob J. A. Garwood, Andrew D. Chen, and David A. Nagib
J. Am. Chem. Soc.,<\/em> 2024<\/strong>, 146<\/em>, 28034\u201328059<\/td><\/tr>
\"\"<\/td> Cyclopropanation with Non-Stabilized Carbenes via Ketyl Radicals<\/a><\/strong>
Duong T. Ngo \u2020, Jacob J. A. Garwood \u2020, and David A. Nagib
J. Am. Chem. Soc.,<\/em> 2024<\/strong>, 146<\/em>, 24009\u201324015<\/td><\/tr>
\"Chem\"<\/td>Cyclopropanation of unactivated alkenes with non-stabilized iron carbenes<\/a><\/strong>
Bethany M. DeMuynck, Lumin Zhang, Emma K. Ralph, and David A. Nagib
Chem,<\/em> 2024<\/strong>, 10<\/em>,\u00a01015\u20131027 (open access<\/a>)<\/td><\/tr>
\"Nature<\/td> Carbonyl cross-metathesis via deoxygenative gem-di-metal catalysis <\/a><\/strong>
Lumin Zhang and David A. Nagib
Nature Chem.<\/em>, 2024<\/strong>, 16, 107\u2013113 (open access<\/a>)<\/td><\/tr>
\"\"<\/td>Carbene reactivity from alkyl and aryl aldehydes <\/a><\/strong>
Lumin Zhang, Bethany M. DeMuynck \u2020, Alyson N. Paneque \u2020, Joy E. Rutherford \u2020, and David A. Nagib
Science,<\/em> 2022<\/strong>, 377<\/em>, 649\u2013654<\/td><\/tr>
\"\"<\/td>\u03b3 C\u2013H Functionalization of Amines via Triple H-Atom Transfer of a Vinyl Sulfonyl Radical Chaperone<\/a><\/strong>
James H. Herbort \u2020, Taylor N. Bednar \u2020, Andrew D. Chen, T. V. RajanBabu, and David A. Nagib
J. Am. Chem. Soc.,<\/em> 2022<\/strong>, 144<\/em>, 13366\u201313373<\/td><\/tr>
\"\"<\/td> Radical Aza-Heck Cyclization of Imidates via Energy Transfer, Electron Transfer, and Cobalt Catalysis<\/a><\/strong>
Allen F. Prusinowski, Henry C. Sise, Taylor N. Bednar, and David A. Nagib
ACS Catal.,<\/em> 2022<\/strong>, 12<\/em>, 4327\u22124332<\/td><\/tr>
\"Chem\"<\/td> Aza-heterocycles via copper-catalyzed, remote C\u2013H desaturation of amines<\/a><\/strong>
Leah M. Stateman \u2020, Ross M. Dare \u2020, Alyson N. Paneque, and David A. Nagib
Chem,<\/em> 2022<\/strong>, 8<\/em>, 210\u2013224 (open access<\/a>)<\/td><\/tr>
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\"JACS\"<\/td> Cross-Selective Aza-Pinacol Coupling via Atom Transfer Catalysis<\/a><\/strong>
Sean M. Rafferty \u2020, Joy E. Rutherford \u2020, Lumin Zhang, Lu Wang, and David A. Nagib
J. Am. Chem. Soc.,<\/em> 2021<\/strong>, 143<\/em>, 5622\u20135628<\/td><\/tr>
\"\"<\/td> Regioselective Radical Amino-Functionalizations of Allyl Alcohols via Dual Catalytic Cross-Coupling<\/a><\/strong>
Zuxiao Zhang, Duong T. Ngo, and David A. Nagib
ACS Catal.,<\/em> 2021<\/strong>, 11<\/em>, 3473\u22123477<\/td><\/tr>
\"Nature<\/td>Enantioselective Radical C\u2013H Amination for the Synthesis of \u03b2-Amino Alcohols<\/a><\/strong>
Kohki M. Nakafuku \u2020, Zuxiao Zhang \u2020, Ethan A. Wappes \u2020, Leah M. Stateman, Andrew D. Chen, and David A. Nagib
Nature Chem.,<\/em> 2020<\/strong>, 12<\/em>, 697\u2013704 (open access<\/a>)<\/td><\/tr>
\"JACS\"<\/td>Vicinal, Double C\u2013H Functionalization of Alcohols via an Imidate Radical-Polar Crossover Cascade<\/a><\/strong>
Allen F. Prusinowski, Raymond K. Twumasi, Ethan A. Wappes, and David A. Nagib
J. Am. Chem. Soc.,<\/em> 2020<\/strong>,\u00a0142<\/em>, 5429\u22125438<\/td><\/tr>
\"\"<\/td>Radical Cascade Synthesis of Azoles via Tandem Hydrogen Atom Transfer<\/a><\/strong>
Andrew D. Chen \u2020, James H. Herbort \u2020, Ethan A. Wappes, Kohki M. Nakafuku, Darsheed N. Mustafa, and David A. Nagib
Chem. Sci.,<\/em> 2020<\/strong>,\u00a011<\/em>, 2479\u22122486<\/td><\/tr>
\"\"<\/td>Chiral Piperidines from Acyclic Amines via Enantioselective, Radical-Mediated \u03b4 C\u2013H Cyanation<\/a><\/strong>
Zuxiao Zhang, Xin Zhang, and David A. Nagib
Chem,<\/em> 2019<\/strong>, 5<\/em>, 3127\u22123134\u00a0\u00a0(<\/span>Open Access\u00a0Pre-Print<\/a>)<\/span><\/td><\/tr>
\"\"<\/td>Development of an Imine Chaperone for Selective C\u2013H Functionalization of Alcohols via Radical Relay<\/a><\/strong>
Kohki M. Nakafuku \u2020, Raymond K. Twumasi \u2020, Avassaya Vanitcha \u2020, Ethan A. Wappes, Kayambu Namitharan, Mathieu Bekkaye, and David A. Nagib
J. Org. Chem.,<\/em> 2019<\/strong>, 84<\/em>, 13065\u221213072<\/td><\/tr>
\"\"<\/td>Multi-component Heteroarene Couplings via Polarity-reversed Radical Cascades<\/a><\/strong>
Jeremy M. Lear \u2020, J. Quentin Buquoi \u2020, Xin Gu, Kui Pan, Darsheed N. Mustafa, and David A. Nagib
Chem. Commun.,<\/em> 2019<\/strong>, 55<\/em>, 8820\u22128823<\/td><\/tr>
\"\"<\/td> Heteroarene Phosphinylalkylation via a Catalytic, Polarity-Reversing Radical Cascade<\/a><\/strong>
J. Quentin Buquoi \u2020, Jeremy M. Lear \u2020, Xin Gu, and David A. Nagib
ACS Catal.,<\/em> 2019<\/strong>, 9<\/em>, 5330\u22125335<\/td><\/tr>
\"\"<\/td>Catalytic \u03b2 C\u2013H amination via an imidate radical relay<\/a><\/strong>
Leah M. Stateman, Ethan A. Wappes, Kohki M. Nakafuku, Kara M. Edwards, and David A. Nagib
Chem. Sci.,<\/em> 2019<\/strong>, 10<\/em>, 2693\u22122699<\/td><\/tr>
\"\"<\/td> Site-Selective C\u2013H Functionalization of (Hetero)Arenes via Transient, Non-symmetric Iodanes<\/a><\/strong>
Stacy C. Fosu \u2020, Chido M. Hambira \u2020, Andrew D. Chen, James R. Fuchs, and David A. Nagib
Chem,<\/em> 2019<\/strong>, 5<\/em>, 417\u2212428 (Open Access<\/a>)<\/td><\/tr>
\"\"<\/td>\u03b4 C\u2212H (Hetero)Arylation via Cu-Catalyzed Radical Relay<\/a><\/strong>
Zuxiao Zhang, Leah M. Stateman, and David A. Nagib
Chem. Sci.,<\/em> 2019<\/strong>, 10<\/em>,\u00a01207\u22121211<\/td><\/tr>
\"\"<\/td> Ketyl radical reactivity via atom transfer catalysis<\/a><\/strong>
Lu Wang, Jeremy M. Lear, Sean M. Rafferty, Stacy C. Fosu and David A. Nagib
Science,<\/em> 2018<\/strong>, 362<\/em>, 225\u2212229 (open access<\/a>)<\/td><\/tr>
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Highlighted<\/a> in Science,\u00a0<\/em>“Easy access to elusive radical reactions” by Blackburn and Roizen,\u00a0Science,<\/em> 2018<\/strong>,\u00a0362<\/em>, 157\u2212158<\/div>
\"JACS\"<\/td>Catalytic Alkene Difunctionalization via Imidate Radicals<\/a><\/strong>
Kohki M. Nakafuku \u2020, Stacy C. Fosu \u2020, and David A. Nagib
J. Am. Chem. Soc.,<\/em> 2018<\/strong>, 140<\/em>, 11202\u221211205<\/td><\/tr>
\"\"<\/td>\u03b2 C\u2013H di-halogenation via iterative hydrogen atom transfer<\/a><\/strong>
Ethan A. Wappes \u2020, Avassaya Vanitcha \u2020, and David A. Nagib
Chem. Sci.,<\/em> 2018<\/strong>, 9<\/em>, 4500\u20134504<\/td><\/tr>
\"nature2011\"<\/td>Directed \u03b2 C\u2013H Amination of Alcohols via Radical Relay Chaperones<\/a><\/strong>
Ethan A. Wappes \u2020, Kohki M. Nakafuku \u2020, and David A. Nagib
J. Am. Chem. Soc.,<\/em> 2017<\/strong>,\u00a0139<\/em>, 10204\u201310207<\/td><\/tr>
<\/td>Triiodide-Mediated \u03b4-Amination of Secondary C-H Bonds<\/a><\/strong>
Ethan A. Wappes, Stacy C. Fosu, Trevor C. Chopko, and David A. Nagib
Angew. Chem. Int. Ed.,<\/em> 2016<\/strong>, 55<\/em>, 9974\u20139978<\/td><\/tr>
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Highlighted<\/a> in Synform, featured as cover<\/a> article, Nov 2016<\/em><\/div>
Highlighted<\/a> in Organic Chemistry Portal, Sept 2017<\/em><\/div>
> 200\u00a0citations<\/em><\/a><\/div><\/td><\/tr><\/tbody><\/table>

Reviews<\/b><\/p>
\"\"<\/td>Remote C\u2013H Functionalization via Selective Hydrogen Atom Transfer<\/a><\/strong>
Leah M. Stateman, Kohki M. Nakafuku, and David A. Nagib
Synthesis,<\/em> 2018<\/strong>, 50<\/em>, 1569\u20131586<\/td><\/tr>
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An essential guide to selective C-H functionalization by radicals (for experts\u00a0and beginners alike)<\/i><\/div><\/td><\/tr>
\"\"<\/td>(Z<\/em>)-N-Phenoxybenzimidoyl Chloride<\/a><\/strong>
Ross M. Dare, and David A. Nagib
Encyclopedia of Reagents for Organic Synthesis (e-EROS),<\/em> 2022<\/strong>, DOI: 10.1002\/047084289X.rn02431<\/td><\/tr>
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Explores the many uses of our imidate radical chaperone<\/i><\/div><\/td><\/tr><\/tbody><\/table>

Perspectives &\u00a0Highlights<\/strong><\/b><\/p>

Radical arenes<\/a>
<\/a>Taylor N. Bender and David A. Nagib
Nature Chem.,<\/em> 2023<\/strong>,\u00a0<\/em>15<\/em>, 3\u20134<\/p>

Asymmetric Catalysis in Radical Chemistry<\/a>
<\/a>David A. Nagib
Chem. Rev.,<\/em> 2022<\/strong>,\u00a0122<\/em>, 15989\u201315992<\/p>

Nitrogen gets radical<\/a>
<\/a>David A. Nagib
Nature Chem.,<\/em> 2019<\/strong>,\u00a011<\/em>, 396\u2013398<\/p>

Radical Conversion of Acids to Alkenes via Dual Catalysis<\/a>
Allen F. Prusinowski and David A. Nagib
Trends in Chemistry,<\/em> 2019<\/strong>,\u00a01,\u00a0<\/em>452-453<\/p>

Catalytic Desymmetrization by C-H Functionalization as a Solution to the Chiral Methyl Problem<\/a>
David A. Nagib
Angew. Chem. Int. Ed.,<\/em> 2017<\/strong>,\u00a056,<\/em> 7354\u20137356<\/p>

Catalytic, Asymmetric Alkylation via Excited-State Iminium Ions<\/a>
David A. Nagib
Chem,<\/em> 2017<\/strong>,\u00a02<\/em>, 616\u2013618<\/p>

Pre-OSU<\/strong><\/p>
\"nature2011\"<\/td>Seven Post-Synthetic Covalent Reactions in Tandem Leading to Enzyme-Like Complexity within Metal-Organic Framework Crystals<\/a><\/strong>
Alejandro M. Fracaroli, Peter Siman, David A. Nagib, Mitsuharu Suzuki, Hiroyasu Furukawa, F. Dean Toste, and Omar M. Yaghi
J. Am. Chem. Soc.,<\/em> 2016<\/strong>,\u00a0138<\/em>, 8352\u20138355<\/td><\/tr>
\"nature2011\"<\/td>Trifluoromethylation of Arenes and Heteroarenes by Means of Photoredox Catalysis<\/a>
David A. Nagib\u00a0&\u00a0David\u00a0W. C. MacMillan
Nature,<\/em> 2011<\/strong>,\u00a0480<\/em>, 224\u2013228<\/td><\/tr>
\"AngewCover2\"<\/td>Photoredox Catalysis:\u00a0A Mild, Operationally Simple Approach to the Synthesis of \u03b1-Trifluoromethyl Carbonyl Compounds
<\/a>Phong V. Pham, David A. Nagib, David W. C. MacMillan
Angew. Chem. Int. Ed.,<\/em> 2011<\/strong>,\u00a050<\/em>, 6119\u20136122<\/td><\/tr>
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Selected as a \u201cHot Paper\u201d by the editors of ACIE
<\/em><\/em>>400 citations<\/em><\/em><\/a><\/p><\/div><\/td><\/tr>

\"JACS\"<\/td>Enantioselective \u03b1-Trifluoromethylation of Aldehydes via Photoredox Organocatalysis<\/a>
David A. Nagib, Mark\u00a0E. Scott, David W. C. MacMillan
J. Am. Chem. Soc.<\/em>, 2009<\/strong>,\u00a0131,<\/em> 10875\u201310877<\/td><\/tr>
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Most downloaded synthetic methods article in JACS for all of 2009
>1000\u00a0citations<\/a>
<\/em><\/div>
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<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

PubMed \u2022 Google Scholar \u00a0 Key Publications (Graphic Summary): \u00a0 Skeletal editing by iron-catalyzed carbene insertion of trichloromethanes Bethany M. DeMuynck,\u2020 Ethan E. Hyland,\u2020 Hojin Kim,\u2020 Victoria L. Menches,\u2020 Anna M. M. Vernier, Zhang Wang, David E. Olson,* Mark D. Levin,*and David A. Nagib*Chem, 2026, 389, 183\u2013189 (open access link) \u00a0\u00a0 Deuterated Cyclopropanation of Alkenes […]<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-61","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/research.cbc.osu.edu\/nagib.1\/wp-json\/wp\/v2\/pages\/61","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/research.cbc.osu.edu\/nagib.1\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/research.cbc.osu.edu\/nagib.1\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/research.cbc.osu.edu\/nagib.1\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/research.cbc.osu.edu\/nagib.1\/wp-json\/wp\/v2\/comments?post=61"}],"version-history":[{"count":626,"href":"https:\/\/research.cbc.osu.edu\/nagib.1\/wp-json\/wp\/v2\/pages\/61\/revisions"}],"predecessor-version":[{"id":3038,"href":"https:\/\/research.cbc.osu.edu\/nagib.1\/wp-json\/wp\/v2\/pages\/61\/revisions\/3038"}],"wp:attachment":[{"href":"https:\/\/research.cbc.osu.edu\/nagib.1\/wp-json\/wp\/v2\/media?parent=61"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}