Publications

Musier-Forsyth Publications

  1. Musier-Forsyth, K, Rein, A, Freed, EO. Tribute to Dr. Judith G. Levin (1934-2023). Viruses. 2024;16 (2):. doi: 10.3390/v16020178. PubMed PMID:38399955 PubMed Central PMC10893463.
  2. Joshi, J, McCauley, MJ, Morse, M, Muccio, MR, Kanlong, JG, Rocha, MS et al.. Mechanism of DNA Intercalation by Chloroquine Provides Insights into Toxicity. Int J Mol Sci. 2024;25 (3):. doi: 10.3390/ijms25031410. PubMed PMID:38338688 PubMed Central PMC10855526.
  3. Tang, Y, Behrens, RT, St Gelais, C, Wu, S, Vivekanandan, S, Razin, E et al.. Human lysyl-tRNA synthetase phosphorylation promotes HIV-1 proviral DNA transcription. Nucleic Acids Res. 2023;51 (22):12111-12123. doi: 10.1093/nar/gkad941. PubMed PMID:37933844 PubMed Central PMC10711549.
  4. Gopalan, V, Musier-Forsyth, K. Transfer RNAs: A treasure trove that keeps on giving. J Biol Chem. 2023;299 (10):105170. doi: 10.1016/j.jbc.2023.105170. PubMed PMID:37769358 PubMed Central PMC10539951.
  5. Smith, S, Seth, J, Midkiff, A, Stahl, R, Syu, YC, Shkriabai, N et al.. The Pleiotropic Effects of YBX1 on HTLV-1 Transcription. Int J Mol Sci. 2023;24 (17):. doi: 10.3390/ijms241713119. PubMed PMID:37685922 PubMed Central PMC10487795.
  6. Pino, MG, Rich, KA, Hall, NJ, Jones, ML, Fox, A, Musier-Forsyth, K et al.. Heterogeneous splicing patterns resulting from KIF5A variants associated with amyotrophic lateral sclerosis. Hum Mol Genet. 2023;32 (22):3166-3180. doi: 10.1093/hmg/ddad134. PubMed PMID:37593923 .
  7. Levin, JG, Musier-Forsyth, K, Rein, A. Molecular Genetics of Retrovirus Replication. Viruses. 2023;15 (7):. doi: 10.3390/v15071549. PubMed PMID:37515235 PubMed Central PMC10385656.
  8. Nikolaitchik, OA, Islam, S, Kitzrow, JP, Duchon, A, Cheng, Z, Liu, Y et al.. HIV-1 usurps transcription start site heterogeneity of host RNA polymerase II to maximize replication fitness. Proc Natl Acad Sci U S A. 2023;120 (23):e2305103120. doi: 10.1073/pnas.2305103120. PubMed PMID:37252967 PubMed Central PMC10266039.
  9. Ma, X, Bakhtina, M, Shulgina, I, Cantara, WA, Kuzmishin Nagy, AB, Goto, Y et al.. Structural basis of tRNAPro acceptor stem recognition by a bacterial trans-editing domain. Nucleic Acids Res. 2023;51 (8):3988-3999. doi: 10.1093/nar/gkad192. PubMed PMID:36951109 PubMed Central PMC10164551.
  10. Jin, D, Zhu, Y, Schubert, HL, Goff, SP, Musier-Forsyth, K. HIV-1 Gag Binds the Multi-Aminoacyl-tRNA Synthetase Complex via the EPRS Subunit. Viruses. 2023;15 (2):. doi: 10.3390/v15020474. PubMed PMID:36851687 PubMed Central PMC9967848.
  11. Jin, D, Wek, SA, Cordova, RA, Wek, RC, Lacombe, D, Michaud, V et al.. Aminoacylation-defective bi-allelic mutations in human EPRS1 associated with psychomotor developmental delay, epilepsy, and deafness. Clin Genet. 2023;103 (3):358-363. doi: 10.1111/cge.14269. PubMed PMID:36411955 PubMed Central PMC9898101.
  12. Cantara, WA, Pathirage, C, Hatterschide, J, Olson, ED, Musier-Forsyth, K. Phosphomimetic S207D Lysyl-tRNA Synthetase Binds HIV-1 5'UTR in an Open Conformation and Increases RNA Dynamics. Viruses. 2022;14 (7):. doi: 10.3390/v14071556. PubMed PMID:35891536 PubMed Central PMC9315659.
  13. Byun, JK, Vu, JA, He, SL, Jang, JC, Musier-Forsyth, K. Plant-exclusive domain of trans-editing enzyme ProXp-ala confers dimerization and enhanced tRNA binding. J Biol Chem. 2022;298 (9):102255. doi: 10.1016/j.jbc.2022.102255. PubMed PMID:35835222 PubMed Central PMC9425024.
  14. Lang, S, Ibba, M, Musier-Forsyth, K. New paradigm for teaching scientific writing in STEM. Trends Biochem Sci. 2022;47 (8):631-634. doi: 10.1016/j.tibs.2022.03.019. PubMed PMID:35466035 .
  15. Gien, H, Morse, M, McCauley, MJ, Kitzrow, JP, Musier-Forsyth, K, Gorelick, RJ et al.. HIV-1 Nucleocapsid Protein Binds Double-Stranded DNA in Multiple Modes to Regulate Compaction and Capsid Uncoating. Viruses. 2022;14 (2):. doi: 10.3390/v14020235. PubMed PMID:35215829 PubMed Central PMC8879225.
  16. Lomidze, L, Yang, M, Khutsishvili, D, Metreveli, N, Musier-Forsyth, K, Kankia, B et al.. Structure of Tetrahelical DNA Homopolymers Supports Quadruplex World Hypothesis. ACS Omega. 2022;7 (5):4311-4316. doi: 10.1021/acsomega.1c06026. PubMed PMID:35155924 PubMed Central PMC8829921.
  17. Boyle, EP, Lomidze, L, Musier-Forsyth, K, Kankia, B. A Chimeric DNA/RNA Antiparallel Quadruplex with Improved Stability. ChemistryOpen. 2022;11 (2):e202100276. doi: 10.1002/open.202100276. PubMed PMID:35103415 PubMed Central PMC8805387.
  18. Sumner, C, Kotani, O, Liu, S, Musier-Forsyth, K, Sato, H, Ono, A et al.. Molecular Determinants in tRNA D-arm Required for Inhibition of HIV-1 Gag Membrane Binding. J Mol Biol. 2022;434 (2):167390. doi: 10.1016/j.jmb.2021.167390. PubMed PMID:34883117 PubMed Central PMC8752508.
  19. Nikolaitchik, OA, Liu, S, Kitzrow, JP, Liu, Y, Rawson, JMO, Shakya, S et al.. Selective packaging of HIV-1 RNA genome is guided by the stability of 5' untranslated region polyA stem. Proc Natl Acad Sci U S A. 2021;118 (50):. doi: 10.1073/pnas.2114494118. PubMed PMID:34873042 PubMed Central PMC8685901.
  20. Liu, S, Koneru, PC, Li, W, Pathirage, C, Engelman, AN, Kvaratskhelia, M et al.. HIV-1 integrase binding to genomic RNA 5'-UTR induces local structural changes in vitro and in virio. Retrovirology. 2021;18 (1):37. doi: 10.1186/s12977-021-00582-0. PubMed PMID:34809662 PubMed Central PMC8609798.
  21. Jin, D, Wek, SA, Kudlapur, NT, Cantara, WA, Bakhtina, M, Wek, RC et al.. Disease-associated mutations in a bifunctional aminoacyl-tRNA synthetase gene elicit the integrated stress response. J Biol Chem. 2021;297 (4):101203. doi: 10.1016/j.jbc.2021.101203. PubMed PMID:34537243 PubMed Central PMC8511952.
  22. Dayeh, DM, Cantara, WA, Kitzrow, JP, Musier-Forsyth, K, Nakanishi, K. Correction to 'Argonaute-based programmable RNase as a tool for cleavage of highly-structured RNA'. Nucleic Acids Res. 2021;49 (16):9606. doi: 10.1093/nar/gkab742. PubMed PMID:34403465 PubMed Central PMC8450089.
  23. Hu, QH, Williams, MT, Shulgina, I, Fossum, CJ, Weeks, KM, Adams, LM et al.. Editing Domain Motions Preorganize the Synthetic Active Site of Prolyl-tRNA Synthetase. ACS Catal. 2020;10 (17):10229-10242. doi: 10.1021/acscatal.0c02381. PubMed PMID:34295570 PubMed Central PMC8293909.
  24. Harpster, C, Boyle, E, Musier-Forsyth, K, Kankia, B. HIV-1 genomic RNA U3 region forms a stable quadruplex-hairpin structure. Biophys Chem. 2021;272 :106567. doi: 10.1016/j.bpc.2021.106567. PubMed PMID:33713997 PubMed Central PMC8051326.
  25. Kankia, B. Quadruplex-Templated and Catalyzed Ligation of Nucleic Acids. Chembiochem. 2021;22 (7):1261-1267. doi: 10.1002/cbic.202000754. PubMed PMID:33217115 .
  26. Vargas-Rodriguez, O, Bakhtina, M, McGowan, D, Abid, J, Goto, Y, Suga, H et al.. Human trans-editing enzyme displays tRNA acceptor-stem specificity and relaxed amino acid selectivity. J Biol Chem. 2020;295 (48):16180-16190. doi: 10.1074/jbc.RA120.015981. PubMed PMID:33051185 PubMed Central PMC7705315.
  27. Sarni, S, Biswas, B, Liu, S, Olson, ED, Kitzrow, JP, Rein, A et al.. HIV-1 Gag protein with or without p6 specifically dimerizes on the viral RNA packaging signal. J Biol Chem. 2020;295 (42):14391-14401. doi: 10.1074/jbc.RA120.014835. PubMed PMID:32817318 PubMed Central PMC7573273.
  28. Liu, S, Refaei, M, Liu, S, Decker, A, Hinerman, JM, Herr, AB et al.. Hairpin RNA-induced conformational change of a eukaryotic-specific lysyl-tRNA synthetase extension and role of adjacent anticodon-binding domain. J Biol Chem. 2020;295 (34):12071-12085. doi: 10.1074/jbc.RA120.013852. PubMed PMID:32611767 PubMed Central PMC7443506.
  29. Liu, S, Kaddis Maldonado, R, Rye-McCurdy, T, Binkley, C, Bah, A, Chen, EC et al.. Rous Sarcoma Virus Genomic RNA Dimerization Capability In Vitro Is Not a Prerequisite for Viral Infectivity. Viruses. 2020;12 (5):. doi: 10.3390/v12050568. PubMed PMID:32455905 PubMed Central PMC7291142.
  30. Tuske, S, Zheng, J, Olson, ED, Ruiz, FX, Pascal, BD, Hoang, A et al.. Integrative structural biology studies of HIV-1 reverse transcriptase binding to a high-affinity DNA aptamer. Curr Res Struct Biol. 2020;2 :116-129. doi: 10.1016/j.crstbi.2020.06.002. PubMed PMID:33870216 PubMed Central PMC8052095.
  31. Kuzmishin Nagy, AB, Bakhtina, M, Musier-Forsyth, K. Trans-editing by aminoacyl-tRNA synthetase-like editing domains. Enzymes. 2020;48 :69-115. doi: 10.1016/bs.enz.2020.07.002. PubMed PMID:33837712 .
  32. Brigham, BS, Kitzrow, JP, Reyes, JC, Musier-Forsyth, K, Munro, JB. Intrinsic conformational dynamics of the HIV-1 genomic RNA 5'UTR. Proc Natl Acad Sci U S A. 2019;116 (21):10372-10381. doi: 10.1073/pnas.1902271116. PubMed PMID:31068467 PubMed Central PMC6534999.
  33. Musier-Forsyth, K. Aminoacyl-tRNA synthetases and tRNAs in human disease: an introduction to the JBC Reviews thematic series. J Biol Chem. 2019;294 (14):5292-5293. doi: 10.1074/jbc.REV119.007721. PubMed PMID:30799306 PubMed Central PMC6462500.
  34. Qualley, DF, Cooper, SE, Ross, JL, Olson, ED, Cantara, WA, Musier-Forsyth, K et al.. Solution Conformation of Bovine Leukemia Virus Gag Suggests an Elongated Structure. J Mol Biol. 2019;431 (6):1203-1216. doi: 10.1016/j.jmb.2019.01.036. PubMed PMID:30731090 PubMed Central PMC6424597.
  35. Jin, D, Musier-Forsyth, K. Role of host tRNAs and aminoacyl-tRNA synthetases in retroviral replication. J Biol Chem. 2019;294 (14):5352-5364. doi: 10.1074/jbc.REV118.002957. PubMed PMID:30700559 PubMed Central PMC6462514.
  36. Zhang, C, Cantara, W, Jeon, Y, Musier-Forsyth, K, Grigorieff, N, Lyumkis, D et al.. Analysis of discrete local variability and structural covariance in macromolecular assemblies using Cryo-EM and focused classification. Ultramicroscopy. 2019;203 :170-180. doi: 10.1016/j.ultramic.2018.11.016. PubMed PMID:30528101 PubMed Central PMC6476647.
  37. Lomidze, L, Williford, TH, Musier-Forsyth, K, Kankia, B. Isothermal amplification of long DNA segments by quadruplex priming amplification. Anal Methods. 2018;10 (25):2972-2979. doi: 10.1039/C8AY00843D. PubMed PMID:30505353 PubMed Central PMC6261523.
  38. Chen, L, Tanimoto, A, So, BR, Bakhtina, M, Magliery, TJ, Wysocki, VH et al.. Stoichiometry of triple-sieve tRNA editing complex ensures fidelity of aminoacyl-tRNA formation. Nucleic Acids Res. 2019;47 (2):929-940. doi: 10.1093/nar/gky1153. PubMed PMID:30418624 PubMed Central PMC6344894.
  39. Wu, W, Hatterschide, J, Syu, YC, Cantara, WA, Blower, RJ, Hanson, HM et al.. Human T-cell leukemia virus type 1 Gag domains have distinct RNA-binding specificities with implications for RNA packaging and dimerization. J Biol Chem. 2018;293 (42):16261-16276. doi: 10.1074/jbc.RA118.005531. PubMed PMID:30217825 PubMed Central PMC6200928.
  40. Dayeh, DM, Cantara, WA, Kitzrow, JP, Musier-Forsyth, K, Nakanishi, K. Argonaute-based programmable RNase as a tool for cleavage of highly-structured RNA. Nucleic Acids Res. 2018;46 (16):e98. doi: 10.1093/nar/gky496. PubMed PMID:29897478 PubMed Central PMC6144825.
  41. Antonucci, JM, Kim, SH, St Gelais, C, Bonifati, S, Li, TW, Buzovetsky, O et al.. SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4+ T Cells. J Virol. 2018;92 (15):. doi: 10.1128/JVI.00292-18. PubMed PMID:29793958 PubMed Central PMC6052313.
  42. Olson, ED, Musier-Forsyth, K. Retroviral Gag protein-RNA interactions: Implications for specific genomic RNA packaging and virion assembly. Semin Cell Dev Biol. 2019;86 :129-139. doi: 10.1016/j.semcdb.2018.03.015. PubMed PMID:29580971 PubMed Central PMC6167211.
  43. Song, Y, Zhou, H, Vo, MN, Shi, Y, Nawaz, MH, Vargas-Rodriguez, O et al.. Publisher Correction: Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid. Nat Commun. 2018;9 (1):1113. doi: 10.1038/s41467-018-03594-1. PubMed PMID:29535387 PubMed Central PMC5849694.
  44. Song, Y, Zhou, H, Vo, MN, Shi, Y, Nawaz, MH, Vargas-Rodriguez, O et al.. Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid. Nat Commun. 2017;8 (1):2281. doi: 10.1038/s41467-017-02201-z. PubMed PMID:29273753 PubMed Central PMC5741666.
  45. Comandur, R, Olson, ED, Musier-Forsyth, K. Conservation of tRNA mimicry in the 5'-untranslated region of distinct HIV-1 subtypes. RNA. 2017;23 (12):1850-1859. doi: 10.1261/rna.062182.117. PubMed PMID:28860303 PubMed Central PMC5689005.
  46. Duchon, AA, St Gelais, C, Titkemeier, N, Hatterschide, J, Wu, L, Musier-Forsyth, K et al.. HIV-1 Exploits a Dynamic Multi-aminoacyl-tRNA Synthetase Complex To Enhance Viral Replication. J Virol. 2017;91 (21):. doi: 10.1128/JVI.01240-17. PubMed PMID:28814526 PubMed Central PMC5640844.
  47. Danhart, EM, Bakhtina, M, Cantara, WA, Kuzmishin, AB, Ma, X, Sanford, BL et al.. Conformational and chemical selection by a trans-acting editing domain. Proc Natl Acad Sci U S A. 2017;114 (33):E6774-E6783. doi: 10.1073/pnas.1703925114. PubMed PMID:28768811 PubMed Central PMC5565427.
  48. Bacusmo, JM, Kuzmishin, AB, Cantara, WA, Goto, Y, Suga, H, Musier-Forsyth, K et al.. Quality control by trans-editing factor prevents global mistranslation of non-protein amino acid α-aminobutyrate. RNA Biol. 2018;15 (4-5):576-585. doi: 10.1080/15476286.2017.1353846. PubMed PMID:28737471 PubMed Central PMC6103672.
  49. Post, K, Olson, ED, Naufer, MN, Gorelick, RJ, Rouzina, I, Williams, MC et al.. Mechanistic differences between HIV-1 and SIV nucleocapsid proteins and cross-species HIV-1 genomic RNA recognition. Retrovirology. 2016;13 (1):89. doi: 10.1186/s12977-016-0322-5. PubMed PMID:28034301 PubMed Central PMC5198506.
  50. Todd, GC, Duchon, A, Inlora, J, Olson, ED, Musier-Forsyth, K, Ono, A et al.. Inhibition of HIV-1 Gag-membrane interactions by specific RNAs. RNA. 2017;23 (3):395-405. doi: 10.1261/rna.058453.116. PubMed PMID:27932583 PubMed Central PMC5311501.
  51. Liu, S, Comandur, R, Jones, CP, Tsang, P, Musier-Forsyth, K. Anticodon-like binding of the HIV-1 tRNA-like element to human lysyl-tRNA synthetase. RNA. 2016;22 (12):1828-1835. doi: 10.1261/rna.058081.116. PubMed PMID:27852925 PubMed Central PMC5113203.
  52. Cantara, WA, Hatterschide, J, Wu, W, Musier-Forsyth, K. RiboCAT: a new capillary electrophoresis data analysis tool for nucleic acid probing. RNA. 2017;23 (2):240-249. doi: 10.1261/rna.058404.116. PubMed PMID:27821510 PubMed Central PMC5238798.
  53. Cantara, WA, Olson, ED, Musier-Forsyth, K. Analysis of RNA structure using small-angle X-ray scattering. Methods. 2017;113 :46-55. doi: 10.1016/j.ymeth.2016.10.008. PubMed PMID:27777026 PubMed Central PMC5253320.
  54. Rye-McCurdy, T, Olson, ED, Liu, S, Binkley, C, Reyes, JP, Thompson, BR et al.. Functional Equivalence of Retroviral MA Domains in Facilitating Psi RNA Binding Specificity by Gag. Viruses. 2016;8 (9):. doi: 10.3390/v8090256. PubMed PMID:27657107 PubMed Central PMC5035970.
  55. Lomidze, L, Kelley, S, Gogichaishvili, S, Metreveli, N, Musier-Forsyth, K, Kankia, B et al.. Sr(2+) induces unusually stable d(GGGTGGGTGGGTGGG) quadruplex dimers. Biopolymers. 2016;105 (11):811-8. doi: 10.1002/bip.22916. PubMed PMID:27416320 .
  56. Kankia, B, Gvarjaladze, D, Rabe, A, Lomidze, L, Metreveli, N, Musier-Forsyth, K et al.. Stable Domain Assembly of a Monomolecular DNA Quadruplex: Implications for DNA-Based Nanoswitches. Biophys J. 2016;110 (10):2169-75. doi: 10.1016/j.bpj.2016.04.031. PubMed PMID:27224482 PubMed Central PMC4880955.
  57. McCauley, MJ, Rouzina, I, Manthei, KA, Gorelick, RJ, Musier-Forsyth, K, Williams, MC et al.. Targeted binding of nucleocapsid protein transforms the folding landscape of HIV-1 TAR RNA. Proc Natl Acad Sci U S A. 2015;112 (44):13555-60. doi: 10.1073/pnas.1510100112. PubMed PMID:26483503 PubMed Central PMC4640786.
  58. Olson, ED, Cantara, WA, Musier-Forsyth, K. New Structure Sheds Light on Selective HIV-1 Genomic RNA Packaging. Viruses. 2015;7 (8):4826-35. doi: 10.3390/v7082846. PubMed PMID:26305251 PubMed Central PMC4576207.
  59. Liu, Z, Vargas-Rodriguez, O, Goto, Y, Novoa, EM, Ribas de Pouplana, L, Suga, H et al.. Homologous trans-editing factors with broad tRNA specificity prevent mistranslation caused by serine/threonine misactivation. Proc Natl Acad Sci U S A. 2015;112 (19):6027-32. doi: 10.1073/pnas.1423664112. PubMed PMID:25918376 PubMed Central PMC4434731.
  60. Novoa, EM, Vargas-Rodriguez, O, Lange, S, Goto, Y, Suga, H, Musier-Forsyth, K et al.. Ancestral AlaX editing enzymes for control of genetic code fidelity are not tRNA-specific. J Biol Chem. 2015;290 (16):10495-503. doi: 10.1074/jbc.M115.640060. PubMed PMID:25724653 PubMed Central PMC4400357.
  61. Rye-McCurdy, T, Rouzina, I, Musier-Forsyth, K. Fluorescence anisotropy-based salt-titration approach to characterize protein-nucleic acid interactions. Methods Mol Biol. 2015;1259 :385-402. doi: 10.1007/978-1-4939-2214-7_23. PubMed PMID:25579598 .
  62. Berkhout, B, Mouland, AJ, Musier-Forsyth, K. Retroviral nucleocapsid protein and assembly. Foreword. Virus Res. 2014;193 :1. doi: 10.1016/j.virusres.2014.10.018. PubMed PMID:25440780 .
  63. Vargas-Rodriguez, O, Musier-Forsyth, K. Structural biology: wobble puts RNA on target. Nature. 2014;510 (7506):480-1. doi: 10.1038/nature13502. PubMed PMID:24919145 .
  64. Wu, H, Wang, W, Naiyer, N, Fichtenbaum, E, Qualley, DF, McCauley, MJ et al.. Single aromatic residue location alters nucleic acid binding and chaperone function of FIV nucleocapsid protein. Virus Res. 2014;193 :39-51. doi: 10.1016/j.virusres.2014.06.002. PubMed PMID:24915282 PubMed Central PMC4252577.
  65. Wang, W, Naiyer, N, Mitra, M, Li, J, Williams, MC, Rouzina, I et al.. Distinct nucleic acid interaction properties of HIV-1 nucleocapsid protein precursor NCp15 explain reduced viral infectivity. Nucleic Acids Res. 2014;42 (11):7145-59. doi: 10.1093/nar/gku335. PubMed PMID:24813443 PubMed Central PMC4066767.
  66. Alemán, EA, de Silva, C, Patrick, EM, Musier-Forsyth, K, Rueda, D. Single-Molecule Fluorescence Using Nucleotide Analogs: A Proof-of-Principle. J Phys Chem Lett. 2014;5 (5):777-781. doi: 10.1021/jz4025832. PubMed PMID:24803990 PubMed Central PMC3985717.
  67. Rye-McCurdy, TD, Nadaraia-Hoke, S, Gudleski-O'Regan, N, Flanagan, JM, Parent, LJ, Musier-Forsyth, K et al.. Mechanistic differences between nucleic acid chaperone activities of the Gag proteins of Rous sarcoma virus and human immunodeficiency virus type 1 are attributed to the MA domain. J Virol. 2014;88 (14):7852-61. doi: 10.1128/JVI.00736-14. PubMed PMID:24789780 PubMed Central PMC4097784.
  68. Qu, J, Kang, SG, Wang, W, Musier-Forsyth, K, Jang, JC. The Arabidopsis thaliana tandem zinc finger 1 (AtTZF1) protein in RNA binding and decay. Plant J. 2014;78 (3):452-67. doi: 10.1111/tpj.12485. PubMed PMID:24635033 PubMed Central PMC4026020.
  69. Jones, CP, Cantara, WA, Olson, ED, Musier-Forsyth, K. Small-angle X-ray scattering-derived structure of the HIV-1 5' UTR reveals 3D tRNA mimicry. Proc Natl Acad Sci U S A. 2014;111 (9):3395-400. doi: 10.1073/pnas.1319658111. PubMed PMID:24550473 PubMed Central PMC3948283.
  70. Bartholow, TG, Sanford, BL, Cao, B, Schmit, HL, Johnson, JM, Meitzner, J et al.. Strictly conserved lysine of prolyl-tRNA Synthetase editing domain facilitates binding and positioning of misacylated tRNA(Pro.). Biochemistry. 2014;53 (6):1059-68. doi: 10.1021/bi401279r. PubMed PMID:24450765 PubMed Central PMC3986007.
  71. Das, M, Vargas-Rodriguez, O, Goto, Y, Suga, H, Musier-Forsyth, K. Distinct tRNA recognition strategies used by a homologous family of editing domains prevent mistranslation. Nucleic Acids Res. 2014;42 (6):3943-53. doi: 10.1093/nar/gkt1332. PubMed PMID:24371276 PubMed Central PMC3973320.
  72. Chaurasiya, KR, McCauley, MJ, Wang, W, Qualley, DF, Wu, T, Kitamura, S et al.. Oligomerization transforms human APOBEC3G from an efficient enzyme to a slowly dissociating nucleic acid-binding protein. Nat Chem. 2014;6 (1):28-33. doi: 10.1038/nchem.1795. PubMed PMID:24345943 PubMed Central PMC3950479.
  73. Mathias, J, Okyere, R, Lomidze, L, Gvarjaladze, D, Musier-Forsyth, K, Kankia, B et al.. Thermal stability of quadruplex primers for highly versatile isothermal DNA amplification. Biophys Chem. 2014;185 :14-8. doi: 10.1016/j.bpc.2013.10.008. PubMed PMID:24317195 .
  74. Wu, H, Mitra, M, Naufer, MN, McCauley, MJ, Gorelick, RJ, Rouzina, I et al.. Differential contribution of basic residues to HIV-1 nucleocapsid protein's nucleic acid chaperone function and retroviral replication. Nucleic Acids Res. 2014;42 (4):2525-37. doi: 10.1093/nar/gkt1227. PubMed PMID:24293648 PubMed Central PMC3936775.
  75. Sun, M, Grigsby, IF, Gorelick, RJ, Mansky, LM, Musier-Forsyth, K. Retrovirus-specific differences in matrix and nucleocapsid protein-nucleic acid interactions: implications for genomic RNA packaging. J Virol. 2014;88 (2):1271-80. doi: 10.1128/JVI.02151-13. PubMed PMID:24227839 PubMed Central PMC3911680.
  76. Mitra, M, Wang, W, Vo, MN, Rouzina, I, Barany, G, Musier-Forsyth, K et al.. The N-terminal zinc finger and flanking basic domains represent the minimal region of the human immunodeficiency virus type-1 nucleocapsid protein for targeting chaperone function. Biochemistry. 2013;52 (46):8226-36. doi: 10.1021/bi401250a. PubMed PMID:24144434 PubMed Central PMC3875364.
  77. Webb, JA, Jones, CP, Parent, LJ, Rouzina, I, Musier-Forsyth, K. Distinct binding interactions of HIV-1 Gag to Psi and non-Psi RNAs: implications for viral genomic RNA packaging. RNA. 2013;19 (8):1078-88. doi: 10.1261/rna.038869.113. PubMed PMID:23798665 PubMed Central PMC3708528.
  78. Johnson, JM, Sanford, BL, Strom, AM, Tadayon, SN, Lehman, BP, Zirbes, AM et al.. Multiple pathways promote dynamical coupling between catalytic domains in Escherichia coli prolyl-tRNA synthetase. Biochemistry. 2013;52 (25):4399-412. doi: 10.1021/bi400079h. PubMed PMID:23731272 PubMed Central PMC3749879.
  79. Vargas-Rodriguez, O, Musier-Forsyth, K. Exclusive use of trans-editing domains prevents proline mistranslation. J Biol Chem. 2013;288 (20):14391-14399. doi: 10.1074/jbc.M113.467795. PubMed PMID:23564458 PubMed Central PMC3656294.
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