Publications

(Updated as of November 4th, 2024)

2024

86) Sekera, E. R.; Rosas, L.; Holbrook, J. H.; Angeles-Lopez, Q. D.; Khaliullin, T.; Rojas, M.; Mora, A. L.; Hummon, A. B. “Single Cell MALDI-MSI Analysis of Lipids and Proteins within a Replicative Senescence Fibroblast Model.” Journal of the American Society for Mass Spectrometry. 2024. doi/10.1021/jasms.4c00095.

85) Mukherjee, S.; Kulkarni, A.; Holbrook, J. H.; Dasanayake, G. S.; Hu, D.; Tanner, E. E. L.; Hummon, A. B.; Watkins, D. L. “Uptake of Self-Assembling Amphiphilic Tryptophan-Based Polymer Nanoparticles in Three-Dimensional Cell Culture Models.” ACS Applied Nano Materials. 2024. doi/10.1021/acsanm.4c04589.

84) Lopez, A.; Holbrook, J. H.; Kemper, G. E.; Lukowski, J. K.; Andrews, W. T.; Hummon, A. B. “Tracking Drugs and Lipids: Quantitative Mass Spectrometry Imaging of Liposomal Doxorubicin Delivery and Bilayer Fate in Three-Dimensional Tumor Models.” Analytical Chemistry. 2024. doi: 10.1021/acs.analchem.4c01586.

83)Sekera, E. R.; Akkaya-Colak, K.; Lopez, A.; Mihaylova, M.; Hummon, A. B. “Mass Spectrometry Imaging and Histology for the Analysis of Budding Intestinal Organoids.” Analytical Chemistry. 2024. doi: 10.1021/acs.analchem.3c05725.

82) Shannon, A.; Boos, C.; Searle, B.; Hummon, A. B. “Gas-phase Fractionation Data-Independent Acquisition analysis of 3D Cocultured Spheroid Tumor Model Reveals Altered Translational Processes and Signaling using Proteomics.” Journal of Proteome Research. 2024. doi: 10.1021/acs.jproteome.3c00786.

81) Holbrook, J. H.; Kemper, G.; Hummon, A. B. “Quantitative Mass Spectrometry Imaging: Therapeutics & Biomolecules.” Chemical Communications. 2024. doi: 10.1039/D3CC05988J.

2023

80) Fries, B. D.; Tobias, F.; Wang, Y.; Holbrook, J. H.; Hummon, A. B. “Lipodomics Profiling Reveals Differential Alterations after FAS Inhibition in Colon Cancer Cell Culture Models.” Journal of Proteome Research. 2023. doi: 10.1021/10.1021/acs.jproteome.3c00593.

79) Chua, A. E.; Pfeifer, L. D.; Sekera, E. R.; Hummon, A. B.; Desaire H. “Workflow for Evaluating Normalization Tools for Omics Data Using Supervised and Unsupervised Machine Learning.” Journal of the American Society for Mass Spectrometry. 2023. doi: 10.1021/10.1021/jasms.3c00295.

78) Beller, N. C.; Wang, Y.; Hummon, A. B. “Evaluating the Pharmacokinetics and Pharmacodynamics of Chemotherapeutics within a Spatial SILAC-Labeled Spheroid Model System.” Anal. Chem. 2023. doi: 10.1021/acs.analchem.3c00905.

77) Holbrook, J. H.; Sekera, E. R.; Lopez, A.; Fries, B. D.; Tobias, F.; Akkaya, K.; Mihaylova, M. M.; Hummon, A. B. “Enhancement of Lipid Signals in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry with Ammonium Fluoride a Matrix Additive.” Anal. Chem. 2023. doi: 10.1021/acs.analchem.3c00753.

76) Li, Y., et al. “Targeting a xenobiotic transporter to ameliorate vincristine-induced sensory neuropathy.” JCI Insight. 2023. doi: 10.1172/jci.insight.164646.

75) Badjic, J. D.; Gunawardana, V. W. L.; Ward, C.; Wang, H.; Holbrook, J. H.; Sekera, E. R.; Cui, H.; Hummon, A. B. “Crystalline Nanoparticles of Water-Soluble Covalent Basket Cages (CBCs) for Encapsulation of Anticancer Drugs” Angewandte Chemie International Edition. 2023. doi: 10.1002/anie.202306722.

74) Wang, Y.; Hummon, A. B. “Quantification of Irinotecan in Single Spheroids Using Internal Standards by MALDI Mass Spectrometry Imaging” Analytical Chemistry. 2023. doi: 10.1021/acs.analchem.3c00699.

73) Shortt, R. L.; Wang, Y.; Hummon, A. B.; Jones, L. M. “Development of Spheroid-FPOP: An In-Cell Protein Footprinting Method for 3D Tumor Spheroids” Journal of the American Society for Mass Spectrometry. 2023. doi: 10.1021/jasms.2c00307.

72) Zhou, Q.; Alvarez, M.R.S.; Solakyildirim, K.; Tena, J.; Serrano, L.M.N.; Lam, M.;  Nguyen, C.; Tobias, F.; Hummon, A.B.; Nacario, R.C.; Lebrilla, C.B. “Multi-Glycomic analysis of spheroid glycocalyx differentiates 2- and 3-dimensional cell models” Glycobiology. 2022. doi: 10.1093/glycob/cwac075.

2022

71) Hempfling, Jordan; Sekera, Emily; Sarkar, Amar; Hummon, Amanda; Pei, Dehua. “Generation of Proteins with Free N-Terminal Cysteine by Aminopeptidases” Journal of the American Chemical Society. 2022. doi: 10.1021/jacs.2c10194.

70) McCool, E. N.; Xu, T.; Chen, W.; Beller, N. C.; Nolan, S. M.; Hummon, A. B.; Liu, X.; Sun, L. “Deep top-down proteomics revealed significant proteoform-level differences between metastatic and nonmetastatic colorectal cancer cells” Science Advances. 2022. doi: 10.1093/glycob/cwac075.

69) Tobias, F.; Hummon, A.B. “Lipidomic Comparison of 2D and 3D Colon Cancer Cell Culture Models” Journal of Mass Spectrometry. 2022. 57(8): :e4880. doi: 10.1002/jms.4880. PMID: 36028991.

68) Beller, N.C.; Hummon, A.B. “Advances in stable isotope labeling: dynamic labeling for spatial and temporal proteomic analysis” Mol Omics. 2022. doi: 10.1039/d2mo00077f.

2021

67) Beller, NC; Lukowski, JK; Ludwig, KR; Hummon, AB “Spatial SILAC Isotopic Labeling by Amino Acids in Cell Culture: Pulse Chase Labeling of Three-Dimensional Multicellular Spheroids for Global Proteome Analysis” Analytical Chemistry. 2021 Dec 7; 93(48):15990-15999.  doi: 10.1021/acs.analchem.1c03461.

66) Wang, Y; Hummon, AB “MS imaging of multicellular tumor spheroids and organoids as an emerging tool for personalized medicine and drug discovery” J Biol Chem. 2021 Oct; 297(4): 101139.  doi: 10.1016/j.jbc.2021.101139.

65). Andrews, WT; Bickner, AN; Tobias, F; Ryan, KA; Bruening, ML; Hummon, AB “Electroblotting through enzymatic membranes to enhance molecular tissue imaging” J Am Soc Mass Spectrom. 2021 Jul 7;32(7):1689-1699. doi: 10.1021/jasms.1c00046. Epub 2021 Jun 10.

64). Shannon, AE; Boos, CE; Hummon AB “Co-culturing multicellular tumor models: Modeling the tumor microenvironment and analysis techniques” Proteomics. 2021 Feb 10:e2000103. doi: 10.1002/pmic.202000103. Epub ahead of print. PMID: 33569922.

63). Bibyk, MJ; Campbell, MJ; Hummon AB “Mass spectrometric investigations of caloric restriction mimetics” Proteomics. 2021 Jan 18:e2000121. doi: 10.1002/pmic.202000121. PMID: 33460282.

2020

62). Lindhorst, PH; Hummon, AB “Proteomics of Colorectal Cancer: Tumors, Organoids, and Cell Cultures-A Minireview” Front Mol Biosci 2020 Dec 10.  PMID: 33363210

61). Dougherty, PG; Wellmerling, JH; Koley, A; Lukowski, JK; Hummon, AB; Cormet-Boyaka, E; Pei, D “Cyclic Peptidyl Inhibitors against CAL/CFTR Interaction for Treatment of Cystic Fibrosis” J Med Chem 2020 Dec 24;63(24):15773-15784. PMID: 33314931

60). Dougherty, PG, Karpurapu, M; Koley, A; Lukowski, JK; Qian, Z; Nirujogi, TS; Rusu, L; Chung, S; Hummon, AB; Li, HW; Christman, JW; Pei, D “A Peptidyl Inhibitor that Blocks Calcineurin-NFAT Interaction and Prevents” Acute Lung Injury J Med Chem 2020 Nov 12;63(21):12853-12872. PMID: 33073986

59). Bickner, AN; Champion, MM; Hummon, AB; Bruening, ML “Electroblotting through a tryptic membrane for LC-MS/MS analysis of proteins separated in electrophoretic gels” Analyst 2020 Nov 23;145(23):7724-7735. PMID: 33000802

58). Tobias, F and Hummon AB “Considerations for MALDI-based Quantitative Mass Spectrometry Imaging Studies” J Proteome Res. 2020 19 (9), 3620-3630. PMID: 32786684

57). Hua, D; Liu, X; Go, EP; Wang, Y; Hummon, AB; Desaire, H “How to Apply Supervised Machine Learning Tools to MS Imaging Files: Case Study with Cancer Spheroids Undergoing Treatment with the Monoclonal Antibody Cetuximab” J Am Soc Mass Spectrom 2020 Jul 1;31(7):1350-1357. PMID: 32469221

56). Buechler, SA; Stephens, MT; Hummon, AB; Ludwig, K; Cannon, E; Carter, TTC; Resnick, J; Gökmen-Polar, Y; and Badve, SS. “ColoType: a forty gene signature for consensus molecular subtyping of colorectal cancer tumors using whole-genome assay or targeted RNA-sequencing”. Sci Rep (10), 12123 2020. PMID: 32694712

55). Andrews, WT; Donahue, D; Holmes, A; Balsara, R; Castellino, FJ “In situ metabolite and lipid analysis of GluN2D-/- and wild-type mice after ischemic stroke using MALDI MSI” Anal Bioanal Chem. 2020 Feb 28. PMID: 32107573

2019

54). Tobias, F, McIntosh, JC, LaBonia, GJ, Boyce, MW, Lockett, MR, and Hummon, AB “Developing a Drug Screening Platform: MALDI-Mass Spectrometry Imaging of Paper-Based Cultures” Anal Chem. 2019, 91(24): 15370–15376. PMID: 31755703

53). Lukowski, JK and Hummon AB “Quantitative evaluation of liposomal doxorubicin and its metabolites in spheroids.” Anal Bioanal Chem. 2019 411(27): 7087-7094. PMID: 31471684

52). Wangsa, D; Braun, R; Stuelten, CH; Brown, M; Bauer, KM; Emons, G; Weston, LA; Hu, Y; Yang, HH; Lee, MP; Bauer, P; Warner, L; Upender, M; Hummon, AB; Camps, J; Ried, T “Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells” Neoplasia. 2019 21(7): 721-729. PMID: 31174021

51). Chen, D; Ludwig, KR; Yang, Z. Shen, X; Hummon, AB; Sun, L “Capillary zone electrophoresis-tandem mass spectrometry for large-scale phosphoproteomics with the production of over 11000 phosphopeptides from the colon carcinoma HCT116 cell line” Anal Chem. 2019 91(3): 2201–2208. PMID: 30624053

2018

50). Liu, X; Lukowski, JK; Flinders, C; Mumenthaler, S; Hummon, AB “MALDI-MSI of Immunotherapy: Mapping the EGFR-Targeting Antibody Cetuximab in 3D Colon Cancer Cell Cultures” Anal Chem. 2018 90(24): 14156-64. PMID: 30479121

49). Shields, PG; Song, MA; Freudenheim, JL; Brasky, TM; Mathe, E; McElroy, JP; Hummon, AB; Wewers, MD “Electronic Cigarettes and the Lung Proteome.” Am J Respir Crit Care Med. 2018 198(10):1350-1. PMID: 30153045

48).  Schroll MM and Hummon AB “Employing proteomics to understand the effects of nutritional intervention in cancer treatment.” Anal Bioanal Chem 2018 Oct;410(25):6371-6386. PMID: 29974151

47).  Schroll MM, Ludwig KR, LaBonia GJ, Herring EL, Hummon AB. “Combined Short-Term Glucose Starvation and Chemotherapy in 3D Colorectal Cancer Cell Culture Decreases 14-3-3 Family Protein Expression and Phenotypic Response to Therapy.”J Am Soc Mass Spectrom 2018 29(10): 2012-2022. PMID: 30019162

46).  Ludwig KR, Schroll MM, Hummon AB. “Comparison of In-Solution, FASP, and S-Trap Based Digestion Methods for Bottom-Up Proteomic Studies.” J Proteome Res.2018 Jul 6;17(7):2480-2490

45). Schroll MM, Ludwig KR, Bauer KM, Hummon AB. “Calcitriol Supplementation Causes Decreases in Tumorigenic Proteins and Different Proteomic and Metabolomic Signatures in Right versus Left-Sided Colon Cancer.” Metabolites. 2018 Jan 11;8(1):5. PMID: 29324674

44). Feist PE, Loughran EA, Stack MS, Hummon AB. “Quantitative proteomic analysis of murine white adipose tissue for peritoneal cancer metastasis.” Anal Bioanal Chem. 2018 Feb;410(5):1583-1594. PMID: 29282499

43). LaBonia GJ, Ludwig KR, Mousseau CB, Hummon AB. “iTRAQ Quantitative Proteomic Profiling and MALDI-MSI of Colon Cancer Spheroids Treated with Combination Chemotherapies in a 3D Printed Fluidic Device.” Anal Chem. 2018 Jan 16;90(2):1423-1430. PMID: 29227110

42). Liu X, Flinders C, Mumenthaler SM, Hummon AB. “MALDI Mass Spectrometry Imaging for Evaluation of Therapeutics in Colorectal Tumor Organoids.” J Am Soc Mass Spectrom. 2018 Mar;29(3):516-526. PMID: 29209911

2017

41). Andrews WT, Skube SB, Hummon AB. “Magnetic bead-based peptide extraction methodology for tissue imaging.” Analyst. 2017 Dec 18;143(1):133-140

40). Bailey KA, Klymenko Y, Feist PE, Hummon AB, Stack MS, Schultz ZD. “Chemical Analysis of Morphological Changes in Lysophosphatidic Acid-Treated Ovarian Cancer Cells.” Sci Rep. 2017 Nov 10;7(1):15295

39).  Zhang G, Vilim FS, Liu DD, Romanova EV, Yu K, Yuan WD, Xiao H, Hummon AB, Chen TT, Alexeeva V, Yin SY, Chen SA, Cropper EC, Sweedler JV, Weiss KR, Jing J. “Discovery of leucokinin-like neuropeptides that modulate a specific parameter of feeding motor programs in the molluscan model, Aplysia.” J Biol Chem. 2017 Nov 17;292(46):18775-18789

38). Lukowski JK, Weaver EM, Hummon AB. “Analyzing Liposomal Drug Delivery Systems in Three-Dimensional Cell Culture Models Using MALDI Imaging Mass Spectrometry”. Analytical Chemistry. 2017. In Press.

37). Boyce MW, LaBonia GJ, Hummon AB, Lockett MR. “Assessing chemotherapeutic effectiveness using a paper-based tumor model”. Analyst. 2017. In Press.

36). Schroll MM, LaBonia GJ, Ludwig KR, Hummon AB. “Glucose restriction combined with autophagy inhibition and chemotherapy in HCT 116 spheroids decreases cell clonogenicity and viability regulated by tumor supressor genes”. JPR. 2017. In Press.

35). Feist P, Sidoli S, Liu X, Schroll M, Rahmy S, Fujiwara R, Garcia B, Hummon AB. “Multicellular Tumor Spheroids Combined with Mass Spectrometric Histone Analysis to Evaluate Epigenetic Drugs” . Analytical Chemistry. 2017. Mar 7;89(5):2773-2781.

34). Ludwig KR, Hummon AB. “Mass Spectrometry for the Discovery of Biomarkers for Sepsis”. Molecular Biosystems. 2017. Mar 28;13(4):648-664.

2016

33). US Patent #9,464,328. “Biomarkers and Uses Thereof in Prognosis and Treatment Strategies for Right-Side Colon Cancer Disease and Left-Side Colon Cancer Disease” (Co-Inventor Steven Buechler).

32). Schunter A, Yue XS, Hummon AB. “Phosphoproteomics of Colon Cancer Metastasis: Comparative Mass Spectrometric Analysis of the Isogenic Primary and Metastatic Cell Lines SW480 and SW620”. Analytical and Bioanalytical Chemistry. 2016. Mar;409(7):1749-1763.

31). Liu X, Hummon AB.”Chemical Imaging of Platinum-Based Drugs and their Metabolites“. Scientific Reports. 2016. Dec 5;6:38507.

30). Yue XS, Lukowski JK, Weaver EM, Skube SB, Hummon AB. ”Quantitative Proteomic and Phosphoproteomic Comparison of 2D and 3D Colon Cancer Cell Culture Models”. Journal of Proteome Research. 2016. Dec 2;15(12):4265-4276..

29). Schroll M, Liu X, Herzog S, Skube SB, Hummon AB. “Nutrient Restriction of Glucose or Serum Results in Similar Proteomic Expression Changes in 3D Colon Cancer Cell Cultures” Nutrition Research. 2016. Oct;36(10):1068-1080.

28) . Amanda B Hummon. “Toward Integrated Omics”. The Analytical Scientist, Issue 0616. 2016.

27). LaBonia GJ, Lockwood SY, Heller AA, Spence DM, Hummon AB. “Drug penetration and metabolism in 3-dimensional cell cultures treated in a 3D printed fluidic device: Assessment of irinotecan via MALDI imaging mass spectrometry”. Proteomics. 2016. Jun;16(11-12):1814-21.

26). Ludwig KR, Dahl R, Hummon AB. “Evaluation of the mirn23a Cluster through an iTRAQ-based Quantitative Proteomic Approach”. Journal of Proteome Research. 2016. May 6; 15(5):1497-505.

2015

25). Ludwig KR, Sun L, Zhu G, Dovichi NJ, Hummon AB. “Over 2,300 Phosphorylated Peptide Identifications with Single-Shot Capillary Zone Electrophoresis-Tandem Mass Spectrometry in a 100 min Separation”. Analytical Chemistry. 2015. Sept 23; 87(19): 9532-9537.

24). Yue XS, Schunter A, Hummon AB. “Comparing Multi-Step IMAC and Multi-Step TiO2 Methods for Phosphopeptide Enrichment”. Analytical Chemistry. 2015. August 3;87(17):8837-8844.

23). Liu X, Hummon AB. “Mass Spectrometry Imaging of Therapeutics from Animal Models to Three-Dimensional Cell Cultures”. Analytical Chemistry. 2015. Jun 18;87(19):9508-9519.

22). Weaver EM, Hummon AB, Keithley RB. “Chemometric Analysis of MALDI Mass Spectrometric Images of Three-Dimensional Cell Culture Systems”. Analytical Methods. 2015. Sept 7;7(17):7208-7219.

21). Feist P, and Hummon AB “Proteomic Challenges: Sample Preparation Techniques for Microgram-Quantity Protein Analysis from Biological Samples”. International Journal of Molecular Sciences. 2015. Feb 5;16(2):3537-63.

20). Feist P, Sun L, Liu X, Dovichi NJ, Hummon AB. “Bottom-up proteomic analysis of single HCT 116 colon carcinoma multicellular spheroids“. Rapid Communications in Mass Spectrometry. 2015. Apr 15;29(7):654-658.

2014

19). Liu X, Hummon AB. “Quantitative Determination of Irinotecan and the Metabolite SN-38 by nLC-ESI-MS/MS in Different Regions of Multicellular Tumor Spheroids“. Journal of The American Society for Spectrometry. 2014. Apr; 26(4):577-86.

18). Bauer KM, Watts T, Buechler S, Hummon AB. “Proteomic and functional investigation of the colon cancer relapse-associated genes NOX4 and ITGA3“. Journal of Proteome Research. 2014 Nov 7; 13 (11);4910-8.

17). Ahlf DR, Masyuko RN, Hummon AB, Bohn PW. “Correlated Mass Spectrometry Imaging and Confocal Raman Microscopy for Studies of Three-Dimensional Cell Culture Sections”. Analyst. 2014 Sep 21;139 (18);4578-85.

16). Wheatcraft Ahlf DR, Liu X, Hummon AB. “Sample Preparation Strategies for Mass Spectrometry Imaging of 3D Cell Culture Models”. Journal of Visualized Experiments. 2014 Dec 5;(94).

2013

15). Weston LA, Bauer KM, Skube SB, Hummon AB. “Selective, bead-based global peptide capture using a bifunctional crosslinker”. Anal Chem. 2013 Nov 19;85(22):10675-9.

14). Weston LA, Hummon AB. “Comparative LC-MS/MS analysis of Optimal Cutting Temperature (OCT) compound removal for the study of mammalian proteomes“. Analyst. 2013 Nov 7;138(21):6380-4.

13). Keithley R.B., Weaver E.M., Metzinger M.P., Rosado A.M., Hummon A.B., Dovichi N.J. “Single Cell Metabolic Profiling of Tumor Mimics.” Anal Chem. 2013 Oct 1;85(19);8910-8.

12). Yue XS, Hummon A.B. “Combination of Multi-Step IMAC Enrichment with High-pH Reverse Phase Separation for In-Depth Phosphoproteomic Profiling“. Journal of Proteome Research. 2013 Sep 6;12(9):4176-86.

11). Weston LA*, Bauer KM*, Hummon A.B. “Comparison of bottom-up proteomic approaches for LC-MS analysis of complex proteomes“. Analytical Methods, 2013, 5 (18), 4615 – 4621.

10). Liu, X, Weaver EM, Hummon A.B.”Evaluation of Therapeutics in Three-Dimensional Cell Culture Systems by MALDI Imaging Mass Spectrometry“. Analytical Chemistry, 2013 Jul 2;85(13):6295-302. Epub 2013 Jun 11.

9). Hummon, A.B.; Dovichi, N.J. “The Tools of Proteomics” The Analytical Scientist, 2013, 1, 413-420.

8). Dovichi NJ, Hummon A.B. “The Tools Behind Genomics” The Analytical Scientist, 2013, 1, 24-31.

7). Weaver EM, Hummon A.B. “Imaging mass spectrometry: from tissue sections to cell cultures” Advanced Drug Discovery Reviews, 2013 Jul;65(8):1039-55.

2012

6). Yue XS, Hummon A.B. “Mass spectrometry-based phosphoproteomics in cancer research.” Front. Biol. 2012, 7(6): 566–586.

5). Bauer KM, Hummon A.B. “Effects of the miR-143/-145 MicroRNA Cluster on the Colon Cancer Proteome and Transcriptome.” J Proteome Res. 2012 Sep 7;11(9):4744-54.

4). Bauer KM, Lambert PA, and Hummon A.B. “Comparative label-free LC-MS/MS analysis of colorectal adenocarcinoma and metastatic cells treated with 5-fluorouracil” Proteomics 2012 Jun;12(12):1928-37.

3). Hummon AB, Pitt JJ, Camps J, Emons G, Skube SB, Huppi K, Jones TL, Beissbarth T, Kramer F, Grade M, Difilippantonio MJ, Ried T and Caplen NJ. “Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.” Molecular Cancer 2012 Jan 4;11:1.

2). Bauer, K.M.; Hummon, A.B.; Buechler, S. “Right-side and left-side colon cancer follow different pathways to relapse.” Mol Carcinog., 2012 May; 51(5);411-21.

2011

1). Li H, Hummon A.B. “Imaging mass spectrometry of three-dimensional cell culture systems.” Anal Chem. 2011 Nov 15;83(22) 8794-801.

Post Doc and Graduate Training

18). Padilla-Nash HM, McNeil NE, Yi M, Nguyen QT, Hu Y, Wangsa D, Mack DL, Hummon AB, Case C, Cardin E, Stephens R, Difilippantonio MJ, Ried T. Aneuploidy, Oncogene Amplification, and Epithelial to Mesenchymal Transition Define Spontaneous Transformation of Murine Epithelial Cells.”Carcinogenesis. 2013 Mar 15;73(6);2013-13.

17). Camps J, Pitt JJ, Emons G, Hummon AB, Case CM, Grade M, Jones TL, Nguyen QT, Ghadimi BM, Beissbarth T, Difilippantonio MJ, Caplen NJ, Ried T. ”Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer.” Cancer Res. 2013 Mar 15;73(6):2003-13.

16). Grade, M.; Hummon, A.B.; Emons, G.; Camps, J.; Spitzner, M.; Hoermann, P.; Gaedcke, J.; Ebner, R.; Becker, H.; Ghadimi, B.M.; Beissbarth, T.; Difilippantonio, M.J.; Caplen, N.J.; Ried, T. “Identification and Validation of NOL5A and RPS2 as Potential Therapeutic Targets in Colorectal Cancer using a Functional Genomics Approach.” Int J. Cancer. March 2011 128(5):1069-79.

15). Camps, J.; Nguyen, Q.T.; Padilla-Nash, H.M.; Knutsen, T.; McNeil, N.E.; Wangsa, D.; Hummon, A.B.; Grade, M.; Ried, T.; Difilippantonio, M.J. “Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer.” Genes Chromosomes Cancer. 2009 Nov;48(11);1002-17.

14). Camps, J.; Grade, M.; Nguyen, Q.T.; Hörmann, P.; Becker, S.; Hummon, A.B.; Rodriguez, V.; Chandrasekharappa, S.; Chen, Y.; Difilippantonio, M.J.; Becker, H.; Ghadimi, B.M.; Ried, T. “Chromosome breakpoints in primary colon cancer cluster at sites of structural variants in the genome.” Cancer Res. 2008 Mar 1;68(5):1284-95.

13). Hummon, A.B.; Martin, S.E.; Caplen, N.J. “RNAi screens: Going right to the target.” Screening-Trends in Drug Discovery 4, 2 (2007).

12). Hummon, A.B.; Lim, S.R.; Difilippantonio, M.J.; Ried, T. “Isolation and solubilization of proteins after TRIzol extraction of RNA and DNA from patient material following prolonged storage.” Biotechniques 42, 467 (2007).

11). Grade, M.; Hörmann, P.; Becker, S.; Hummon, A.B.; Wangsa, D.; Varma, S.; Simon, R.; Liersch, T.; Becker, H.; Difilippantonio, M.J.; Ghadimi, B.M.; Ried, T. “Gene Expression Profiling Reveals a Massive, Aneuploidy-Dependent Transcriptional Deregulation and Distinct Differences between Lymph Node Negative and Positive Colon Carcinomas.” Cancer Res. 67, 41 (2007).

10). Hummon, A.B.; Richmond, T.A.; Amare, A.; Ewing, M.A.; Verleyen, P.; Baggerman, G.; Schoofs, L.; Southey, B.; Rodriguez-Zas, S.L.; Robinson, G.E.; Sweedler, J.V. “From the Genome to the Proteome: Uncovering Peptides in the Apis Brain.” Science 314, 647 (2006).

9). The Honeybee Genome Sequencing Consortium. “Insights into social insects from the genome of the honeybee Apis mellifera.” Nature 443, 931 (2006).

8). Amare, A.; Hummon, A.B.; Southey, B.R.; Zimmerman, T.A.; Rodriguez-Zas, S.L.; Sweedler, J.V. “Bridging Neuropeptidomics and Genomics with Bioinformatics: Prediction of Mammalian Neuropeptide Prohormone Processing.” J. Proteome Res. 5, 1162 (2006).

7). Hummon, A.B.; Amare, A.; Sweedler, J.V. “Discovering New Invertebrate Neuropeptides using Mass Spectrometry.” Mass Spectrom. Rev. 25, 77 (2006).

6). Stuart, J.N.; Hummon, A.B.; Sweedler, J.V. “The Chemistry of Thought: Neurotransmitters in the Brain.” Anal. Chem. 76, 121A (2004).

5). Cummins, S.F.; Nichols, A.; Amare, A.; Hummon, A.B.; Sweedler, J.V.; Nagle, G.T. “Novel Candidate Protein Pheromones in Aplysia: Identification, Characterization, Expression, and Biological Activity.” J. Biol. Chem. 279, 25614 (2004).

4). Page, J.S.; Hummon, A.B.; Sweedler, J.V. “Single Cell Peptide Analysis with MALDI-MS” for Encyclopedia of Mass Spectrometry. Vol 2, Biological Applications. Eds. R. Caprioli and M. Gross. 2004.

3). Hummon, A.B.; Hummon, N.P.; Corbin, R.W.; Li, L.; Vilim, F.S.; Weiss, K.R.; Sweedler, J.V. “From Precursor to Final Peptides: A Statistical Sequence-Based Approach to Predicting Prohormone Processing.” J. Proteome Res. 2, 650 (2003).

2). Hummon, A.B.; Corbin, R.W.; Sweedler, J.V. “Discovering New Neuropeptides using Single Cell Mass Spectrometry.” Trends Anal. Chem. 22, 515 (2003).

1). Hummon, A.B.; Huang, H.; Kelley, W.P.; Sweedler. J.V. “A Novel Prohormone Processing Site in Aplysia californica: the Leu-Leu Rule.” J. Neurochem. 82, 1398 (2002).