For the press release, please click here.
For the Waters’ Centers of Innovation program, please click here.
Congratulations to Sophie!
She is the winner of the Royal Society of Chemistry Ronald Belcher Award 2015.
Awarded for her outstanding innovation in native mass spectrometry of conformationally dynamic proteins
Click here to access Vicki’s video “Measure Protein Shape and Topology using Mass Spectrometry” on SelectScience
American Society for Mass Spectrometry in St. Louis, May 31-June 4, 2015
Oral presentations from the Wysocki group
MOC am 09:30 Surface Induced Dissociation Reveals Substructural Information Consistent With The Interfacial Analysis Of Protein Complexes; Sophie R. Harvey; Royston S. Quintyn; Yang Song; Jing Yan; Aniruddha N. Sahasrabuddhe; Vicki H. Wysocki; The Ohio State University, Columbus, Ohio
TOF am 09:10 Phosphoproteomic and Proteomic Identification of Oncogenic Pathways in LKB1 Dependent NonSmall Cell Lung Cancer by Two-Dimensional LCMS/MS; Nilini Ranbaduge; Joseph Amann; Tadaaki Yamada; Zhen Wang; David Carbone; Vicki Wysocki; The Ohio State University, Columbus, OH
WOF am 09:50 Structure Elucidation of Toyocamycin Nitrile Hydratase, a Hetero-hexameric Protein Complex, by Mass Spectrometry; Yang Song1 ; Micah Nelp2 ; Vahe Bandarian2 ; Vicki H. Wysocki1 ; 1 The Ohio State University, Columbus, OH; 2 The University of Arizona, Tucson, AZ
Poster presentations from the Wysocki group
MP 550 Selective Proteomics Analysis Using Congo Red as a Precipitating Reagent; Hongwu Jing1 ; Irina A. Buhimschi2,3; Guomao Zhao2 ; Michelle Axe4 ; Catalin S. Buhimschi3 ; Vicki Wysocki1 ; 1 Dept. Chem. Biochem., The Ohio State University, Columbus, OH; 2 Research Inst. at Nationwide Children’s Hospital, Columbus, OH; 3 Dept. OB/ GYN, The Ohio State University, Columbus, OH; 4 Dept. Biochem. Mol. Biol., Otterbein University, Westerville, OH
TP 073 Surface Induced Dissociation Utilized to Characterize Protein Complexes Trapped in the Trap Cell of a Q-TOF Instrument; Jing Yan1 ; Sophie R. Harvey1 ; Jeff Brown2 ; Emmy Hoyes2 ; Vicki H. Wysocki1 ; 1 The Ohio State University, Columbus, OH; 2 Waters Corporation, Wilmslow, UK
TP 476 Surface-Induced Dissociation/Ion Mobility of Pyruvate Kinase: Interface Area and Subunit Packing; Aniruddha Sahasrabuddhe; Vicki Wysocki; The Ohio State University, Columbus, Ohio
WP 173 Native Mass Spectrometry of the ProRS/tRNAPro/YbaK Ternary Complex Supports the Triple-Sieve Mechanism of Editing; Akiko Tanimoto; Lin Chen; Marina Bakhtin; Vicki Wysocki; Karin Musier-Forsyth; The Ohio State University, Columbus, OH
WP 588 Multisubunit Protein Interactions and ProteinLigand Binding Sites Revealed By Surface Induced Dissociation Ion Mobility-Mass Spectrometry; Yue Ju; Royston Quintyn; Vicki Wysocki; The Ohio State University, Columbus, Ohio
American Society for Mass Spectrometry in Baltimore June 16-19
Oral presentations from the Wysocki group
TOD am 09:10 Surface Induced Dissociation (SID) and Collision Induced Dissociation (CID) Characterization of Human Nucleosomes; Yun Zhang*, Xin Ma, Morgan Bernier, Cecil Howard, Michael Poirier, Jennifer Ottesen, Vicki Wysocki
WOD pm 03:50 Effect of conformational flexibility on gas-phase unfolding of noncovalent protein homodimers probed by CID and SID; Yang Song*, Yun Zhang, Royston Quintyn, Mowei Zhou, Vicki Wysocki
ThOF am 09:30 Mass-spectrometry-based footprinting to map the precursor tRNA binding sites in a protein-only RNase P variant; Tien-Hao Chen, Akiko Tanimoto*, Xin Ma, Wei Zhou, Jikang Wu, Venkat Gopalan, Vicki Wysocki
ThOC pm 2:50 Using Surface Induced Dissociation-Ion Mobility (SID-IM) to distinguish the different interfaces that exist in tetrameric protein complexes; Royston Quintyn*, Jing Yan, Vicki Wysocki
ThOA pm 3:10 Ion mobility studies of isomeric species lycopene, alpha-carotene, and beta-carotene and the retention of trans and cis conformation; Matthew Bernier*, Rachel Kopec, Steven Schwartz, Vicki Wysocki
Poster presentations from the Wysocki group
MP 138 Multiple dissociation pathways of ganglioside-toxin complexes revealed by collision induced dissociation and surface induced dissociation in the gas phase; Yue Ju*, Yun Zhang, Vicki Wysocki
TP 227 Discovery and Validation of Invasive Aspergillosis Protein Biomarkers in Human Bronchoalveolar Lavage Fluid; Chengsi Huang*, Jason W. McCarthy, Karen Wood, Luke Herren, Marta Feldmesser, Vicki H. Wysocki
ThP 113 Covalent Fragments from SID Fragmentation of the Helical Protein ROP Correlate with Precursor Secondary Structure; Lindsay Morrison*, Thomas Magliery, Vicki Wysocki
ThP 259 Evaluation of protein levels in serum after combinatorial peptide ligand library (CPLL) treatment; Jin Ren*, Ran An, Chengsi Huang, Yun Zhang, Vicki Wysocki
ThP 296 Two-Dimensional Liquid Chromatography Coupled to Mass Spectrometry for Proteomic Profiling of Paraffin Embedded Lung Tumor Tissues; Nilini Ranbaduge*, Ferdinando Cerciello, Joseph Amann, David Carbone, Vicki Wysocki
American Society for Mass Spectrometry in Minneapolis June 9-13
Oral presentations from the Wysocki group
MOG am 08:30 Evidence of Third Residue Involvement in Diketopiperazine and Oxazolone b2 Ion Formation in NAXIG and QAXIG Pentapeptides; Lindsay Morrison, Julia Chamot-Rooke, Vicki Wysocki
MOF pm 2:30 Dissecting Large Non-covalent Ring Protein Complexes by Surface Induced Dissociation Combined with Ion Mobility; Mowei Zhou, Yun Zhang, Vicki Wysocki
Poster presentations from the Wysocki group
TP 012 Comparison between Surface-Induced Dissociation (SID) and Collision-Induced Dissociation (CID) of Ion- Mobility (IM)-Separated Detergent Clusters; Yun Zhang, Mowei Zhou, Xin Ma, Vicki H. Wysocki
TP 123 Modification of the Prolyl Ring of Val-Pro-Ala and the Impact of this Modification on b2 ion Structure; Matthew Bernier, Ashley Gucinski, Julia Chamot-Rooke, Vicki Wysocki
TP 222 Top-down Assisted Bottom-up Method for Avian Hemoglobin Sequencing; Yang Song, Ünige A. Laskay, Alan G. Barbour, Vicki H. Wysocki
TP 288 Finding Invasive Aspergillosis Protein Biomarkers in Patient Bronchoalveolar Lavage Fluid; Chengsi Huang, Jason W. McCarthy, Yun Zhang, Carmen Luraschi- Monjagatta, Donna Wolk, KS Knox, Marta Feldmesser, Vicki H. Wysocki
TP 291 Valley Fever: MS Based Diagnostics and Potential Vaccine Characterization; Andrew VanSchoiack, Tao Peng, Lourdes Lewis, John Galgiani, Vicki Wysocki
WP 413 Improved Structural Characterization of Stable Non- Covalent Protein Complexes by Surface Induced Dissociation (SID); Xin Ma, Mowei Zhou, Vicki H. Wysocki
Matthew Bernier, Yue (Linny) Ju, Lindsay Morrison joined the Turkey Run Conference 2012 in Indiana.
Chengsi (Michelle) Huang and Mowei Zhou gave oral presentations at the International Mass Spectrometry Conference 2012 at Kyoto, Japan.
Dr. Vicki Wysocki joined OSU in August 2012 as an Ohio Eminent Scholar. The whole group moved from University of Arizona, Tucson to Ohio State University, Columbus.