Dr. Venkat Gopalan
Department of Chemistry and Biochemistry
Center for RNA Biology
The Ohio State University
484 West 12th Avenue
774 Biological Sciences Building
Columbus, OH 43210
Fax: (614) 292-6773
Email: gopalan.5@osu.edu
Education and Training |
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| 1995 | Visiting Scientist MRC Laboratory of Molecular Biology, Cambridge, UK Mentor: Sir Aaron Klug |
| 1992 – 1997 | Postdoctoral Research Associate Yale University, New Haven, CT Mentor: Dr. Sidney Altman |
| 1991 | Ph.D. in Biochemistry University of New Mexico, Albuquerque, NM Advisor: Dr. Robert H. Glew |
| 1986 | B.S. in Chemistry University of Madras, Madras, India |
Professional Positions |
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| 2010 to date | Professor Department of Chemistry and Biochemistry (renamed after a merger in July 2012) The Ohio State University, Columbus, OH |
| 2003 – 2010 | Associate Professor Department of Biochemistry The Ohio State University, Columbus, OH |
| 1998 – 2003 | Assistant Professor Department of Biochemistry The Ohio State University, Columbus, OH |
| 1995 | Visiting Scientist MRC Laboratory of Molecular Biology, Cambridge, UK Mentor: Sir Aaron Klug, Professor and Director |
| 1992 – 1997 | Postdoctoral Research Associate Department of Biology Yale University, New Haven, CT Mentor: Sidney Altman, Sterling Professor of Biology and Chemistry |
| 1990 – 1991 | Graduate Student Researcher Department of Biochemistry University of New Mexico, Albuquerque, NM Advisor: Robert H. Glew, Professor and Chairperson |
| 1986 – 1990 | Graduate Student Researcher Department of Microbiology, Biochemistry, and Molecular Biology University of Pittsburgh School of Medicine, Pittsburgh, PA Advisor: Robert H. Glew, Professor |
Honors and Awards |
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| 2020 | OSU College of Arts and Sciences Student Council Outstanding Teaching Award |
| 2018 | OSU College of Arts and Sciences Diversity Enhancement Faculty Award (with Drs. Susan Cole, Department of Molecular Genetics; Jane Jackman, Department of Chemistry and Biochemistry; and Amanda Simcox, Department of Molecular Genetics) |
| 2017 – 2022 | Melvin S. Newman Professor of Chemistry and Biochemistry |
| 2010 | The Ohio State University Alumni Distinguished Teaching Award |
| 2010 | Bringing the World into the Classroom: American Council of Education Award to Recognize Innovative Use of Technology to Promote Internationalization (Finalist) |
| 2009 | The Ohio State University Rosalene Sedgwick Faculty Service Award |
| 2008 | The Ohio State University Harlan Hatcher Award for Academic Excellence |
| 2007 | The Ohio State University Department of Biochemistry Award for Excellence |
| 2005 | The Ohio State University College of Biological Sciences Dean’s Award for Classroom Teaching |
| 2004 | The Ohio State University Colleges of Arts and Sciences Student Council Outstanding Teacher Award (Finalist) |
| 2003 | The Ohio State University College of Biological Sciences Dean’s Award for Undergraduate Research Mentoring |
| 2003 – 2008 | National Science Foundation CAREER Award |
| 1995 – 1996 | Anna Fuller Cancer Research Fund Postdoctoral Fellowship |
| 1993 – 1995 | Donaghue Medical Research Foundation Postdoctoral Fellowship |
Publications (prior to independent position at OSU) |
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| *Corresponding author(s) | |
| Gopalan V, Golbik R, Schreiber G, Fersht AR, and Altman S*. (1997) Fluorescence properties of a tryptophan residue in an aromatic core of the protein subunit of ribonuclease P from Escherichia coli. J. Mol. Biol., 267: 765-769. | |
| Gopalan V, Baxevanis AD, Landsman D, and Altman S*. (1997) Analysis of the functional role of conserved residues in the protein subunit of ribonuclease P from Escherichia coli. J. Mol. Biol., 267: 818-829. | |
| Gopalan V, Talbot SJ, and Altman S*. (1994) RNA-protein interactions in RNase P. In K. Nagai and I. Mattaj (Eds.), RNA-Protein Interactions – Frontiers in Molecular Biology (pp. 103-126). Oxford, UK: Oxford University Press. | |
| Glew RH*, Gopalan V, Forsyth GW, and Vander Jagt DJ. (1993) The mammalian cytosolic broad-specificity ß-glucosidase. In A. Esen (Ed.), ß-glucosidases: Biochemistry and Molecular Biology (pp. 83-112). Washington, D.C.: American Chemical Society. | |
| Gopalan V, Pastuszyn A, Galey WR Jr, and Glew RH*. (1992) Exolytic hydrolysis of toxic plant glucosides by guinea pig liver cytosolic ß-glucosidase. J. Biol. Chem., 267: 14027-14032. | |
| Gopalan V, Vander Jagt DJ, Libell DP, and Glew RH*. (1992) Transglucosylation as a probe of the mechanism of action of mammalian cytosolic ß-glucosidase. J. Biol. Chem., 267: 9629-9638. | |
| Lai LB, Gopalan V, and Glew RH*. (1992) Continuous spectrophotometric assays for ß-glucosidases acting on the plant glucosides L-picein and prunasin. Anal. Biochem., 200: 365-369. | |
| Glew, RH*, Gopalan V, Hubbell CA, Devraj RV, Lawson RA, Diven WF, and Mannock DA. (1991) 2,3-Di-O-tetradecyl-1-O-(ß-D-glucopyranosyl)-sn-glycerol is a substrate for human glucocerebrosidase. Biochem. J., 274: 557-563. | |
| Glew RH*, Gopalan V, Hubbell CA, Beutler E, Geil JD, and Lee RE. (1991) A case of nonneurologic Gaucher’s disease that biochemically resembles the neurologic types. J. Neuropathol. Exp. Neurol., 50: 108-117. | |
| Butcher BA, Gopalan V, Lee RE, Richards TC, Waggoner AS, and Glew RH*. (1989) Use of 4-heptylumbelliferyl-ß-D-glucoside to identify Gaucher’s disease heterozygotes. Clin. Chim. Acta, 184: 235-242. | |
| Gopalan V, Glew RH*, Libell DP, and DePetro JJ. (1989) The dual effects of alcohols on the kinetic properties of guinea pig liver cytosolic ß-glucosidase. J. Biol. Chem., 264: 15418-15422. | |
| Gopalan V, Daniels LB, Glew RH*, and Claeyssens M. (1989) Kinetic analysis of the interaction of alkyl glycosides with two human ß-glucosidases. Biochem. J., 262: 541-548. | |