{"id":78,"date":"2012-09-15T20:59:32","date_gmt":"2012-09-15T20:59:32","guid":{"rendered":"http:\/\/research.chemistry.ohio-state.edu\/wysocki\/?page_id=78"},"modified":"2024-12-03T13:46:11","modified_gmt":"2024-12-03T18:46:11","slug":"publications","status":"publish","type":"page","link":"https:\/\/research.cbc.osu.edu\/wysocki.11\/group-home\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Most Recent Publications First<\/strong><\/span><\/p>\n

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Wang, Q.; <\/span><\/span>Wang, Q.; <\/span><\/span>Qi, Z.; <\/span><\/span>Moeller, W.; <\/span><\/span>Wysocki<\/i>, V.H.; <\/span><\/span>Sun, L. “<\/em><\/span>Native Proteomics by Capillary Zone Electrophoresis-Mass Spectrometry.” Angewandte Chemie. 2024, <\/strong><\/em>Volume136<\/span>,\u00a0Issue48. DOI: 10.1002\/ange.202408370. [Request reprint \u00a9 (pdf)]<\/a><\/span><\/p>\n

Shaw, J. B.; Harvey, S. R.; Du, C.; Xu, Z.; Edgington, R. M.; Olmedillas, E.; Saphire, E. O.; Wysocki, V. H. Protein Complex Heterogeneity and Topology Revealed by Electron Capture Charge Reduction and Surface Induced Dissociation. ACS Cent. Sci.<\/em> 2024<\/strong>, 10<\/em> (8), 1537\u20131547. DOI: 10.1021\/acscentsci.4c00461. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Li, Y.; Shen, Z.; Zhang, M.; Yang, X.-Y.; Cleary, S. P.; Xie, J.; Marathe, I. A.; Kostelic, M.; Greenwald, J.; Rish, A. D.; Wysocki, V. H.; Chen, C.; Chen, Q.; Fu, T.-M.; Yu, Y. “PtuA and PtuB Assemble into an Inflammasome-like Oligomer for Anti-Phage Defense.” Nat Struct Mol Biol<\/em> 2024<\/strong>, 31<\/em> (3), 413\u2013423. DOI: 10.1038\/s41594-023-01172-8. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Roy, J.; Marathe, I.; Wysocki, V.; Pradeep, T. “Observing Atomically Precise Nanocluster Aggregates in Solution by Mass Photometry.” Chem. Commun.<\/em> 2024<\/strong>, 60<\/em> (52), 6655\u20136658. DOI: 10.1039\/D4CC00363B. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

McElroy, C. A.; Ihms, E. C.; Kumar Yadav, D.; Holmquist, M. L.; Wadhwa, V.; Wysocki, V. H.; Gollnick, P.; Foster, M. P. “Solution Structure, Dynamics and Tetrahedral Assembly of Anti-TRAP, a Homo-Trimeric Triskelion-Shaped Regulator of Tryptophan Biosynthesis in Bacillus Subtilis<\/em>.” Journal of Structural Biology: X<\/em> 2024<\/strong>, 10<\/em>, 100103. DOI: 10.1016\/j.yjsbx.2024.100103. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n<\/div>\n

Panczyk, E. M.; Lin, Y.-F.; Harvey, S.R.; Snyder, D.T.; Liu, F. C.; Ridgeway, M.E.; Park, M.A.; Bleiholder, C.; Wysocki V.H. “Evaluation of a Commercial TIMS-Q-TOF Platform for Native Mass Spectrometry.” Journal of the American Society for Mass Spectrometry<\/cite> 2024<\/strong>\u00a035<\/em>\u00a0(7), 1394-1402. <\/strong>DOI: 10.1021\/jasms.3c00320 [Request reprint \u00a9 (pdf)]<\/a><\/div>\n<\/div>\n
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Zakharova, K.; Liu, M.; Greenwald, J. R.; Caldwell, B. C.; Qi, Z.; Wysocki, V. H.; Bell, C. E. “Structural Basis for the Interaction of Red\u03b2 Single-Strand Annealing Protein with Escherichia Coli<\/i> Single-Stranded DNA-Binding Protein.” Journal of Molecular Biology<\/i> 2024<\/strong>, 436<\/i> (11), 168590. DOI: 10.1016\/j.jmb.2024.168590. [Request reprint \u00a9 (pdf)]<\/a><\/div>\n
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Yang, X.-Y.; Shen, Z.; Xie, J.; Greenwald, J.; Marathe, I.; Lin, Q.; Xie, W. J.; Wysocki, V. H.; Fu, T.-M. “Molecular Basis of Gabija Anti-Phage Supramolecular Assemblies.” Nat Struct Mol Bi<\/i>ol <\/em>2024<\/strong>.<\/em> DOI: 10.1038\/s41594-024-01283-w. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

Witzel, M. T.; Veltri, L. M.; Kostelic, M.; Elshamy, Y. S.; Lucas, J. A.; Lai, S.; Du, C.; Wysocki, V. H.; Holland, L. A. “Protein Analysis Using Capillary Electrophoresis Coupled to Mass Spectrometry through Vibrating Sharp-Edge Spray Ionization.” ELECTROPHORESIS <\/i>2024<\/strong>. DOI: 10.1002\/elps.202300298. [Request reprint \u00a9 (pdf)]<\/a><\/div>\n
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Harvey, S. R.; Gadkari, V.V.; Ruotolo, B.T.; Russell, D.H.; Wysocki, V.H.; Zhou, M. “Expanding Native Mass Spectrometry to the Masses.”Journal of the American Society for Mass Spectrometry<\/cite>\u00a02024<\/strong>\u00a035<\/em> (3), 646-652. DOI: 10.1021\/jasms.3c00352. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n<\/div>\n

Harris, R.A.; May, J.C.; Harvey, S.R.; Wysocki, V.H.; McLean, J.A. “Evaluation of Surface-Induced Dissociation Ion Mobility-Mass Spectrometry for Lipid Structural Characterization. “Journal of the American Society for Mass Spectrometry<\/cite>\u00a02024<\/strong>\u00a035<\/em> (2), 214-223. DOI: 10.1021\/jasms.3c00319. [Request reprint \u00a9 (pdf)]<\/a><\/div>\n
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Walker, T.; Sun, H.M.; Gunnels, T.; Wysocki, V.; Laganowsky, S.; Rye, H.; Russell. D.”Dissecting the Thermodynamics of ATP Binding to GroEL One Nucleotide at a Time.” ACS Central Science<\/cite>\u00a02023\u00a09<\/em> (3), 466-475. DOI: 10.1021\/acscentsci.2c01065.\u00a0[Request reprint \u00a9 (pdf)]<\/a><\/div>\n
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Du, C.; Cleary, S. P.; Kostelic, M.M.; Jones, B.J.; Kafader, J.O.; Wysocki, V.H. “Combining Surface-Induced Dissociation and Charge Detection Mass Spectrometry to Reveal the Native Topology of Heterogeneous Protein Complexes.” Analytical Chemistry<\/cite>\u00a02023\u00a095<\/em> (37), 13889-13896. DOI: 10.1021\/acs.analchem.3c02185.\u00a0[Request reprint \u00a9 (pdf)]<\/a><\/p>\n<\/div>\n

Jia, M.; Song, Y.; Du, C.; Wysocki, V. H. “Oxidized and Reduced Dimeric Protein Complexes Illustrate Contrasting CID and SID Charge Partitioning.” Journal of the American Society for Mass Spectrometry<\/cite> Article 2023<\/strong>\u00a034<\/em>\u00a0(10), 2166-2175. DOI: 10.1021\/jasms.3c00142<\/span>\u00a0[Request reprint \u00a9 (pdf)]<\/a><\/div>\n
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Kovvali, S.;<\/span>\u00a0Gao, Y.;<\/span>\u00a0Cool, A.;<\/span>\u00a0Lindert, S.;<\/span>\u00a0Wysocki, V.H.;<\/span>\u00a0Bell, C.E.;<\/span> Gopalan, V.\u00a0 “Insights into the catalytic mechanism of a bacterial deglycase essential for utilization of fructose-lysine”<\/span>.\u00a0Protein Science<\/i>\u00a02023,<\/span>\u00a032<\/span>(\u00a07<\/span>):e4695. DOI:10.1002\/pro.4695. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Kreutzer, A. G.; Guaglianone, G.; Yoo, S.; Parrocha, C. M. T.; Ruttenberg, S. M.; Malonis, R. J.; Tong, K.; Lin, Y.-F.; Nguyen, J. T.; Howitz, W. J.; Diab, M. N.; Hamza, I. L.; Lai, J. R.; Wysocki, V. H.; Nowick, J. S. “Probing differences among A\u03b2 oligomers with two triangular trimers derived from A\u03b2”. PNAS 2023, 120 (22) e2219216120.<\/em> DOI: 10.1073\/pnas.2219216120. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Jimenez-Harrison, D.; Huseby, C. J.; Hoffman, C. N.; Sher, S.; Snyder, D.; Seal, B.; Yuan, C.; Fu, H.; Wysocki, V.; Giorgini, F.; Kuret, J.\u00a0 “DJ-1 Molecular Chaperone Activity Depresses Tau Aggregation Propensity through Interaction with Monomers”. Biochemistry<\/i> 2023, 62<\/i> (5), 976\u2013988. DOI: 10.1021\/acs.biochem.2c00581. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n

Bermeo, S.; Favor, A.; Chang, Y.; Norris, A.; Boyken, S.; Hsia, Y.; Haddox, H. K.; Xu, C.; Brunette, T.j.; Wysocki, V.; Bhabha, G.; Ekiert, D.C.; Baker, D.;\u00a0 \u201cDe Novo Design of Obligate ABC-Type Heterotrimeric Proteins.\u201d Nature Structural & Molecular Biology<\/em> 2022, 29(12), 1266\u201376. DOI: 10.1038\/s41594-022-00879-4. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Boulanger<\/span><\/span>, E.F.; <\/span>Sabag-Daigle<\/span><\/span>, A.; <\/span>Baniasad<\/span><\/span>, M.;<\/span>\u00a0Kokkinias<\/span><\/span>, K.; <\/span>Schwieters<\/span><\/span>, A.;<\/span>\u00a0Wrighton<\/span><\/span>, K.C.; <\/span>Wysocki<\/span><\/span>, V.H.; <\/span>\u00a0Ahmer<\/span>ahmer, B.M.M. “Sugar-Phosphate Toxicities Attenuate Salmonella Fitness in the Gut. “Journal of Bacteriology, 2022, e00344-22,204, 12. DOI: 10.1128\/jb.00344-22. [Request reprint \u00a9 (pdf)]<\/a><\/span><\/p>\n

Sarni, S.; Roca, J.; Du, C; Jia, M.; Li, H.; Damjanovic, A.; Matecka, E.M.; Wysocki, V.; Woodson, S.A.; \u201cIntrinsically Disordered Interaction Network in an RNA Chaperone Revealed by Native Mass Spectrometry.\u201d Proceedings of the National Academy of Sciences<\/em> 2022 119(47). DOI: 10.1073\/pnas.2208780119. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Thirugnanasambantham, P.; Kovvali, S.; Cool, A.; Gao, Y.; Sabag-Daigle, A.; Boulanger, E.F.; Mitton-Fry, M.; Capua, A.D.; Behrman, E.J.; Wysocki, V.H.; Lindert, S.; Ahmer, B.M.M.; Gopalan, V. \u201cSerendipitous Discovery of a Competitive Inhibitor of FraB, a Salmonella Deglycase and Drug Target.\u201d Pathogens<\/em> 2022, 11(10), 1102. DOI: 10.3390\/pathogens11101102. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Caldwell, B. J.; Norris, A. S.; Karbowski, C. F.; Wiegand, A. M.; Wysocki, V. H.; Bell, C. E. Structure of a Rect\/Red\u03b2 Family Recombinase in Complex with a Duplex Intermediate of DNA Annealing. Nature Communications<\/em> 2022, 13 (1). [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Li, W. ; Norris, A.S; Lichententhal K.; Kelly, S. ; Ihms, E. C. ; Gollnick P. ; Wysocki, V.H. ; Foster, M. P. Thermodynamic Coupling between Neighboring Binding Sites in Homo\u2010Oligomeric Ligand Sensing Proteins from Mass Resolved Ligand\u2010Dependent Population Distributions. Protein Science <\/i>2022 31, (10)\u00a0 https:\/\/doi.org\/10.1002\/pro.4424.\u00a0\u00a0 [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Marciano, S.; Dey, D.; Listov, D.; Fleishman, S. J.; Sonn-Segev, A.; Mertens, H.; Busch, F.; Kim, Y.; Harvey, S. R.; Wysocki, V. H.; Schreiber, G. Protein Quaternary Structures in Solution Are a Mixture of Multiple Forms. Chemical Science, 2022,13<\/strong>, 11680-11695 DOI:10.1039\/D2SC02794A. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Turzo, S. M. B. A.;\u00a0 Seffernick, J. T.;\u00a0 Rolland, A. D.;\u00a0 Donor, M. T.;\u00a0 Heinze, S.;\u00a0 Prell, J. S.;\u00a0 Wysocki, V. H.; Lindert, S., Protein shape sampled by ion mobility mass spectrometry consistently improves protein structure prediction. Nature Communications<\/em> 2022, 13 (1), 4377. DOI:10.1038\/s41467-022-32075-9. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Guaglianone, G.;\u00a0 Torrado, B.;\u00a0 Lin, Y.-F.;\u00a0 Watkins, M. C.;\u00a0 Wysocki, V. H.;\u00a0 Gratton, E.; Nowick, J. S., Elucidating the Oligomerization and Cellular Interactions of a Trimer Derived from A\u03b2 through Fluorescence and Mass Spectrometric Studies.\u00a0ACS Chem. Neurosci.<\/i><\/span>\u00a02022<\/span>, 13<\/span>, 16<\/span>, 2473\u20132482<\/span> DOI:10.1021\/acschemneuro.2c00313. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Seffernick, J. T.;\u00a0 Turzo, S. M. B. A.;\u00a0 Harvey, S. R.;\u00a0 Kim, Y.;\u00a0 Somogyi, \u00c1.;\u00a0 Marciano, S.;\u00a0 Wysocki, V. H.; Lindert, S., Simulation of Energy-Resolved Mass Spectrometry Distributions from Surface-Induced Dissociation. Analytical Chemistry<\/em> 2022, 94 (29), 10506-10514. DOI:10.1021\/acs.analchem.2c01869. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Phan, H.-D.;\u00a0 Norris, A. S.;\u00a0 Du, C.;\u00a0 Stachowski, K.;\u00a0 Khairunisa, Bela H.;\u00a0 Sidharthan, V.;\u00a0 Mukhopadhyay, B.;\u00a0 Foster, Mark P.;\u00a0 Wysocki, Vicki H.; Gopalan, V., Elucidation of structure\u2013function relationships in Methanocaldococcus jannaschii RNase P, a multi-subunit catalytic ribonucleoprotein. Nucleic Acids Research<\/em> 2022, 50 (14), 8154-8167. DOI:10.1093\/nar\/gkac595. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Harvey, S. R.;\u00a0 Ben-Nissan, G.;\u00a0 Sharon, M.; Wysocki, V. H., Surface-Induced Dissociation for Protein ComplexProtein complexes Characterization. In Proteoform Identification: Methods and Protocols, Sun, L.; Liu, X., Eds. Springer US: New York, NY, 2022; pp 211-237. DOI:10.1007\/978-1-0716-2325-1. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Geiser, D. L.;\u00a0 Li, W.;\u00a0 Pham, D. Q. D.;\u00a0 Wysocki, V. H.; Winzerling, J. J., Shotgun and TMT-Labeled Proteomic Analysis of the Ovarian Proteins of an Insect Vector, Aedes aegypti (Diptera: Culicidae). Journal of Insect Science<\/em> 2022, 22 (2), 7. DOI:10.1093\/jisesa\/ieac018. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Szkoda, B. E.; Di Capua, A.; Shaffer, J.; Behrman, E. J.; Wysocki, V. H.; Gopalan, V., Characterization of a Salmonella Transcription Factor-DNA Complex and Identification of the Inducer by Native Mass Spectrometry. Journal of Molecular Biology<\/em> 2022, 434 (7), 167480. DOI:10.1016\/j.jmb.2022.167480. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Stachowski K, Norris AS, Potter D, Wysocki VH, Foster MP. Mechanisms of Cre recombinase synaptic complex assembly and activation illuminated by Cryo-EM. Nucleic Acids Res. 2022 Feb 22;50(3):1753-1769. doi: 10.1093\/nar\/gkac032.\u00a0 [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Harvey, S. R.; O\u2019Neale, C.; Schey, K. L.; Wysocki, V. H., Native Mass Spectrometry and Surface Induced Dissociation Provide Insight into the Post-Translational Modifications of Tetrameric AQP0 Isolated from Bovine Eye Lens. Analytical Chemistry<\/em> 2022, 94 (3), 1515-1519. DOI:10.1021\/acs.analchem.1c04322. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Baniasad, M.; Kim, Y.; Shaffer, M.; Sabag-Daigle, A.; Leleiwi, I.; Daly, R. A.; Ahmer, B. M. M.; Wrighton, K. C.; Wysocki, V. H., Optimization of proteomics sample preparation for identification of host and bacterial proteins in mouse feces. Analytical and Bioanalytical Chemistry<\/em> 2022. 1-15. DOI:10.1007\/s00216-022-03885-z. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Zhang, S.; Yoo, S.; Snyder, D. T.; Katz, B. B.; Henrickson, A.; Demeler, B.; Wysocki, V. H.; Kreutzer, A. G.; Nowick, J. S., A Disulfide-Stabilized A\u03b2 that Forms Dimers but Does Not Form Fibrils. Biochemistry<\/em> 2022. DOI:10.1021\/acs.biochem.1c00739. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Karch, K. R.; Snyder, D. T.; Harvey, S. R.; Wysocki, V. H., Native Mass Spectrometry: Recent Progress and Remaining Challenges. Annual Review of Biophysics<\/span>\u00a02022<\/span>\u00a051<\/span>:1<\/span>,\u00a0157-179. <\/span>DOI:10.1146\/annurev-biophys-092721-085421.\u00a0[Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Zahurancik, W. J.; Norris, A. S.; Lai, S. M.; Snyder, D. T.; Wysocki, V. H.; Gopalan, V., Chapter Four – Purification, reconstitution, and mass analysis of archaeal RNase P, a multisubunit ribonucleoprotein enzyme. Methods in Enzymology<\/em> 2021; Vol. 659, pp 71-103. DOI:10.1016\/bs.mie.2021.07.006. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Lai, S. M.; Thirugnanasambantham, P.; Sidharthan, V.; Norris, A. S.; Law, J. D.; Gopalan, V.; Wysocki, V. H., Chapter Three – Use of tandem affinity\u2013buffer exchange chromatography online with native mass spectrometry for optimizing overexpression and purification of recombinant proteins. Methods in Enzymology<\/em> 2021; Vol. 659, pp 37-70. DOI: 10.1016\/bs.mie.2021.07.007. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Snyder, D. T.; Harvey, S. R.; Wysocki, V. H., Surface-induced Dissociation Mass Spectrometry as a Structural Biology Tool. Chem Rev. 2022 Apr 27;122(8):7442-7487.\u00a0 DOI:10.1021\/acs.chemrev.1c00309. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

McCabe, J.\u00a0W.; Jones, B. J.; Walker, T. E.; Schrader, R. L.; Huntley, A. P.; Lyu, J.; Hoffman, N. M.; Anderson, G. A.; Reilly, P. T. A.; Laganowsky, A.; Wysocki, V. H.; Russell, D. H., Implementing Digital-Waveform Technology for Extended m\/z Range Operation on a Native Dual-Quadrupole FT-IM-Orbitrap Mass Spectrometer. Journal of the American Society for Mass Spectrometry<\/em> 2021, 32 (12), 2812-2820. DOI:10.1021\/jasms.1c00245. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Snyder, D. T.; Jones, B. J.; Lin, Y.-F.; Cooper-Shepherd, D. A.; Hewitt, D.; Wildgoose, J.; Brown, J. M.; Langridge, J. I.; Wysocki, V. H., Surface-induced dissociation of protein complexes on a cyclic ion mobility spectrometer. Analyst<\/em> 2021,146<\/strong>, 6861-6873 DOI:10.1039\/d1an01407b. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Novikova, I. V.; Zhou, M.; Du, C.; Parra, M.; Kim, D. N.; VanAernum, Z. L.; Shaw, J. B.; Hellmann, H.; Wysocki, V. H.; Evans, J. E., Tunable Heteroassembly of a Plant Pseudoenzyme\u2013Enzyme Complex. ACS Chem. Biol.<\/i><\/span>\u00a02021<\/span>, 16<\/span>, 11<\/span>, 2315\u20132325<\/span> DOI:10.1021\/acschembio.1c00475. [Request reprint \u00a9 (pdf)]<\/a>[Cover article]<\/a><\/p>\n

Woodall, N. B.; Weinberg, Z.; Park, J.; Busch, F.; Johnson, R. S.; Feldbauer, M. J.; Murphy, M.; Ahlrichs, M.; Yousif, I.; MacCoss, M. J.; Wysocki, V. H.; El-Samad, H.; Baker, D., De novo design of tyrosine and serine kinase-driven protein switches. Nature Structural & Molecular Biology.<\/em> 2021, 28 (9), 762-770. DOI:10.1038\/s41594-021-00649-8. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Marathe, I. A.; Lai, S. M.; Zahurancik, W. J.; Poirier, M. G.; Wysocki, Vicki H.; Gopalan, V., Protein cofactors and substrate influence Mg2+-dependent structural changes in the catalytic RNA of archaeal RNase P. Nucleic Acids Research<\/em>. 2021. gkab655. DOI:10.1093\/nar\/gkab655. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Baniasad, M.; Reed, A. J.; Lai, S. M.; Zhang, L.; Schulte, K. Q.; Smith, A. R.; LeSassier, D. S.; Weber, K. L.; Hewitt, F. C.; Woerner, A. E.; Gardner, M. W.; Wysocki, V. H.; Freitas, M. A., Optimization of proteomics sample preparation for forensic analysis of skin samples. Journal of Proteomics<\/em>. 2021, 249, 104360. DOI:10.1016\/j.jprot.2021.104360. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Busch, F.; VanAernum, Z. L.; Lai, S. M.; Gopalan, V.; Wysocki, V. H., Analysis of Tagged Proteins Using Tandem Affinity-Buffer Exchange Chromatography Online with Native Mass Spectrometry. Biochemistry<\/em>. 2021, 60 (24), 1876-1884. DOI:10.1021\/acs.biochem.1c00138. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Vulovic, I.; Yao, Q.; Park, Y.-J.; Courbet, A.; Norris, A.; Busch, F.; Sahasrabuddhe, A.; Merten, H.; Sahtoe, D. D.; Ueda, G.; Fallas, J. A.; Weaver, S. J.; Hsia, Y.; Langan, R. A.; Pl\u00fcckthun, A.; Wysocki, V. H.; Veesler, D.; Jensen, G. J.; Baker, D., Generation of ordered protein assemblies using rigid three-body fusion. Proceedings of the National Academy of Sciences<\/em>. 2021, 118 (23), e2015037118. DOI:10.1073\/pnas.2015037118. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Koenig, M. J.; Agana, B. A.; Kaufman, J. M.; Sharpnack, M. F.; Wang, W. Z.; Weigel, C.; Navarro, F. C. P.; Amann, J. M.; Cacciato, N.; Rao Arasada, R.; Gerstein, M. B.; Wysocki, V. H.; Oakes, C.; Carbone, D. P.; STK11\/LKB1 loss of function is associated with global DNA hypomethylation and S-adenosyl-methionine depletion in human lung adenocarcinoma. Cancer Res.<\/i> 2021<\/em>. DOI: 10.1158\/0008-5472.CAN-20-3199. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Seffernick, J. T.; Canfield, S. M.; Harvey, S. R.; Wysocki, V. H.; Lindert, S.; Prediction-of-protein-complex-structure-using-surface-induced dissociation-and-cryo-electron-microscopy. Anal. Chem.<\/i> 2021<\/em>, 93, 7596-7605. DOI: 10.1021\/acs.analchem.0c05468. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Harvey, S. R.; VanAernum, Z. L.; Wysocki, V. H.; Surface-induced dissociation of anionic vs cationic native-like protein complexes. J. Am. Chem. Soc.<\/i> 2021<\/em>, 143, 7698-7706. DOI: 10.1021\/jacs.1c00855. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Sahtoe, D. D; Coscia, A.; Mustafaoglu, N.; Miller, L. M.; Olal, D.; Vulovic, I.; Yu, T.-Y.; Goreshnik, I.; Lin, Y.-R.; Clark, L.; Busch, F.; Stewart, L.; Wysocki, V. H.; Ingber, D. E.; Abraham, J.; Baker, D.; Transferring receptor targeting by de novo sheet extension. Proc. Natl. Acad. Sci. USA<\/i> 2021<\/em>, 118, e2021569118. DOI: 10.1073\/pnas.2021569118. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

McCabe, J. W.; Shirzadeh, M.; Walker, T. E.; Lin, C.-W.; Jones, B. J.; Wysocki, V. H.; Barondeau, D. P.; Clemmer, D. E.; Laganowsky, A.; Russell, D. H.; Variable-temperature electrospray ionization for temperature-dependent folding\/refolding reactions of proteins and ligand binding. Anal. Chem.<\/i> 2021<\/em>, 93, 6924-6931. DOI: 10.1021\/acs.analchem.1c00870. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Landeras-Bueno, S.; Wasserman, H.; Oliveira, G.; VanAernum, Z. L.; Busch, F.; Salie, Z. L.; Wysocki, V. H.; Andersen, K.; Ollmann Saphire, E.; Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form. Cell Rep.<\/i> 2021<\/em>, 35, 108986. DOI: 10.1016\/j.celrep.2021.108986. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Caldwell, B. J.; Norris, A.; Zakharova, E.; Smith, C. E.; Wheat, C. T.; Choudhary, D.; Sotomayor, M.; Wysocki, V. H.; Bell, C. E.; Oligomeric complexes formed by Red\u03b2 single strand annealing protein in its different DNA bound states. Nucleic Acids Res.<\/i> 2021<\/em>, 49(6), 3441-3460. DOI: 10.1093\/nar\/gkab125. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Panczyk, E. M.; Snyder, D. T.; Ridgeway, M. E.; Somogyi, A.; Park, M. A.; Wysocki, V. H.; Surface-induced dissociation of protein complexes selected by trapped ion mobility spectrometry. Anal. Chem.<\/i> 2021<\/em>, 93, 5513-5520. DOI: 10.1021\/acs.analchem.0c05373. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Smith, H.; Pinkerton, N.; Heisler, D. B.; Kudryashova, E.; Hall, A. R.; Karch, K. R.; Norris, A.; Wysocki, V.; Sotomayor, M.; Reisler, E.; Vavylonis, D.; Kudryashov, D. S.; Rounding out<\/i> the understanding of ACD toxicity with the discovery of cyclic forms of actin oligomers. Int. J. Mol. Sci.<\/i> 2021<\/em>, 22, 718. DOI: 10.3390\/ijms22020718. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Vorobieva, A. A.; White, P.; Liang, B.; Horne, J. E.; Bera, A. K.; Chow, C. M.; Gerben, S.; Marx, S.; Kang, A.; Stiving, A. Q.; Harvey, S. R.; Marx, D. C.; Khan, G. N.; Fleming, K. G.; Wysocki, V. H.; Brockwell, D. J.; Tamm, L. K.; Radford, S. E.; Baker, D. De Novo Design of Transmembrane \u03b2-Barrels, Science, 2021, 371 (6531), eabc8182. DOI: 10.1126\/science.abc8182. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Snyder, D. T.; Harvey, S. R.; Busch, F.; Wysocki, V. H. Chapter 11: Surface-Induced Dissociation in Biomolecular Mass Spectrometry. In Advanced Fragmentation Methods. Biomolecular Mass Spectrometry; 2020; pp 281\u2013336. DOI: 10.1039\/9781839161056-00281.<\/p>\n

Snyder, D. T.; Lin, Y.-F.; Somogyi, A.; Wysocki, V. H.; Tandem surface-induced dissociation of protein complexes on an ultrahigh resolution platform. International Journal of Mass Spectrometry. 2021<\/strong><\/em>, 461, 116503. DOI: 10.1016\/j.ijms.2020.116503. [Request reprint \u00a9 (pdf)] <\/a>[Cover article]<\/a><\/p>\n

Harvey, S.R.; VanAernum, Z.L.; Kostelic, M.M.; Marty, M.T. and Wysocki, V.H.; Probing the structure of nanodiscs using surface-induced dissociation mass spectrometry. Chemical Communications.\u00a02020,<\/strong><\/i> 56<\/i>(100), 15651-15654. DOI: 10.1039\/D0CC05531J. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Agana, B.A.; Wysocki, V.H. and Schoenberg, D.R.; Cytoplasmic mRNA recapping has limited impact on proteome complexity. Open Biology.\u00a02020,<\/strong><\/i> 10<\/i>(11), 200313. DOI: 0.1098\/rsob.200313. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Stiving, A.Q.; Harvey, S.R.; Jones, B.J.; Bellina, B.; Brown, J.M.; Barran, P.E. and Wysocki, V.H.; Coupling 193 nm Ultraviolet Photodissociation and Ion Mobility for Sequence Characterization of Conformationally-Selected Peptides. J. Am. Soc. Mass Spectrom.\u00a02020,<\/strong><\/em> 31<\/i>(11),2313-2320. DOI: 10.1021\/jasms.0c00259.[Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Sarni, S.; Biswas, B.; Liu, S.; Olson, E. D.; Kitzrow, J.; Rein, A.; Wysocki, V.; Musier-Forsyth, K.;\u00a0 HIV-1 Gag protein with or without p6 specifically dimerizes on the packaging signal in viral RNA. J. Biol. Chem.<\/em> 2020<\/strong>, 295(42),14391-14401. DOI: 10.1074\/jbc.RA120.014835. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Snyder, D. T.; Panczyk, E. M.; Somogyi, A.; Kaplan, D. A.; Wysocki, V.; Simple and Minimally Invasive SID Devices for Native Mass Spectrometry. Analytical Chemistry<\/em> 2020<\/strong>,92, 16, 11195\u201311203. DOI: 10.1021\/acs.analchem.0c01657. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Holmquist, M.; Ihms, E. C., Gollnick, P.; Wysocki, V. H.; and Foster, M. P.; Population distributions from native mass spectrometry titrations reveal nearest-neighbor cooperativity in the ring-shaped oligomeric protein TRAP. Biochemistry<\/i>. 2020<\/strong>, 59, 27, 2518\u2013252. DOI: 10.1021\/acs.biochem.0c00352. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Bansal, P.; Yatsyna, V.; AbiKhodr, A. H.; Warnke, S.; Ben Faleh, A.; Yalovenko, N.; Wysocki, V. H. and Rizzo, T. R.; Using SLIM-based IMS-IMS together with cryogenic infrared spectroscopy for glycan analysis. Analytical Chemistry<\/i>. 2020<\/strong>,\u00a092, 9079\u22129085. DOI: 10.1021\/acs.analchem.0c01265. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Vimer, S.; Ben-Nissan, G.; Morgenstern, D.; Kumar-Deshmukh, F.; Polkinghorn, C.; Quintyn, R. S.; Vasil\u2019ev, Y. V.; Beckman, J. S.; Elad, N.; Wysocki, V. H.; and Sharon, M.; Comparative structural analysis of 20S proteasome ortholog protein complexes by native mass spectrometry. ACS Central Science<\/i>. 2020<\/strong>, 6<\/span>(4):<\/span> 573-588.<\/span> DOI: 10.1021\/acscentsci.0c00080. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Chen, Z.; Kibler, R.;\u00a0 Hunt, A.; Busch, F.; Pearl, J.; Jia, M.; VanAernum, Z. L.; Wicky, B. I. M.; Dods, G.; Liao, H.; Wilken, M. S.; Ciarlo, C.; Green, S.; El-Samad, H.; Stamatoyannopoulos, J.; Wysocki, V. H.; Jewett, M. C.; Boyken, S. E.; and Baker, D.; <\/span> De novo design of protein logic gates. Science. <\/em>2020<\/strong>, 368 (6486): 78-84. DOI: 10.1126\/science.aay2790. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Jia, M.; Sen, S.; Wachnowsky, C.; Fidai, I.; Cowan, J.A. and Wysocki, V. H.; Characterization of [2Fe\u20102S]\u2010Cluster\u2010Bridged Protein Complexes and Reaction Intermediates by use of Robust Native Mass Spectrometric Methods. Angewandte Chemie International Edition<\/i>. 2020<\/strong>,\u00a059 (17), 6724-6728. DOI: 10.1002\/anie.201915615.[Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Stiving, A. Q.; Jones, B. J.; Ujma, J.; Giles, K. and Wysocki, V. H.; Collision Cross Sections of Charge-Reduced Proteins and Protein Complexes: a Database for CCS Calibration. Analytical Chemistry<\/i>. 2020<\/strong>, 92, 4475-4483. DOI: 10.1021\/acs.analchem.9b05519. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Norris, A.; Busch, F.; Schupfner, M.; Sterner, R. and Wysocki, V. H.; Quaternary Structure of the Tryptophan Synthase \u03b1\u2011Subunit Homolog BX1 from Zea mays. J. Am. Soc. Mass Spectrom. <\/em>2020<\/strong>, 31(2):227-233.\u00a0DOI: 10.1021\/jasms.9b00068. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Panczyk, E.M.; Gilbert, J. D.; Jagdale, G. S.; Stiving, A. Q.; Baker, L. A. and Wysocki, V. H.; Ion Mobility and Surface Collisions: Submicrometer Capillaries Can Produce Native-like Protein Complexes. Anal Chem.<\/em>\u00a02020<\/strong>, 92(<\/span>3):<\/span>2460-2467.<\/span> DOI: 10.1021\/acs.analchem.9b03666. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

VanAernum, Z.; Busch, F.; Jones, B. J.; Jia, M.; Chen, Z.; Boyken, S. E.; Sahasrabuddhe, A.; Baker, D.; Wysocki, V. H. Rapid Online Buffer Exchange: A Method for Screening of Proteins, Protein Complexes, and Cell Lysates by Native Mass Spectrometry. Nat Protoc.<\/i>\u00a02020,<\/strong>\u00a015, 1132-1157. DOI: 10.1038\/s41596-019-0281-0. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Stiving, A.Q.; Gilbert, J.D.; Jones, B. J.; Wysocki, V. H.; A Tilted Surface and Ion Carpet Array for SID. J. Am. Soc. Mass Spectrom. <\/em>2020, <\/strong>31(2):458-462 DOI: 10.1021\/jasms.9b00009. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Kang, M.; Doddapaneni, K.; Sarni, S.; Heppner, Z.; Wysocki, V.; and Wu, Z.; Solution Structure of the Nucleotide hydrolase BlsM: Implication of its Substrate Specificity. Protein Science<\/i>. 2019<\/strong>,29 (8), 1760-1763. DOI: 10.1002\/pro.3812. [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Cardona, A.; O\u2019Brien, A.; Bernier, M.C.; Somogyi, A.; Wysocki, V.H.; Smark S.; He, X.; Ambrosia, G.; Hsueh, W.A.; Raman, S.V. Trimethylamine N-oxide and incident atherosclerotic events in high-risk individuals with diabetes: an ACCORD trial post hoc analysis. BMJ Open Diab Res Care. 2019<\/strong>; 7 (1): e000718. DOI: 10.1136\/bmjdrc-2019-000718 [Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Purde, V.; Busch, F.; Kudryashova, E.; Wysocki, V. H. and Kudryashov, D. S.; Oligomerization Affects the Ability of Human Cyclase-Associated Proteins 1 and 2 to Promote Actin Severing by Cofilins. Int J Mol Sci. <\/em>2019<\/strong>, 20(22):5647. DOI: 10.3390\/ijms20225647 <\/em>[Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Kneuttinger, A. C.; Zwisele, S.; Straub, K.; Bruckmann, A.; Busch, F.; Kinateder, T.; Gaim, B.; Wysocki, V. H.; Merkl, R.; Sterner, R.; Light-Regulation of Tryptophan Synthase by Combining Protein Design and Enzymology. Int J Mol Sci.<\/em>\u00a02019, <\/strong>20(20): 5106. DOI: 10.3390\/ijms20205106 [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Snyder, D.T.; Panczyk, E.; Stiving, A.Q.; Gilbert, J.D.; Somogyi, A.; Kaplan, D.; Design and Performance of a Second-Generation Surface-Induced Dissociation Cell for Fourier Transform Ion Cyclotron Resonance Mass Spectrometry of Native Protein Complexes.\u00a0Anal. Chem.<\/em>\u00a02019,<\/strong> 91(21):14049-14057. DOI: 10.1021\/acs.analchem.9b03746 [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Kneuttinger, A.C.; Straub, K.; Bittner, P.; Simeth, N.A.; Bruckmann, A.; Busch, F.; Rajendran, C.; Hupfeld, E.; Wysocki, V.H.; Horinek, D.; K\u00f6nig, B., Light Regulation of Enzyme Allostery through Photo-responsive Unnatural Amino Acids. Cell Chem Biol<\/em>. 2019<\/strong>, 26(11):1501-1514. DOI: 10.1016\/j.chembiol.2019.08.006 [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Sengupta, A.; Wu, J.; Seffernick, J.T.; Sabag-Daigle, A.; Thomsen, N.; Chen, T.H.; Di Capua, A.; Bell, C.E.; Ahmer, B.M.; Lindert, S.;\u00a0 Wysocki, V.H.; Gopalan V., Integrated use of biochemical, native mass spectrometry, computational and genome-editing methods to elucidate the mechanism of a Salmonella deglycase. Journal of molecular biology. J Mol Biol<\/em>. 2019<\/strong>, 431(22):4497-4513. DOI: 10.1016\/j.jmb.2019.08.017\u00a0 [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Seffernick, J. T.; Harvey, S. R.; Wysocki, V. H.; Lindert, S., Predicting Protein Complex Structure from Surface-Induced Dissociation Mass Spectrometry Data. ACS Cent Sci<\/em>. 2019<\/strong>, 5(8):1330-1341. DOI: 10.1021\/acscentsci.8b00912.[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Smith, Z.M; Wang, X.; Scheerer, J. R.; Martens, J.; Berden, G.; Oomens, J.; Steinmetz, V.; Somogyi, A.; Wysocki, V. H.; Poutsma, J. C., Spectroscopic Evidence for Lactam Formation in Terminal Ornithine b2+\u00a0<\/sup>and b3+\u00a0Fragment Ions. J. Am. Soc. Mass Spectrom<\/em>. 2019<\/strong>, 30(9):1565-1577. DOI: 10.1007\/s13361-019-02244-0. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Boyken, S. E.; Benhaim, M. A.; Busch, F.; Jia, M.; Bick, M. J.; Choi, H.; Klima, J. C.; Chen, Z.; Walkey, C.; Mileant, A.; Sahasrabuddhe, A.; Wei, K. Y.; Hodge, E. A.; Byron, S.; Quijano-Rubio, A.; Sankaran, B.; King, N. P.; Lippincott-Schwartz, J.; Wysocki, V. H.; Lee, K.K.; Baker D., De novo design of tunable, pH-driven conformational changes. Science.<\/em> 2019<\/strong>, 364(6441):658-664. DOI: 10.1126\/science.aav7897.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Schupfner, M.; Busch F.; Wysocki, V.; Sterner, R., Generation of a stand-alone tryptophan synthase \u03b1-subunit by mimicking an evolutionary blueprint. Chembiochem.<\/em> 2019<\/strong>, 20(21):2747-2751. DOI: 10.1002\/cbic.201900323. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Harvey, S. R.; Seffernick, J. T.; Quintyn, R. S.; Song, Y.; Ju, Y.; Yan, J.; Sahasrabuddhe, A. N.; Norris, A.; Zhou, M.; Behrman, E. J.; Lindert, S.; Wysocki, V. H., Relative interfacial cleavage energetics of protein complexes revealed by surface collisions. PNAS.<\/em>\u00a02019,<\/strong> 116(17):8143-8148. DOI: 10.1073\/pnas.1817632116.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

VanAernum, Z. L.; Gilbert, J. D.; Belov, M. E.; Makarov, A. A.; Horning, S. R.; Wysocki, V. H., Surface-Induced Dissociation of Noncovalent Protein Complexes in an Extended Mass Range Orbitrap Mass Spectrometer.\u00a0Anal Chem<\/em>. 2019<\/strong>, 91(5):3611-3618. DOI: 10.1021\/acs.analchem.8b05605. .\u00a0 [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Chen, Z.; Boyken, S. E.; Jia, M.; Busch, F.; Flores-Solis, D.; Bick, M. J.; Lu, P.; VanAernum, Z. L.; Sahasrabuddhe, A.; Langan, R. A.; Bermeo, S.; Brunette, T. J.; Mulligan, V. K.; Carter, L. P.; DiMaio, F.; Sgourakis, N. G.; Wysocki, V. H.; Baker, D., Programmable design of orthogonal protein heterodimers. Nature<\/em>. 2019, <\/strong>565(7737):106-111. DOI: 10.1038\/s41586-018-0802-y.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Chen, L.; Tanimoto, A.; So, B. R.; Bakhtina, M.; Magliery, T. J.; Wysocki, V. H.; Musier-Forsyth, K., Stoichiometry of triple-sieve tRNA editing complex ensures fidelity of aminoacyl-tRNA formation. Nucleic Acids Res<\/em>. 2019<\/strong>,47(2):929-940. DOI: 10.1093\/nar\/gky1153.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Stiving, A. Q.; VanAernum Z.; Busch, F.; Harvey S. R.; Sarni, S.; Wysocki, V. H., Surface-Induced Dissociation: An Effective Method for Characterization of Protein Quaternary Structure. Anal Chem<\/em>. 2019<\/strong>, 91(1):190-209. DOI: 10.1021\/acs.analchem.8b05071. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Mabin, J. W.; Woodward, L. A.; Patton, R. D.; Yi, Z.; Jia, M.; Wysocki, V. H.; Bundschuh, R.; Singh, G., The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity. Cell Rep<\/em>. 2018<\/strong>, 25(9):2431-2446.e7. DOI: 10.1016\/j.celrep.2018.11.046. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Busch, F.; VanAernum, Z. L.; Ju, Y.; Yan, J.; Gilbert, J. D.; Quintyn, R. S.; Bern, M.; Wysocki, V. H., Localization of protein complex bound ligands by surface-induced dissociation high-resolution mass spectrometry, Anal Chem<\/em>. 2018<\/strong>, 90(21):12796-12801. DOI: 10.1021\/acs.analchem.8b03263. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Trotman, J. B.; Agana, B. A.; Giltmier, A. J.; Wysocki, V. H.; Schoenberg, D. R., RNA-binding proteins and heat-shock protein 90 are constituents of the cytoplasmic capping enzyme interactome, JBC.<\/em> 2018,<\/strong> 293(43):16596-16607. DOI:\u00a010.1074\/jbc.RA118.004973.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Sharpnack, M. F.; Ranbaduge, N.; Srivastava, A.; Cerciello, F.; Codreanu, S. G.; Liebler, D. C.; Mascaux, C.; Miles, W. O.; Morris, R.; McDermott, J. E.; Sharpnack, J. L.; Amann, J.; Maher, C. A.; Machiraju, R.; Wysocki, V. H.; Govindan, R.; Mallick, P.; Coombes, K. R.; Huang, K.; Carbone, D. P., Proteogenomic Analysis of Surgically Resected Lung Adenocarcinoma,\u00a0J Thorac Oncol<\/em>. 2018<\/strong>, 13(10):1519-1529. DOI: 10.1016\/j.jtho.2018.06.025.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Gadkari, V. V.; Harvey, S. R.; Raper, A. T.; Chu, W. T.; Wang, J.; Wysocki, V. H.; Suo, Z., Investigation of sliding DNA clamp by single-molecule fluorescence, mass spectrometry and structure-based modeling, Nucleic Acids Res.<\/em> 2018<\/strong>, 46(6):3103-3118. DOI: 10.1093\/nar\/gky125. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Wu, J.; Sabag-Daigle, A.; Borton, M. A.; Kop, L. F. M.; Szkoda, B. E.; Deatherage Kaiser, B. L.; Lindemann, S. R.; Renslow, R. S.; Wei, S.; Nicora, C. D.; Weitz, K. K.; Kim, Y. M.; Adkins, J. N.; Metz, T. O.; Boyaka, P.; Gopalan, V.; Wrighton, K. C.; Wysocki, V. H.; Ahmer, B. M. M.,\u00a0Salmonella-Mediated Inflammation Eliminates Competitors for Fructose-Asparagine in the Gut, Infect Immun.<\/em> 2018<\/strong>, 86(5). pii: e00945-17. DOI: 10.1128\/IAI.00945-17. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Aebersold, R.; Agar, J. N.; Amster, I. J. A.; Baker, M. S. A.; Bertozzi, C. R.; Boja, E. S.; Costello, C. E.; Cravatt, B. F. A.; Fenselau, C.; Garcia, B. A.; Ge, Y.; Gunawardena, J.; Hendrickson, R. C.; Hergenrother, P. J.; Huber, C. G. A.; Ivanov, A. R.; Jensen, O. N.; Jewett, M. C.; Kelleher, N. L. A.; Kiessling, L. L. A.; Krogan, N. J.; Larsen, M. R.; Loo, J. A. A.; Ogorzalek Loo, R. R.; Lundberg, E.; MacCoss, M. J.; Mallick, P.; Mootha, V. K.; Mrksich, M.; Muir, T. W.; Patrie, S. M.; Pesavento, J. J. A.; Pitteri, S. J. A. X.; Rodriguez, H.; Saghatelian, A.; Sandoval, W.; Schluter, H. A.; Sechi, S.; Slavoff, S. A.; Smith, L. M.; Snyder, M. P.; Thomas, P. M. A.; Uhlen, M.; Van Eyk, J. E.; Vidal, M.; Walt, D. R.; White, F. M.; Williams, E. R.; Wohlschlager, T.; Wysocki, V. H.; Yates, N. A.; Young, N. L. A.; Zhang, B. A., How Many Human Proteoforms Are There?\u00a0 Nat Chem Biol.<\/em> 2018<\/strong>, 14(3):206-214. DOI: 10.1038\/nchembio.2576.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/span><\/p>\n

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Zhou, M.; Yan, J.; Romano, C. A.; Tebo, B. M.; Wysocki, V. H.;\u00a0Pa\u0161a-Toli\u0107, L., Surface Induced Dissociation Coupled with High Resolution Mass Spectrometry Unveils Heterogeneity of a 211 kDa Multicopper Oxidase Protein Complex, J Am Soc Mass Spectrom.<\/em> 2018<\/strong>, 29(4):723-733. DOI: 10.1007\/s13361-017-1882-x.[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/span><\/p>\n

Sahasrabuddhe, A.; Hsia, Y.; Busch, F.; Sheffler, W.; King, N. P.; Baker, D.; Wysocki, V. H., Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS, PNAS. <\/em>2018, <\/strong>115(6):1268-1273.\u00a0<\/strong>DOI:\u00a0<\/strong>10.1073\/pnas.1713646115.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Wu, J.; Sabag-Daigle, A.; Metz, T. O.; Deatherage Kaiser, B. L.; Gopalan, V.; Behrman, E. J.; Wysocki, V. H.; Ahmer, B. M. M., Measurement of Fructose-Asparagine Concentrations in Human and Animal Foods, J. Agric. Food Chem.<\/em> 2018<\/strong>, 66(1):212-217. DOI: 10.1021\/acs.jafc.7b04237.[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Sabag-Daigle, A.; Wu, J.; Borton, M. A.; Sengupta, A.; Gopalan, V.; Wrighton, K. C.; Wysocki, V. H.; Ahmer, B. M. M., Identification of bacterial species that can utilize fructose-asparagine,\u00a0Appl Environ Microbiol.<\/em><\/span>\u00a02017<\/strong>, 84(5). pii: e01957-17. DOI: 10.1128\/AEM.01957-17.[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Park, M.;\u00a0<\/span>Phan, H.;<\/span>\u00a0Busch, F.;<\/span>\u00a0Hinckley, S. H.;\u00a0<\/span>Brackbill, J. A.;<\/span>\u00a0Wysocki, V. H.;<\/span>\u00a0Nakanishi, K.,\u00a0<\/span>Human Argonaute3 has slicer activity,\u00a0Nucleic Acids Research<\/em>\u00a02017<\/strong>, 45(20):11867-11877. DOI: 10.1093\/nar\/gkx916 [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Bungard, D.; Copple, J. S.; Yan, J.; Chhun, J. J.; Kumirov, V. K.; Foy, S. G.; Masel, J.; Wysocki, V. H.; Cordes, M. H. J., Foldability of a Natural De Novo\u00a0<\/em>Evolved Protein,\u00a0Structure<\/em>\u00a02017<\/strong>, 25(11):1687-1696.e4. DOI: 10.1016\/j.str.2017.09.006. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Romano, C. A.; Zhou, M.; Song, Y.; Wysocki, V. H.; Dohnalkova, A. C.; Kovarik, L.; Pa\u0161a-Toli\u0107, L.; Tebo, B. M., Biogenic manganese oxide nanoparticle formation by a multimeric multicopper oxidase Mnx, Nature Communications<\/i>\u00a0,\u00a0<\/em>2017<\/strong>,\u00a08(1):746. DOI: 10.1038\/s41467-017-00896-8,<\/em>\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Plach, M. G.; Semmelmann, F.; Busch, F.; Busch, M.; Heizinger, L.; Wysock, V. H.; Merkl, R.; Sterner, R., Evolutionary diversification of protein-protein interactions by interface add-ons,\u00a0Proc Nat Acad Sci,\u00a0<\/em>2017<\/strong>, 114(40):E8333-E8342. DOI: 10.1073\/pnas.1707335114.\u00a0 [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

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Lai, L. B.; Tanimoto, A.; Lai, S. M.; Chen, W.; Marathe, I. A.; Westhof, E.; Wysocki, V. H.; Gopalan, V., A novel double kink-turn module in euryarchaeal RNase P RNAs,\u00a0Nucleic Acids Research<\/em>,\u00a02017<\/strong>, 45(12):7432-7440.\u00a0 DOI: 10.1093\/nar\/gkx388 [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

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Borton, M. A.; Sabag-Daigle, A.; Wu, J.; Solden, L. M.; O\u2019Banion, B. S.; Daly, R. A.;Wolfe, R. A.; Gonzalez, J. F.;Wysocki, V. H.; Ahmer, B. M. M.; Wrighton, K. C., Chemical and pathogen-induced inflammation disrupt the murine intestinal microbiome, Microbiome<\/em>.,\u00a02017<\/strong>, 5(1):47. DOI: 10.1186\/s40168-017-0264-8.\u00a0<\/em>[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Poutsma, J. C.; Martens, J.; Oomens, J.; Maitre, P.; Steinmetz, V.; Bernier, M. C.; Jia, M.; Wysocki, V. H., Infrared Multiple-Photon Dissociation Action Spectroscopy of the b2+ Ion from PPG: Evidence of Third Residue Affecting b2+ Fragment Structure,\u00a0Journal of The American Society for Mass Spectrometry,\u00a0<\/em>2017, <\/strong>28(7):1482-1488. DOI: 10.1007\/s13361-017-1659-2.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

Harvey, S. R.; Liu, Y.; Liu, W.; Wysocki, V. H., Laganowsky<\/span>, A.; Surface induced dissociation as a tool to study membrane protein complexes, ChemComm., <\/em>2017<\/strong>, 53(21):3106-3109. DOI: 10.1039\/C6CC09606A.\u00a0<\/em>[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n<\/div>\n

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Garfoot, A. L.; Dearing, K. L.; VanSchoiack, A. D.; Wysocki, V. H.; Rappleye, C. A., Eng1 and Exg8 Are the Major -Glucanases Secreted by the Fungal Pathogen Histoplasma capsulatum, J.Biol.Chem.<\/em>,\u00a02017<\/strong>,\u00a0292(12):4801-4810. DOI:10.1074\/jbc.M116.762104<\/span>\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Catcott, K. C.; Yan, J.; Qu, W.; Wysocki, V. H.; Zhou, Z. S., Identifying Enzyme-Substrate Pairs in the Cellular Milieu with Native Mass Spectrometry, ChemBioChem.<\/em>, 2017<\/strong>, 18(7):613-617.DOI:10.1002\/cbic.201600634.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a>\u00a0[Cover article]<\/a><\/p>\n

Yan, J.;\u00a0Zhou, M.;<\/span>\u00a0Gilbert, J. D.\u00a0;<\/span>\u00a0Wolff, J. J.;<\/span>\u00a0Somogyi, A.;<\/span>\u00a0Pedder, R. E.;\u00a0\u00a0<\/span>Quintyn, R. S.; Morrison, L. J.;\u00a0Easterling, M. L.; <\/span>Pa\u0161a-Toli\u0107<\/span>, L.; Wysocki , V. H,\u00a0<\/span>Surface-induced dissociation (SID) of protein complexes in a hybrid Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer, Anal. Chem., <\/em>2017<\/strong>, 89(1):895-901. <\/em>DOI: 10.1021\/acs.analchem.6b03986. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Chen, T.; Tanimoto, A.; Shkriabai, N.; Kvaratskhelia, M.; Wysocki, V. H.; Gopalan, V., Use of chemical modification and mass spectrometry to identify substrate-contacting sites in proteinaceous RNase P, a tRNA processing enzyme, Nucleic Acids Research.<\/em>\u00a02016, <\/strong>44(11):5344-5355. DOI<\/span>: 10.1093\/nar\/gkw39.[Request reprint \u00a9 (pdf)]<\/a><\/span><\/span><\/p>\n

Sabag-Daigle, A.; Blunk, H. M.; Sengupta,\u00a0A.; Wu, J.; Bogard, A.\u00a0J.;\u00a0Ali, M.\u00a0M.; Stahl, C.; Wysocki, V. H.; Gopalan,V.; Behrman, E. J.; Ahmer,\u00a0B.\u00a0M. M,\u00a0<\/span>A metabolic intermediate of the fructose-asparagine utilization pathway inhibits growth of a Salmonella fraB mutant,\u00a0Scientific Reports<\/i>,\u00a0<\/em>2016, <\/strong>6:28117. DOI<\/span>:\u00a0<\/span>10.1038\/srep28117.\u00a0<\/span><\/span>[Request reprint \u00a9 (pdf)]<\/a><\/span><\/span><\/p>\n

Nelp, M. T.; Song, Y.; Wysocki, V. H.;\u00a0Bandarian, V.,\u00a0A Protein-Derived Oxygen is the Source of the Amide\u00a0Oxygen of Nitrile Hydratases, <\/span>Journal of Biological Chemistry<\/em>,\u00a02016<\/strong>,\u00a0<\/strong>291: 7822-7829.<\/em>[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/span><\/p>\n

Baksi, A.; Harvey, S. R.; Natarajan, G; Wysocki, V. H.; Pradeep, T, Possible isomers in ligand protected Ag11 cluster ions identified by ion mobility mass spectrometry and fragmented by surface induced dissociation,\u00a0Chemical Communications,<\/em> 2016<\/strong>, 52: 3805-3808.<\/em>[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/span><\/p>\n

Harvey, S. R.; Yan. J., Brown, J. M.; Hoyes, E.; Wysocki V. H.,\u00a0Extended gas-phase trapping followed by surface-induced dissociation of non-covalent protein complexes,\u00a0Analytical Chemistry,\u00a02016<\/strong>, 88: 1218-1221<\/em>.[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Bernier, M. C.;\u00a0Chamot-Rooke, J.; Wysocki, V.H,\u00a0R vs. S Fluoroproline ring substitution: trans\/cis effects on the formation of b2 ions in gas-phase peptide fragmentation, Physical Chemistry Chemical Physics<\/em>, 2016<\/strong>, 18: 2202-2209. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Xu, B.; Ju, Y.; Soukup, R. J.;\u00a0Ramsey, D. M.; Fishel, R.; Wysocki, V. H.; Wozniak, D .J., The Pseudomonas aeruginosa AmrZ C-terminal domain mediates tetramerization and is required for its activator and repressor functions,\u00a0Environmental Microbiology Reports<\/em>,\u00a02016<\/strong>,<\/em>\u00a0DOI: <\/span>10.1111\/1758-2229.12354<\/span> [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Song, Y.; Nelp, M. T.; Bandarian, V.; Wysocki, V. H.,\u00a0Refining the Structural Model of a Hetero-hexameric Protein Complex: Surface Induced Dissociation and Ion Mobility Provide Key Connectivity and Topology Information, ACS Central Science<\/em>, 2015<\/strong>, 1, 477-487.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a> [Cover article]<\/a><\/p>\n

Morrison, L. J.; Wysocki, V. H.,\u00a0Low energy CID and action IRMPD provide insights into a minor subpopulation of the gas-phase conformers of triply charged bradykinin, International Journal of Mass Spectrometry,\u00a02015<\/strong>, 391, 2-10.\u00a0<\/i>[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Quintyn, R. S.; Zhou, Z.; Yan, J.; Wysocki, V. H., \u00a0Surface-induced dissociation mass spectra distinguish different structural forms of gas-phase multimeric protein complexes,\u00a0Analytical Chemistry,\u00a02015<\/strong>, 87, 11879-11886.\u00a0<\/em> [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Jacobs, A. D.; Chang, F.-M. J.; Morrison, L.; Dilger, J. M.; Wysocki, V. H.; Clemmer, D. E.; Giedroc, D. P., Resolution of Stepwise Cooperativities of Copper Binding by the Homotetrameric Copper-Sensitive Operon Repressor (CsoR): Impact on Structure and Stability. Angewandte Chemie International Edition <\/em>2015<\/strong>, 54, 12795-12799.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Quintyn, R. S.; Harvey, S. R.; Wysocki, V. H., Illustration of SID-IM-SID (surface-induced dissociation-ion mobility-SID) mass spectrometry: homo and hetero model protein complexes. Analyst<\/em>, 2015<\/strong>, 140, 7012.\u00a0\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Bernier, M. C.; Wysocki, V. H.; Dagan, S., Laser desorption ionization of small molecules assisted by tungsten oxide and rhenium oxide particles. Journal of Mass Spectrometry <\/em>2015<\/strong>; 50<\/em> (7), 891-898.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Song, Y.; Laskay, \u00dc.; Vilcins, I.-M.; Barbour, A.; Wysocki, V., Top-Down-Assisted Bottom-Up Method for Homologous Protein Sequencing: Hemoglobin from 33 Bird Species. Journal of The American Society for Mass Spectrometry <\/em>2015<\/strong>; 26<\/em> (11), 1875-1884.[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Quintyn, Royston\u00a0S.; Yan, J.; Wysocki, Vicki\u00a0H., Surface-Induced Dissociation of Homotetramers with D2 Symmetry Yields their Assembly Pathways and Characterizes the Effect of Ligand Binding. Chemistry & Biology <\/em>2015<\/strong>; 22<\/em> (5), 583-592.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Shah, S.; Sanchez, J.; Stewart, A.; Piperakis, M. M.; Cosstick, R.; Nichols, C.; Park, C. K.; Ma, X.; Wysocki, V.; Bitinaite, J.; Horton, N. C., Probing the Run-On Oligomer of Activated SgrAI Bound to DNA. PLoS ONE <\/em>2015<\/strong>; 10<\/em> (4), e0124783.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Ma, X.; Loo, J. A.; Wysocki, V. H., Surface induced dissociation yields substructure of Methanosarcina thermophila 20S proteasome complexes. International Journal of Mass Spectrometry <\/em>2015<\/strong>; 377<\/em> (0), 201-204.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Liang, B.; Ju, Y.; Joubert, J. R.; Kaleta, E. J.; Lopez, R.; Jones, I. W.; Hall, H. K., Jr.; Ratnayaka, S. N.; Wysocki, V. H.; Saavedra, S. S., Label-free detection and identification of protein ligands captured by receptors in a polymerized planar lipid bilayer using MALDI-TOF MS. Anal. Bioanal. Chem. <\/em>2015<\/strong>, Ahead of Print.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

White, M. R.; Khan, M. M.; Deredge, D.; Ross, C. R.; Quintyn, R.; Zucconi, B. E.; Wysocki, V. H.; Wintrode, P. L.; Wilson, G. M.; Garcin, E. D., A dimer interface mutation in glyceraldehyde-3-phosphate dehydrogenase regulates its binding to AU-rich RNA. J. Biol. Chem. <\/em>2015<\/strong>;\u00a0290<\/em> (3), 1770-1785.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Harvey, S. R.; Wysocki, V. H., Mass spectrometry Bound in flight. Nat. Chem. <\/em>2015<\/strong>;\u00a07<\/em> (3), 189-190.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Pan, X.; Yan, J.; Patel, A.; Wysocki, V. H.; Bell, C. E., Mutant Poisoning Demonstrates a Nonsequential Mechanism for Digestion of Double-Stranded DNA by \u03bb Exonuclease Trimers. Biochemistry <\/em>2015<\/strong>;\u00a054<\/em> (3), 942-951;\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Raulfs, M. D. M.; Breci, L.; Bernier, M.; Hamdy, O. M.; Janiga, A.; Wysocki, V.; Poutsma, J. C., Investigations of the mechanism of the “Proline Effect” in Tandem Mass spectrometry experiments: The “Pipecolic Acid Effect”. J. Am. Soc. Mass Spectrom. <\/em>2014,<\/strong> 25<\/em> (10), 1705-1715.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Morrison, L. J. and Wysocki, V. H.; Gas-Phase Helical Peptides Mimic Solution-Phase Behavior. J. Am. Chem. Soc.\u00a02014<\/strong>;\u00a0136, 14173-14183.[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Kudryashova, E.; Quintyn, R.; Seveau, S.; Lu, W.; Wysocki, Vicki\u00a0H.; Kudryashov, Dmitri\u00a0S. Human Defensins Facilitate Local Unfolding of Thermodynamically Unstable Regions of Bacterial Protein Toxins. Immunity<\/em>, 2014<\/strong>;\u00a041(5), 709-721.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Harshman, S.W.; Hoover, M.E.; Huang, C.S.; Branson, O.E.; Chaney, S.B.; Cheney, C.M.; Rosol, T.J.; Shapiro, C.L.; Wysocki, V.H,; Huebner, K.; Freitas, M.A. Histone H1 Phosphorylation in Breast Cancer. J. Proteome Res.<\/em> 2014<\/strong>;13, 2453-2467. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Ma, X.; Lai, L.B.; Lai, S.M.; Tanimoto, A.; Foster, M.P.; Wysocki, V.H.; Gopalan, V. Uncovering the Stoichiometry of Pyrococcus furiosus RNase P, a Multi-subunit Catalytic Ribonucleoprotein Complex, by Surface-Induced Dissociation and Ion Mobility-Mass Spectrometry. Angew. Chem. Int. Ed. Engl.<\/em> 2014<\/strong>;53(43),\u00a011483\u201311487.[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Seeger, F.; Quintyn, R.; Tanimoto, A.; Williams, G.J.; Tainer, J.A.; Wysocki, V.H.; Garcin, E.D. Interfacial Residues Promote an Optimal Alignment of the Catalytic Center in Human Soluble Guanylate Cyclase: Heterodimerization Is Required but Not Sufficient for Activity. Biochem.<\/em> 2014<\/strong>;53(13), 2153-2165. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Morrison, L.; Chamot-Rooke, J.; Wysocki, V.H., IR Action Spectroscopy Shows Competitive Oxazolone and Diketopiperazine Formation in Peptides Depends on Peptide Length and Identity of Terminal Residue in the Departing Fragment, Analyst<\/em>, 2014<\/strong>;139(19), 2137-2143. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Ihms, E.C.; Zhou, M.; Zhang, Y.; Kleckner, I.R.; McElroy, C.A.; Wysocki, V.H.; Gollnick, P.; Foster, M.P., Gene regulation by substoichiometric heterocomplex formation of undecameric TRAP and trimeric anti-TRAP, Proc Nat Acad Sci<\/em> 2014<\/strong> [Request reprint \u00a9<\/sup> (pdf)]<\/a> [supplementary material \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Ma, X.; Zhou, M.; Wysocki, V.H., Surface induced dissociation yields quaternary substructure of refractory noncovalent phosphorylase B and glutamate dehydrogenase complexes. J. Am. Soc. Mass Spectrom<\/em>. 2014<\/strong>;25:368-379. [Request reprint \u00a9<\/sup> (pdf)]<\/a> [supplementary material \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Zhou, M.; Wysocki, V.H., Surface induced dissociation: Dissecting noncovalent protein complexes in the gas phase. Acc. Chem. Res.<\/em> 2014<\/strong>;\u00a047(4), 1010-1018 [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Zhang, Y.; Ju, Y.; Huang, C.; Wysocki, V.H., Paper spray ionization of noncovalent protein complexes. Anal Chem.<\/em> 2014<\/strong>;86(3):1342-6. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Gucinski, A.C.; Chamot-Rooke, J.; Steinmetz, V.; Somogyi, A.; Wysocki, V.H., Influence of N-terminal residue composition on the structure of proline-containing b2+ ions. J Phys Chem A.<\/em> 2013<\/strong>;117(6):1291-8. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Zhou, M.; Jones, C.M.; Wysocki, V.H., Dissecting the Large Noncovalent Protein Complex GroEL with Surface-Induced Dissociation and Ion Mobility-Mass Spectrometry. Anal Chem.<\/em> 2013<\/strong>;85(17):8262-7. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Laskay, U.A.; Breci, L.; Vilcins, I.-M.E.; Dietrich, G.; Barbour, A.G.; Piesman, J.; Wysocki, V.H.,\u00a0Survival of Host Blood Proteins in Ixodes scapularis (Acari: Ixodidae) Ticks: A Time Course Study. Journal of Medical Entomology<\/em> 2013<\/strong>; 50(6):1282-1290.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Stewart, K.L.; Dodds, E.D.; Wysocki, V.H.; Cordes, M.H., A polymetamorphic protein. Protein Sci.<\/em> 2013<\/strong>;22(5):641-9. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Fritz, B.G.; Roberts, S.A.; Ahmed, A.; Breci, L.; Li, W.; Weichsel, A.; Brailey, J.L.; Wysocki, V.H.; Tama, F.; Montfort, W.R., Molecular model of a soluble guanylyl cyclase fragment determined by small-angle X-ray scattering and chemical cross-linking. Biochemistry-Us<\/em>. 2013<\/strong>;52(9):1568-82. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Basha, E.; Jones, C.; Blackwell, A.E.; Cheng, G.; Waters, E.R.; Samsel, K.A.; Siddique, M.; Pett, V.; Wysocki, V.H.; Vierling, E., An unusual dimeric small heat shock protein provides insight into the mechanism of this class of chaperones. J Mol Biol.<\/em> 2013<\/strong>;425(10):1683-96. [Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Ma, X.; Shah, S.; Zhou, M.; Park, C. K.; Wysocki, V. H.; Horton, N. C., Structural Analysis of Activated SgrAI\u2013DNA Oligomers Using Ion Mobility Mass Spectrometry. Biochemistry<\/em> 2013<\/strong>, 52(25): 4373-81.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Quintyn, Royston S.; Zhou, Mowei; Dagan, Shai;\u00a0Finke, John;\u00a0Wysocki, Vicki H., Ligand binding and unfolding of tryptophan synthase revealed by ion mobility-tandem mass spectrometry employing collision and surface induced dissociation. International Journal for Ion Mobility Spectrometry<\/em> 2013<\/strong>, 16(2): 133-143.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Mashalidis, E. H.; Briggs, D. B.; Zhou, M.; Vergara, A. M.; Chhun, J. J.; Ellsworth, R. K.; Giron, R. M.; Rood, J.; Bray, G. A.; Smith, S. R.; Wysocki, V. H.; Tsao, T.-S, High-resolution identification of human adiponectin oligomers and regulation by pioglitazone in type 2 diabetic patients. Analytical Biochemistry<\/em> 2013<\/strong>, 437(2): 150-160.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Ma, Xin; Dagan, Shai; Somogyi, \u00c1rp\u00e1d; Wysocki, Vicki H.; Scaraffia, Patricia Y., Low Mass MS\/MS Fragments of Protonated Amino Acids Used for Distinction of Their 13C- Isotopomers in Metabolic Studies. J. Am. Soc. Mass Spectrometry<\/em> 2013<\/strong>, 24(4): 622-631\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Zhou, Mowei; Dagan, Shai; Wysocki, Vicki H., Impact of Charge State on Gas-Phase Behaviors of Noncovalent Protein Complexes in Collision Induced Dissociation and Surface Induced Dissociation. Analyst <\/em>2013<\/strong>, 138, 1353-1362.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Morrison, Lindsay; Somogyi, Arpad; Wysocki, Vicki H., The influence glutamic acid in protonated b3 \u2192 b2 formation from VGEIG and related analogs. International Journal of Mass Spectrometry<\/em> 2012<\/strong>, 325-327, 139-149.\u00a0[Request reprint \u00a9<\/sup> (pdf)]<\/a><\/p>\n

Zhou, M.; Huang, C.; Wysocki, V. H., Surface-Induced Dissociation of Ion Mobility-Separated Noncovalent Complexes in a Quadrupole\/Time-of-Flight Mass Spectrometer. Anal. Chem. (Washington, DC, U. S.) <\/em>2012,<\/strong> 84<\/em> (14), 6016-6023.\u00a0\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Bush, David R.; Wysocki, Vicki H.; Scaraffia, Patricia Y., Study of the fragmentation of arginine isobutyl ester applied to arginine quantification in Aedes aegypti mosquito excreta. Journal of Mass Spectrometry <\/em>2012<\/strong>, 47(10), 1364-1371.\u00a0[Request reprint\u00a0\u00a9\u00a0(pdf)]<\/a><\/p>\n

Zhou, M.; Dagan, S.; Wysocki, V. H., Protein subunits released by surface collisions of noncovalent complexes: nativelike compact structures revealed by ion mobility mass spectrometry. Angew Chem Int Ed <\/em>2012,<\/strong> 51<\/em> (18), 4336-9.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wolk, D. M.; Kaleta, E. J.; Wysocki, V. H., PCR-electrospray ionization mass spectrometry: the potential to change infectious disease diagnostics in clinical and public health laboratories. J Mol Diagn <\/em>2012,<\/strong> 14<\/em> (4), 295-304.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Mealman, T. D.; Zhou, M.; Affandi, T.; Chacon, K. N.; Aranguren, M. E.; Blackburn, N. J.; Wysocki, V. H.; McEvoy, M. M., N-Terminal Region of CusB Is Sufficient for Metal Binding and Metal Transfer with the Metallochaperone CusF. Biochemistry <\/em>2012,<\/strong> 51<\/em> (34), 6767-6775.\u00a0\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Laskay, Unige A.; Kaleta, Erin J.; Wysocki, Vicki H., \u201cMethods of mass spectrometry in homeland security applications\u201c\u00a0Edited By:Lee, Mike S, Mass Spectrometry Handbook<\/em> 2012<\/strong>, 419-439.\u00a0[Request reprint\u00a0\u00a9\u00a0(pdf)]<\/a><\/p>\n

Li, W.; Wysocki, V. H., ETD fragmentation features improve algorithm. Expert Rev. Proteomics <\/em>2012,<\/strong> 9<\/em> (3), 241-243.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Li, W.; O’Neill, H. A.; Wysocki, V. H., SQID-XLink: Implementation of An Intensity-Incorporated-Algorithm for Cross-linked Peptide Identification. Bioinformatics <\/em>2012<\/strong>.\u00a0[Request reprint\u00a0\u00a9\u00a0(pdf)]<\/a><\/p>\n

Laskay, U. A.; Burg, J.; Kaleta, E. J.; Vilcins, I.-M. E.; Telford, S. R., III; Barbour, A. G.; Wysocki, V. H., Development of a host blood meal database: de novo sequencing of hemoglobin from nine small mammals using mass spectrometry. Biol. Chem. <\/em>2012,<\/strong> 393<\/em> (3), 195-201. \u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Heaton, B. E.; Herrou, J.; Blackwell, A. E.; Wysocki, V. H.; Crosson, S., Molecular structure and function of the novel BrnT\/BrnA toxin-antitoxin system of Brucella abortus. J. Biol. Chem. <\/em>2012,<\/strong> 287<\/em> (15), 12098-12110.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Gucinski, A. C.; Chamot-Rooke, J.; Nicol, E.; Somogyi, A.; Wysocki, V. H., Structural Influences on Preferential Oxazolone versus Diketopiperazine b2+ Ion Formation for Histidine Analogue-Containing Peptides. J. Phys. Chem. A <\/em>2012,<\/strong> 116<\/em> (17), 4296-4304.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Bernier, M. C.; Paizs, B.; Wysocki, V. H., Influence of a gamma amino acid on the structures and reactivity of peptide a 3 ions. Int. J. Mass Spectrom. <\/em>2012,<\/strong> 316-318<\/em>, 259-267.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Zhang, Q.; Perkins, B.; Tan, G.; Wysocki, V. H., The role of proton bridges in selective cleavage of Ser-, Thr-, Cys-, Met-, Asp-, and Asn-containing peptides. Int. J. Mass Spectrom. <\/em>2011,<\/strong> 300<\/em> (2-3), 108-117.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wickramasekara, S.; Neilson, J.; Patel, N.; Breci, L.; Hilderbrand, A.; Maier, R. M.; Wysocki, V., Proteomics analyses of the opportunistic pathogen Burkholderia vietnamiensis using Protein fractionations and mass spectrometry. J. Biomed. Biotechnol. <\/em>2011<\/strong>, 701928, 10 pp.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Mealman, T. D.; Bagai, I.; Singh, P.; Goodlett, D. R.; Rensing, C.; Zhou, H.; Wysocki, V. H.; McEvoy, M. M., Interactions between CusF and CusB Identified by NMR Spectroscopy and Chemical Cross-Linking Coupled to Mass Spectrometry. Biochemistry <\/em>2011,<\/strong> 50<\/em> (13), 2559-2566.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Li, W.; Song, C.; Bailey, D. J.; Tseng, G. C.; Coon, J. J.; Wysocki, V. H., Statistical Analysis of Electron Transfer Dissociation Pairwise Fragmentation Patterns. Anal. Chem. (Washington, DC, U. S.) <\/em>2011,<\/strong> 83<\/em> (24), 9540-9545.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Li, W.; Ji, L.; Goya, J.; Tan, G.; Wysocki, V. H., SQID: An Intensity-Incorporated Protein Identification Algorithm for Tandem Mass Spectrometry. J. Proteome Res. <\/em>2011,<\/strong> 10<\/em> (4), 1593-1602.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Kaleta, E. J.; Clark, A. E.; Johnson, D. R.; Gamage, D. C.; Wysocki, V. H.; Cherkaoui, A.; Schrenzel, J.; Wolk, D. M., Use of PCR coupled with electrospray ionization mass spectrometry for rapid identification of bacterial and yeast bloodstream pathogens from blood culture bottles. J. Clin. Microbiol. <\/em>2011,<\/strong> 49<\/em> (1), 345-353.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Kaleta, E. J.; Clark, A. E.; Cherkaoui, A.; Wysocki, V. H.; Ingram, E. L.; Schrenzel, J.; Wolk, D. M., Comparative analysis of PCR-electrospray ionization\/mass spectrometry (MS) and MALDI-TOF\/MS for the identification of bacteria and yeast from positive blood culture bottles. Clin. Chem. (Washington, DC, U. S.) <\/em>2011,<\/strong> 57<\/em> (7), 1057-1067.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Dodds, E. D.; Blackwell, A. E.; Jones, C. M.; Holso, K. L.; O’Brien, D. J.; Cordes, M. H. J.; Wysocki, V. H., Determinants of gas-phase disassembly behavior in homodimeric protein complexes with related yet divergent structures. Anal. Chem. (Washington, DC, U. S.) <\/em>2011,<\/strong> 83<\/em> (10), 3881-3889.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Blackwell, A. E.; Dodds, E. D.; Bandarian, V.; Wysocki, V. H., Revealing the Quaternary Structure of a Heterogeneous Noncovalent Protein Complex through Surface-Induced Dissociation. Anal. Chem. (Washington, DC, U. S.) <\/em>2011,<\/strong> 83<\/em> (8), 2862-2865.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Scaraffia, P. Y.; Zhang, Q.; Thorson, K.; Wysocki, V. H.; Miesfeld, R. L., Differential ammonia metabolism in Aedes aegypti fat body and midgut tissues. J. Insect Physiol. <\/em>2010,<\/strong> 56<\/em> (9), 1040-1049.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Kiesler, P.; Haynes, P. A.; Shi, L.; Kao, P. N.; Wysocki, V. H.; Vercelli, D., NF45 and NF90 Regulate HS4-dependent Interleukin-13 Transcription in T Cells. J. Biol. Chem. <\/em>2010,<\/strong> 285<\/em> (11), 8256-8267.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Jiang, W.; Wysocki, V. H.; Dodds, E. D.; Miesfeld, R. L.; Scaraffia, P. Y., Differentiation and quantification of C1 and C2 13C-labeled glucose by tandem mass spectrometry. Anal. Biochem. <\/em>2010,<\/strong> 404<\/em> (1), 40-44.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Hua, Y.; Dagan, S.; Wickramasekara, S.; Boday, D. J.; Wysocki, V. H., Analysis of deprotonated acids with silicon nanoparticle-assisted laser desorption\/ ionization mass spectrometry. J. Mass Spectrom. <\/em>2010,<\/strong> 45<\/em> (12), 1394-1401.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Gucinski, A. C.; Somogyi, A.; Chamot-Rooke, J.; Wysocki, V. H., Separation and Identification of Structural Isomers by Quadrupole Collision-Induced Dissociation-Hydrogen\/Deuterium Exchange-Infrared Multiphoton Dissociation (QCID-HDX-IRMPD). J. Am. Soc. Mass Spectrom. <\/em>2010,<\/strong> 21<\/em> (8), 1329-1338.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Gucinski, A. C.; Dodds, E. D.; Li, W.; Wysocki, V. H., Understanding and exploiting peptide fragment ion intensities using experimental and informatic approaches. Methods Mol. Biol. (Totowa, NJ, U. S.) <\/em>2010,<\/strong> 604<\/em> (Proteome Bioinformatics), 73-94.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Basha, E.; Jones, C.; Wysocki, V.; Vierling, E., Mechanistic Differences between Two Conserved Classes of Small Heat Shock Proteins Found in the Plant Cytosol. J. Biol. Chem. <\/em>2010,<\/strong> 285<\/em> (15), 11489-11497.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Yoon, S. H.; Gamage, C. M.; Gillig, K. J.; Wysocki, V. H., Kinetics of Surface-Induced Dissociation of N(CH3)4\u00b7+ and N(CD3)4\u00b7+ Using Silicon Nanoparticle Assisted Laser Desorption\/Ionization and Laser Desorption\/Ionization. J. Am. Soc. Mass Spectrom. <\/em>2009,<\/strong> 20<\/em> (6), 957-964.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wolk, D. M.; Blyn, L. B.; Hall, T. A.; Sampath, R.; Ranken, R.; Ivy, C.; Melton, R.; Matthews, H.; White, N.; Li, F.; Harpin, V.; Ecker, D. J.; Limbago, B.; McDougal, L. K.; Wysocki, V. H.; Cai, M.; Carroll, K. C., Pathogen profiling: rapid molecular characterization of Staphylococcus aureus by PCR\/electrospray ionization-mass spectrometry and correlation with phenotype. J. Clin. Microbiol. <\/em>2009,<\/strong> 47<\/em> (10), 3129-3137.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Perkins, B. R.; Chamot-Rooke, J.; Yoon, S. H.; Gucinski, A. C.; Somogyi, A.; Wysocki, V. H., Evidence of Diketopiperazine and Oxazolone Structures for HA b2+ Ion. J. Am. Chem. Soc. <\/em>2009,<\/strong> 131<\/em> (48), 17528-17529.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Joubert, J. R.; Smith, K. A.; Johnson, E.; Keogh, J. P.; Wysocki, V. H.; Gale, B. K.; Conboy, J. C.; Saavedra, S. S., Stable, Ligand-Doped, Poly(bis-SorbPC) Lipid Bilayer Arrays for Protein Binding and Detection. ACS Appl. Mater. Interfaces <\/em>2009,<\/strong> 1<\/em> (6), 1310-1315.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Johnson, E. M.; Ellis, W. R.; Powers, L. S.; Wysocki, V. H., Affinity Capture Mass Spectrometry of Biomarker Proteins Using Peptide Ligands from Biopanning. Anal. Chem. (Washington, DC, U. S.) <\/em>2009,<\/strong> 81<\/em> (15), 5999-6005.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Hall, T. A.; Sampath, R.; Blyn, L. B.; Ranken, R.; Ivy, C.; Melton, R.; Matthews, H.; White, N.; Li, F.; Harpin, V.; Ecker, D. J.; McDougal, L. K.; Limbago, B.; Ross, T.; Wolk, D. M.; Wysocki, V.; Carroll, K. C., Rapid molecular genotyping and clonal complex assignment of Staphylococcus aureus isolates by PCR coupled to electrospray ionization-mass spectrometry. J. Clin. Microbiol. <\/em>2009,<\/strong> 47<\/em> (6), 1733-1741.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Galhena, A. S.; Jones, C. M.; Wysocki, V. H., Influence of cluster size and ion activation method on the dissociation of cesium iodide clusters. Int. J. Mass Spectrom. <\/em>2009,<\/strong> 287<\/em> (1-3), 105-113.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Dodatko, T.; Akoachere, M.; Muehlbauer, S. M.; Helfrich, F.; Howerton, A.; Ross, C.; Wysocki, V.; Brojatsch, J.; Abel-Santos, E., Bacillus cereus spores release alanine that synergizes with inosine to promote germination. PLoS One <\/em>2009,<\/strong> 4<\/em> (7), e6398.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Dagan, S.; Hua, Y.; Boday, D. J.; Somogyi, A.; Wysocki, R. J.; Wysocki, V. H., Internal energy deposition with silicon nanoparticle-assisted laser desorption\/ionization (SPALDI) mass spectrometry. Int. J. Mass Spectrom. <\/em>2009,<\/strong> 283<\/em> (1-3), 200-205.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Briggs, D. B.; Jones, C. M.; Mashalidis, E. H.; Nunez, M.; Hausrath, A. C.; Wysocki, V. H.; Tsao, T.-S., Disulfide-Dependent Self-Assembly of Adiponectin Octadecamers from Trimers and Presence of Stable Octadecameric Adiponectin Lacking Disulfide Bonds in Vitro. Biochemistry <\/em>2009,<\/strong> 48<\/em> (51), 12345-12357.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Beardsley, R. L.; Jones, C. M.; Galhena, A. S.; Wysocki, V. H., Noncovalent Protein Tetramers and Pentamers with “n” Charges Yield Monomers with n\/4 and n\/5 Charges. Anal. Chem. (Washington, DC, U. S.) <\/em>2009,<\/strong> 81<\/em> (4), 1347-1356.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Alloway, D. M.; Graham, A. L.; Yang, X.; Mudalige, A.; Colorado, R.; Wysocki, V. H.; Pemberton, J. E.; Randall, L. T.; Wysocki, R. J.; Armstrong, N. R., Tuning the Effective Work Function of Gold and Silver Using \u03c9-Functionalized Alkanethiols: Varying Surface Composition through Dilution and Choice of Terminal Groups. J. Phys. Chem. C <\/em>2009,<\/strong> 113<\/em> (47), 20328-20334.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Yoon, S. H.; Chamot-Rooke, J.; Perkins, B. R.; Hilderbrand, A. E.; Poutsma, J. C.; Wysocki, V. H., IRMPD Spectroscopy Shows That AGG Forms an Oxazolone b2+ Ion. J. Am. Chem. Soc. <\/em>2008,<\/strong> 130<\/em> (52), 17644-17645.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Joyce, K. E.; Jones, C. M.; Beardsley, R. L., Surface-Induced Dissociation of Small Molecules, Peptides, and Non-Covalent Protein Complexes. J. Am. Soc. Mass Spectrom. <\/em>2008,<\/strong> 19<\/em> (2), 190-208.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Jones, C. M.; Galhena, A. S.; Blackwell, A. E., Surface-Induced Dissociation Shows Potential to Be More Informative Than Collision-Induced Dissociation for Structural Studies of Large Systems. J. Am. Soc. Mass Spectrom. <\/em>2008,<\/strong> 19<\/em> (7), 903-913.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wickramasekara, S.; Bunikis, J.; Wysocki, V.; Barbour, A. G., Identification of residual blood proteins in ticks by mass spectrometry proteomics. Emerging Infect. Dis. <\/em>2008,<\/strong> 14<\/em> (8), 1273-1275.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Scaraffia, P. Y.; Tan, G.; Isoe, J.; Wysocki, V. H.; Wells, M. A.; Miesfeld, R. L., Discovery of an alternate metabolic pathway for urea synthesis in adult Aedes aegypti mosquitoes. Proc. Natl. Acad. Sci. U. S. A. <\/em>2008,<\/strong> 105<\/em> (2), 518-523.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Ochoa-Herrera, V.; Sierra-Alvarez, R.; Somogyi, A.; Jacobsen, N. E.; Wysocki, V. H.; Field, J. A., Reductive Defluorination of Perfluorooctane Sulfonate. Environ. Sci. Technol. <\/em>2008,<\/strong> 42<\/em> (9), 3260-3264.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Huang, Y.; Tseng, G. C.; Yuan, S.; Pasa-Tolic, L.; Lipton, M. S.; Smith, R. D.; Wysocki, V. H., A Data-Mining Scheme for Identifying Peptide Structural Motifs Responsible for Different MS\/MS Fragmentation Intensity Patterns. J. Proteome Res. <\/em>2008,<\/strong> 7<\/em> (1), 70-79.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Galhena, A. S.; Dagan, S.; Jones, C. M.; Beardsley, R. L.; Wysocki, V. H., Surface-induced dissociation of peptides and protein complexes in a quadrupole\/time-of-flight mass spectrometer. Anal. Chem. (Washington, DC, U. S.) <\/em>2008,<\/strong> 80<\/em> (5), 1425-1436.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Cheng, G.; Basha, E.; Wysocki, V. H.; Vierling, E., Insights into Small Heat Shock Protein and Substrate Structure during Chaperone Action Derived from Hydrogen\/Deuterium Exchange and Mass Spectrometry. J. Biol. Chem. <\/em>2008,<\/strong> 283<\/em> (39), 26634-26642.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wen, X.; Dagan, S.; Wysocki, V. H., Small-Molecule Analysis with Silicon-Nanoparticle-Assisted Laser Desorption\/Ionization Mass Spectrometry. Anal. Chem. <\/em>2007,<\/strong> 79<\/em> (2), 434-444.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Rohrbough, J. G.; Galgiani, J. N.; Wysocki, V. H., The application of proteomic techniques to fungal protein identification and quantification. Ann N Y Acad Sci <\/em>2007,<\/strong> 1111<\/em>, 133-46.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Schmader, T.; Whitehead, J.; Wysocki, V. H., A Linguistic Comparison of Letters of Recommendation for Male and Female Chemistry and Biochemistry Job Applicants.\u00a0Sex Roles<\/em>. 2007<\/strong>;57(7-8):509\u2013514. doi:10.1007\/s11199-007-9291-4.\u00a0\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Cheng, G.; Zhang, Q.; Herrmann, K. A.; Beardsley, R. L.; Hilderbrand, A. E. In Peptide fragmentation overview<\/em>, John Wiley & Sons, Inc.: 2006<\/strong>; pp 279-300.<\/p>\n

Smith, L. L.; Herrmann, K. A.; Wysocki, V. H., Investigation of Gas Phase Ion Structure for Proline-Containing b2 Ion. J. Am. Soc. Mass Spectrom. <\/em>2006,<\/strong> 17<\/em> (1), 20-28.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Scaraffia, P. Y.; Zhang, Q.; Wysocki, V. H.; Isoe, J.; Wells, M. A., Analysis of whole body ammonia metabolism in Aedes aegypti using [15N]-labeled compounds and mass spectrometry. Insect Biochem. Mol. Biol. <\/em>2006,<\/strong> 36<\/em> (8), 614-622.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Jones, C. M.; Beardsley, R. L.; Galhena, A. S.; Dagan, S.; Cheng, G.; Wysocki, V. H., Symmetrical Gas-Phase Dissociation of Noncovalent Protein Complexes via Surface Collisions. J. Am. Chem. Soc. <\/em>2006,<\/strong> 128<\/em> (47), 15044-15045.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Herrmann, K. A.; Kuppannan, K.; Wysocki, V. H., Fragmentation of doubly-protonated peptide ion populations labeled by H\/D exchange with CD3OD. Int. J. Mass Spectrom. <\/em>2006,<\/strong> 249\/250<\/em>, 93-105.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Fernandez, F. M.; Wysocki, V. H.; Futrell, J. H.; Laskin, J., Protein Identification via Surface-Induced Dissociation in an FT-ICR Mass Spectrometer and a Patchwork Sequencing Approach. J. Am. Soc. Mass Spectrom. <\/em>2006,<\/strong> 17<\/em> (5), 700-709.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Cheng, G.; Wysocki, V. H.; Cusanovich, M. A., Local Stability of Rhodobacter capsulatus Cytochrome c2 Probed by Solution Phase Hydrogen\/Deuterium Exchange and Mass Spectrometry. J. Am. Soc. Mass Spectrom. <\/em>2006,<\/strong> 17<\/em> (11), 1518-1525.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Cheng, G.; Cusanovich, M. A.; Wysocki, V. H., Properties of the Dark and Signaling States of Photoactive Yellow Protein Probed by Solution Phase Hydrogen\/Deuterium Exchange and Mass Spectrometry. Biochemistry <\/em>2006,<\/strong> 45<\/em> (39), 11744-11751.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Zhang, Q.; Wysocki, V. H.; Scaraffia, P. Y.; Wells, M. A., Fragmentation Pathway for Glutamine Identification: Loss of 73 Da from Dimethylformamidine Glutamine Isobutyl Ester. J. Am. Soc. Mass Spectrom. <\/em>2005,<\/strong> 16<\/em> (7), 1192-1203.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Resing, K. A.; Zhang, Q.; Cheng, G., Mass spectrometry of peptides and proteins. Methods (San Diego, CA, U. S.) <\/em>2005,<\/strong> 35<\/em> (3), 211-222.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Komaromi, I.; Somogyi, A.; Wysocki, V. H., Proton migration and its effect on the MS fragmentation of N-acetyl OMe proline: MS\/MS experiments and ab initio and density functional calculations. Int. J. Mass Spectrom. <\/em>2005,<\/strong> 241<\/em> (2-3), 315-323.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Huang, Y.; Triscari, J. M.; Tseng, G. C.; Pasa-Tolic, L.; Lipton, M. S.; Smith, R. D.; Wysocki, V. H., Statistical Characterization of the Charge State and Residue Dependence of Low-Energy CID Peptide Dissociation Patterns. Anal. Chem. <\/em>2005,<\/strong> 77<\/em> (18), 5800-5813.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Herrmann, K. A.; Wysocki, V. H.; Vorpagel, E. R., Computational Investigation and Hydrogen\/Deuterium Exchange of the Fixed Charge Derivative Tris(2,4,6-Trimethoxyphenyl) Phosphonium: Implications for the Aspartic Acid Cleavage Mechanism. J. Am. Soc. Mass Spectrom. <\/em>2005,<\/strong> 16<\/em> (7), 1067-1080.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Herrmann, K. A.; Somogyi, A.; Wysocki, V. H.; Drahos, L.; Vekey, K., Combination of Sustained Off-Resonance Irradiation and On-Resonance Excitation in FT-ICR. Anal. Chem. <\/em>2005,<\/strong> 77<\/em> (23), 7626-7638.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Tsaprailis, G.; Nair, H.; Zhong, W.; Kuppannan, K.; Futrell, J. H.; Wysocki, V. H., A mechanistic investigation of the enhanced cleavage at histidine in the gas-phase dissociation of protonated peptides. Anal. Chem. <\/em>2004,<\/strong> 76<\/em> (7), 2083-2094.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Tabb, D. L.; Huang, Y.; Wysocki, V. H.; Yates, J. R., III, Influence of basic residue content on fragment ion peak intensities in low-energy collision-induced dissociation spectra of peptides. Anal. Chem. <\/em>2004,<\/strong> 76<\/em> (5), 1243-1248.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Huang, Y.; Triscari, J. M.; Pasa-Tolic, L.; Anderson, G. A.; Lipton, M. S.; Smith, R. D.; Wysocki, V. H., Dissociation behavior of doubly-charged tryptic peptides: Correlation of gas-phase cleavage abundance with Ramachandran plots. J. Am. Chem. Soc. <\/em>2004,<\/strong> 126<\/em> (10), 3034-3035.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Gamage, C. M.; Fernandez, F. M.; Kuppannan, K.; Wysocki, V. H., Submicrosecond Surface-Induced Dissociation of Peptide Ions in a MALDI TOF MS. Anal. Chem. <\/em>2004,<\/strong> 76<\/em> (17), 5080-5091.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Abeytunga, D. T. U.; Glick, J. J.; Gibson, N. J.; Oland, L. A.; Somogyi, A.; Wysocki, V. H.; Polt, R., Presence of unsaturated sphingomyelins and changes in their composition during the life cycle of the moth Manduca sexta. J. Lipid Res. <\/em>2004,<\/strong> 45<\/em> (7), 1221-1231.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wyttenbach, T.; Paizs, B.; Barran, P.; Breci, L.; Liu, D.; Suhai, S.; Wysocki, V. H.; Bowers, M. T., The Effect of the Initial Water of Hydration on the Energetics, Structures, and H\/D Exchange Mechanism of a Family of Pentapeptides: An Experimental and Theoretical Study. J. Am. Chem. Soc. <\/em>2003,<\/strong> 125<\/em> (45), 13768-13775.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Tabb, D. L.; Smith, L. L.; Breci, L. A.; Wysocki, V. H.; Lin, D.; Yates, J. R., III, Statistical characterization of ion trap tandem mass spectra from doubly charged tryptic peptides. Anal. Chem. <\/em>2003,<\/strong> 75<\/em> (5), 1155-1163.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Smith, D. L.; Selvan, R.; Wysocki, V. H., Reactive Ion Scattering Spectrometry of Mixed Methyl- and Hydroxy-Terminated Alkanethiolate Self-Assembled Monolayers. Langmuir <\/em>2003,<\/strong> 19<\/em> (18), 7302-7306.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Fernandez, F. M.; Smith, L. L.; Kuppannan, K.; Yang, X.; Wysocki, V. H., Peptide sequencing using a patchwork approach and surface-induced dissociation in sector-TOF and dual quadrupole mass spectrometers. J. Am. Soc. Mass Spectrom. <\/em>2003,<\/strong> 14<\/em> (12), 1387-1401.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Breci, L. A.; Tabb, D. L.; Yates, J. R., III; Wysocki, V. H., Cleavage N-Terminal to Proline: Analysis of a Database of Peptide Tandem Mass Spectra. Anal. Chem. <\/em>2003,<\/strong> 75<\/em> (9), 1963-1971.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Alloway, D. M.; Hofmann, M.; Smith, D. L.; Gruhn, N. E.; Graham, A. L.; Colorado, R., Jr.; Wysocki, V. H.; Lee, T. R.; Lee, P. A.; Armstrong, N. R., Interface Dipoles Arising from Self-Assembled Monolayers on Gold: UV-Photoemission Studies of Alkanethiols and Partially Fluorinated Alkanethiols. J. Phys. Chem. B <\/em>2003,<\/strong> 107<\/em> (42), 11690-11699.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Williams, E. R.; Editors, Special Issue: Structure of Biological Molecules<\/em>. Elseier: 2002; p 294 pp.<\/p>\n

Williams, E. R.; Wysocki, V. H., Foreword. Int. J. Mass Spectrom. <\/em>2002,<\/strong> 219<\/em> (1), vii-viii.<\/p>\n

Somogyi, A.; Smith, D. L.; Wysocki, V. H.; Colorado, R.; Lee, T. R., Neutralization of methyl cation via chemical reactions in low-energy ion-surface collisions with fluorocarbon and hydrocarbon self-assembled monolayer films. J. Am. Soc. Mass Spectrom. <\/em>2002,<\/strong> 13<\/em> (10), 1151-1161.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Smith, D. L.; Wysocki, V. H.; Colorado, R., Jr.; Shmakova, O. E.; Graupe, M.; Lee, T. R., Low-Energy Ion-Surface Collisions Characterize Alkyl- and Fluoroalkyl-Terminated Self-Assembled Monolayers on Gold. Langmuir <\/em>2002,<\/strong> 18<\/em> (10), 3895-3902.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Huang, Y.; Wysocki, V. H.; Tabb, D. L.; Yates, J. R., The influence of histidine on cleavage C-terminal to acidic residues in doubly protonated tryptic peptides. Int. J. Mass Spectrom. <\/em>2002,<\/strong> 219<\/em> (1), 233-244.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Nikolaev, E. N.; Somogyi, A.; Smith, D. L.; Gu, C.; Wysocki, V. H.; Martin, C. D.; Samuelson, G. L., Implementation of low-energy surface-induced dissociation (eV SID) and high-energy collision-induced dissociation (keV CID) in a linear sector-TOF hybrid tandem mass spectrometer. Int. J. Mass Spectrom. <\/em>2001,<\/strong> 212<\/em> (1-3), 535-551.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Tsaprailis, G.; Smith, L. L.; Breci, L. A., Mobile and localized protons: a framework for understanding peptide dissociation. J. Mass Spectrom. <\/em>2000,<\/strong> 35<\/em> (12), 1399-1406.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Tsaprailis, G.; Somogyi, A.; Nikolaev, E. N.; Wysocki, V. H., Refining the model for selective cleavage at acidic residues in arginine-containing protonated peptides. Int. J. Mass Spectrom. <\/em>2000,<\/strong> 195\/196<\/em>, 467-479.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Martin, C. D.; Samuelson, G. L.; Owen, E. E.; Wysocki, V. H.; Somogyi, A.; Nikolaev, E. N.; Gu, C. Mass spectrometer for molecular structural analysis using surface induced dissociation. WO2000077824A1, 2000.<\/p>\n

Gu, C.; Tsaprailis, G.; Breci, L.; Wysocki, V. H., Selective Gas-Phase Cleavage at the Peptide Bond C-Terminal to Aspartic Acid in Fixed-Charge Derivatives of Asp-Containing Peptides. Anal. Chem. <\/em>2000,<\/strong> 72<\/em> (23), 5804-5813.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Angelico, V. J.; Mitchell, S. A.; Wysocki, V. H., Low-Energy Ion-Surface Reactions of Pyrazine with Two Classes of Self-Assembled Monolayers: Influence of Alkyl Chain Orientation. Anal. Chem. <\/em>2000,<\/strong> 72<\/em> (11), 2603-2608.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Tsaprailis, G.; Nair, H.; Somogyi, A.; Wysocki, V. H.; Zhong, W.; Futrell, J. H.; Summerfield, S. G.; Gaskell, S. J., Influence of Secondary Structure on the Fragmentation of Protonated Peptides. J. Am. Chem. Soc. <\/em>1999,<\/strong> 121<\/em> (22), 5142-5154.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Gu, C.; Wysocki, V. H.; Harada, A.; Takaya, H.; Kumadaki, I., Dissociative and Reactive Hyperthermal Ion-Surface Collisions with Langmuir-Blodgett Films Terminated by CF3(CH2)n-, n-Perfluoroalkyl, or n-Alkyl Groups. J. Am. Chem. Soc. <\/em>1999,<\/strong> 121<\/em> (45), 10554-10562.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Gu, C.; Somogyi, A.; Wysocki, V. H.; Medzihradszky, K. F., Fragmentation of protonated oligopeptides XLDVLQ (X=L, H, K or R) by surface induced dissociation: additional evidence for the ‘mobile proton’ model. Anal. Chim. Acta <\/em>1999,<\/strong> 397<\/em> (1-3), 247-256.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

De, M.-G. J.; Gu, C.; Somogyi, A.; Wysocki, V. H.; Kistemaker, P. G.; Weeding, T. L., Surface-induced dissociation of singly and multiply protonated polypropylenamine dendrimers. J. Am. Soc. Mass Spectrom. <\/em>1999,<\/strong> 10<\/em> (5), 414-422.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Schaaff, T. G.; Qu, Y.; Farrell, N.; Wysocki, V. H., Investigation of the trans effect in the fragmentation of dinuclear platinum complexes by electrospray ionization surface-induced dissociation tandem mass spectrometry. J. Mass Spectrom. <\/em>1998,<\/strong> 33<\/em> (5), 436-443.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Nair, H.; Wysocki, V. H., Are peptides without basic residues protonated primarily at the amino terminus? Int. J. Mass Spectrom. Ion Processes <\/em>1998,<\/strong> 174<\/em> (1-3), 95-100.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Futrell, J. H.; Zhong, W.; Nikolaev, E. N.; Wysocki, V. H., Tandem Fourier transform mass spectrometry studies of surface-induced dissociation of benzene monomer and dimer ions on a self-assembled fluoroalkanethiolate monolayer surface. Adv. Mass Spectrom. <\/em>1998,<\/strong> 14<\/em>, A065390\/1-A065390\/21.<\/p>\n

De, M.-G. J.; Somogyi, A.; Wysocki, V. H.; Kistemaker, P. G.; Weeding, T. L., Surface-induced dissociation of diphenyl ether. Int. J. Mass Spectrom. Ion Processes <\/em>1998,<\/strong> 174<\/em> (1-3), 81-94.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

De, M.-G. J.; Gu, C.; Somogyi, A.; Wysocki, V. H.; Kistemaker, P. G.; Weeding, T. L., ESI\/SID of polypropylenamine dendrimers. Adv. Mass Spectrom. <\/em>1998,<\/strong> 14<\/em>, A077590\/1-A077590\/11.<\/p>\n

Zhong, W.; Nikolaev, E. N.; Futrell, J. H.; Wysocki, V. H., Tandem Fourier Transform Mass Spectrometry Studies of Surface-Induced Dissociation of Benzene Monomer and Dimer on Self-Assembled Fluorinated Alkanethiolate Monolayer Surface. Anal. Chem. <\/em>1997,<\/strong> 69<\/em> (13), 2496-2503.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Kane, T. E.; Angelico, V. J.; Wysocki, V. H., Neutralization of Polyatomic Ions at Self-Assembled Monolayer Surfaces before and after Electrodeposition of Poly(phenylene oxide). Langmuir <\/em>1997,<\/strong> 13<\/em> (25), 6722-6725.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Gu, C.; Wysocki, V. H., Ion-Surface Reactions Involving Isotopically Labeled Langmuir-Blodgett Films. J. Am. Chem. Soc. <\/em>1997,<\/strong> 119<\/em> (49), 12010-12011.\u00a0\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Vekey, K.; Somogyi, A.; Wysocki, V. H., Average activation energies of low-energy fragmentation processes of protonated peptides determined by a new approach. Rapid Commun. Mass Spectrom. <\/em>1996,<\/strong> 10<\/em> (8), 911-918.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Nair, H.; Somogyi, A.; Wysocki, V. H., Effect of alkyl substitution at the amide nitrogen on amide bond cleavage: electrospray ionization\/surface-induced dissociation fragmentation of substance P and two alkylated analogs. J. Mass Spectrom. <\/em>1996,<\/strong> 31<\/em> (10), 1141-1148.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Hayward, M. J.; Park, F. D. S.; Phelan, L. M.; Bernasek, S. L.; Somogyi, A.; Wysocki, V. H., Examination of Sputtered Ion Mechanisms Leading to the Formation of C7H7+ during Surface Induced Dissociation (SID) Tandem Mass Spectrometry (MS\/MS) of Benzene Molecular Cations. J. Am. Chem. Soc. <\/em>1996,<\/strong> 118<\/em> (35), 8375-8380.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Dongre, A. R.; Somogyi, A.; Wysocki, V. H., Surface-induced dissociation: an effective tool to probe structure, energetics and fragmentation mechanisms of protonated peptides. J. Mass Spectrom. <\/em>1996,<\/strong> 31<\/em> (4), 339-50.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Dongre, A. R.; Jones, J. L.; Somogyi, A.; Wysocki, V. H., Influence of Peptide Composition, Gas-Phase Basicity, and Chemical Modification on Fragmentation Efficiency: Evidence for the Mobile Proton Model. J. Am. Chem. Soc. <\/em>1996,<\/strong> 118<\/em> (35), 8365-8374.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Vekey, K.; Somogyi, A.; Wysocki, V. H., Internal energy distribution of benzene molecular ions in surface-induced dissociation. J. Mass Spectrom. <\/em>1995,<\/strong> 30<\/em> (1), 212-17.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Meot-Ner, M.; Dongre, A. R.; Somogyi, A.; Wysocki, V. H., Thermal decomposition kinetics of protonated peptides and peptide dimers, and comparison with surface-induced dissociation. Rapid Commun. Mass Spectrom. <\/em>1995,<\/strong> 9<\/em> (9), 829-36.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Kane, T. E.; Angelico, V. J.; Wysocki, V. H., Use of condensation figures to image low-energy ion beam damage of monolayer films. [Erratum to document cited in CA121:239123]. Anal. Chem. <\/em>1995,<\/strong> 67<\/em> (5), 1019.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Jones, J. L.; Dongre, A. R.; Somogyi, A.; McCormack, A. L. In Surface-induced dissociation of peptides<\/em>, Wiley: 1994; pp 249-54.<\/p>\n

Somogyi, A.; Wysocki, V. H.; Mayer, I., The effect of protonation site on bond strengths in simple peptides: application of Ab initio and modified neglect of differential overlap bond orders and modified neglect of differential overlap energy partitioning. J. Am. Soc. Mass Spectrom. <\/em>1994,<\/strong> 5<\/em> (8), 704-17.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Kane, T. E.; Wysocki, V. H., Surface-induced dissociation and ion-surface reactions at insulating surfaces. Int. J. Mass Spectrom. Ion Processes <\/em>1994,<\/strong> 140<\/em>, 177-84.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Jones, J. L.; Dongre, A. R.; Somogyi, A.; Wysocki, V. H., Sequence Dependence of Peptide Fragmentation Efficiency Curves Determined by Electrospray Ionization\/Surface-Induced Dissociation Mass Spectrometry. J. Am. Chem. Soc. <\/em>1994,<\/strong> 116<\/em> (18), 8368-9.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Dongre, A. R.; Wysocki, V. H., Linkage position determination of lithium-cationized disaccharides by surface-induced dissociation tandem mass spectrometry. Org. Mass Spectrom. <\/em>1994,<\/strong> 29<\/em> (11), 700-2.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Cooks, R. G.; Ast, T.; Pradeep, T.; Wysocki, V., Reactions of ions with organic surfaces. Acc. Chem. Res. <\/em>1994,<\/strong> 27<\/em> (11), 316-23.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Somogyi, A.; Kane, T. E.; Wysocki, V. H., Reactions between doubly charged [C6H6]2+ ions and self-assembled monolayer surfaces. Org. Mass Spectrom. <\/em>1993,<\/strong> 28<\/em> (3), 283-4.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Somogyi, A.; Kane, T. E.; Ding, J. M.; Wysocki, V. H., Reactive collisions of benzene ion C6H6\u2022+ and C6D6\u2022+ at self-assembled monolayer films prepared on gold from n-alkane thiols and a fluorinated alkanethiol: the influence of chain length on the reactivity of the films and the neutralization of the projectile. J. Am. Chem. Soc. <\/em>1993,<\/strong> 115<\/em> (12), 5275-83.\u00a0\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

McCormack, A. L.; Somogyi, A.; Dongre, A. R.; Wysocki, V. H., Fragmentation of protonated peptides: surface-induced dissociation in conjunction with a quantum mechanical approach. Anal. Chem. <\/em>1993,<\/strong> 65<\/em> (20), 2859-72.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Kane, T. E.; Somogyi, A.; Wysocki, V. H., Reactive ion-surface collisions: application of ionized acetone-d6, DMSO-d6 and pyridine-d5 as probes for the characterization of self-assembled monolayer films on gold. Org. Mass Spectrom. <\/em>1993,<\/strong> 28<\/em> (12), 1665-73.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Callahan, J. H.; Somogyi, A.; Wysocki, V. H., Collisions of fullerene C60+\u2022 and C602+ at fluorinated and non-fluorinated self-assembled monolayer films. Rapid Commun. Mass Spectrom. <\/em>1993,<\/strong> 7<\/em> (8), 693-9.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Ding, J. M.; Jones, J. L.; Callahan, J. H.; King, F. L., Surface-induced dissociation in tandem quadrupole mass spectrometers: a comparison of three designs. J. Am. Soc. Mass Spectrom. <\/em>1992,<\/strong> 3<\/em> (1), 27-32.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H., Triple quadrupole mass spectrometry. NATO ASI Ser., Ser. C <\/em>1992,<\/strong> 353<\/em> (Mass Spectrom. Biol. Sci.: Tutorial), 59-77.<\/p>\n

Ross, M. M.; Callahan, J. H.; King, F. L.; Wysocki, V. H.; Bach, S. B. Cluster\/surface interactions and cluster\/matrix deposition<\/em>; Virginia Commonw. Univ.: 1992; p 8 pp.<\/p>\n

McCormack, A. L.; Jones, J. L.; Wysocki, V. H., Surface-induced dissociation of multiply protonated peptides. J. Am. Soc. Mass Spectrom. <\/em>1992,<\/strong> 3<\/em> (8), 859-62.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

McCormack, A. L.; Jones, J. L.; Wysocki, V. H. Surface-induced dissociation of multiply protonated peptides<\/em>; Virginia Commonw. Univ.: 1992; p 17 pp.<\/p>\n

Wysocki, V. H.; Ross, M. M., Charge-remote fragmentation of gas-phase ions: mechanistic and energetic considerations in the dissociation of long-chain functionalized alkanes and alkenes. Int. J. Mass Spectrom. Ion Processes <\/em>1991,<\/strong> 104<\/em> (3), 179-211.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Jones, J. L.; Ding, J. M., Polyatomic ion\/surface collisions at self-assembled monolayers films. J. Am. Chem. Soc. <\/em>1991,<\/strong> 113<\/em> (23), 8969-70.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Ross, M. M.; Callahan, J. H.; King, F. L.; Wysocki, V. H.; Bach, S. B. H.; Nelson, H. H.; Baronavski, A. P.; McElvany, S. W., Cluster\/surface interactions and cluster\/matrix deposition. Mater. Res. Soc. Symp. Proc. <\/em>1991,<\/strong> 206<\/em> (Clusters Cluster-Assem. Mater.), 363-8.<\/p>\n

Wysocki, V. H.; Kenttamaa, H. I., Collisional activation of distonic radical cations and their conventional isomers in quadrupole tandem mass spectrometry. J. Am. Chem. Soc. <\/em>1990,<\/strong> 112<\/em> (13), 5110-16.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Schey, K. L.; Kenttamaa, H. I.; Wysocki, V. H.; Cooks, R. G., Low-energy collisional activation of polyatomic ions with different target gases. Int. J. Mass Spectrom. Ion Processes <\/em>1989,<\/strong> 90<\/em> (1), 71-83.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Ross, M. M.; Horning, S. R.; Cooks, R. G., Remote-site (charge-remote) fragmentation. Rapid Commun. Mass Spectrom. <\/em>1988,<\/strong> 2<\/em> (10), 214-17.\u00a0[Request reprint \u00a9 (pdf)]<\/a><\/p>\n

Wysocki, V. H.; Kenttamaa, H. I.; Cooks, R. G., Energetics of activation of tetracarbonylferrate(1-) and pentacarbonylchromate(1-) in gaseous collisions. J. Phys. Chem. <\/em>1988,<\/strong> 92<\/em> (22), 6465-9.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Bier, M. E.; Cooks, R. G., Internal energy requirements for remote site fragmentation. Org. Mass Spectrom. <\/em>1988,<\/strong> 23<\/em> (9), 627-33.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Brodbelt, J. S.; Wysocki, V. H.; Cooks, R. G., Thermochemical vs. kinetic control of reactions in an ion trap mass spectrometer. Org. Mass Spectrom. <\/em>1988,<\/strong> 23<\/em> (1), 54-6.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Kenttamaa, H. I.; Cooks, R. G., Internal energy distributions of isolated ions after activation by various methods. Int. J. Mass Spectrom. Ion Processes <\/em>1987,<\/strong> 75<\/em> (2), 181-208.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H. Internal energy effects in mass spectrometry. 1987.<\/p>\n

DeKrey, M. J.; Kenttamaa, H. I.; Wysocki, V. H.; Cooks, R. G., Energy deposition in iron pentacarbonyl cation radical upon collision with a metal surface. Org. Mass Spectrom. <\/em>1986,<\/strong> 21<\/em> (4), 193-5.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n

Wysocki, V. H.; Burinsky, D. J.; Cooks, R. G., Competitive dehydration and deamination of \u03b1,\u03c9-amino alcohols and \u03b1,\u03c9-amino acids in the gas phase. J. Org. Chem. <\/em>1985,<\/strong> 50<\/em> (8), 1287-91.\u00a0[Request reprint\u00a0\u00a9<\/sup>\u00a0(pdf)]<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Most Recent Publications First Wang, Q.; Wang, Q.; Qi, Z.; Moeller, W.; Wysocki, V.H.; Sun, L. “Native Proteomics by Capillary Zone Electrophoresis-Mass Spectrometry.” Angewandte Chemie. 2024, Volume136,\u00a0Issue48. DOI: 10.1002\/ange.202408370. [Request reprint \u00a9 (pdf)] Shaw, J. B.; Harvey, S. R.; Du, C.; Xu, Z.; Edgington, R. M.; Olmedillas, E.; Saphire, E. O.; Wysocki, V. H. Protein … Continue reading “Publications”<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":4,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-78","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/research.cbc.osu.edu\/wysocki.11\/wp-json\/wp\/v2\/pages\/78","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/research.cbc.osu.edu\/wysocki.11\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/research.cbc.osu.edu\/wysocki.11\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/research.cbc.osu.edu\/wysocki.11\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/research.cbc.osu.edu\/wysocki.11\/wp-json\/wp\/v2\/comments?post=78"}],"version-history":[{"count":335,"href":"https:\/\/research.cbc.osu.edu\/wysocki.11\/wp-json\/wp\/v2\/pages\/78\/revisions"}],"predecessor-version":[{"id":2677,"href":"https:\/\/research.cbc.osu.edu\/wysocki.11\/wp-json\/wp\/v2\/pages\/78\/revisions\/2677"}],"up":[{"embeddable":true,"href":"https:\/\/research.cbc.osu.edu\/wysocki.11\/wp-json\/wp\/v2\/pages\/4"}],"wp:attachment":[{"href":"https:\/\/research.cbc.osu.edu\/wysocki.11\/wp-json\/wp\/v2\/media?parent=78"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}